Deciphering the metabolic fates of a green fluorescent protein (GFP)-like fluorophore: Metabolite identification, isoenzyme contribution and species differences

[1]  Maxim M. Perfilov,et al.  Design of red-shifted and environment-sensitive fluorogens based on GFP chromophore core , 2020 .

[2]  Xinrui Duan,et al.  A genetically encoded fluorescent biosensor for detecting nitroreductase activity in living cancer cells. , 2019, Analytica chimica acta.

[3]  J. Pedelacq,et al.  Development and Applications of Superfolder and Split Fluorescent Protein Detection Systems in Biology , 2019, International journal of molecular sciences.

[4]  C. Lau,et al.  A conformational switch-based fluorescent biosensor for homogeneous detection of telomerase activity. , 2019, Talanta.

[5]  U. Argikar,et al.  UDP-Glucuronosyltransferases , 2019, Handbook of Drug Metabolism.

[6]  Ruijie Deng,et al.  Cascade Transcription Amplification of RNA Aptamer for Ultrasensitive MicroRNA Detection. , 2019, Analytical chemistry.

[7]  J. Hainfeld,et al.  Small, Long Blood Half-Life Iodine Nanoparticle for Vascular and Tumor Imaging , 2018, Scientific Reports.

[8]  M. Finel,et al.  Identification and characterization of human UDP-glucuronosyltransferases responsible for xanthotoxol glucuronidation , 2018, Xenobiotica; the fate of foreign compounds in biological systems.

[9]  R. Tukey,et al.  Species differences in drug glucuronidation: Humanized UDP-glucuronosyltransferase 1 mice and their application for predicting drug glucuronidation and drug-induced toxicity in humans. , 2017, Drug metabolism and pharmacokinetics.

[10]  Simon P. Mackay,et al.  Synthetic biological approaches for RNA labelling and imaging: design principles and future opportunities. , 2017, Current opinion in biotechnology.

[11]  Guangbo Ge,et al.  A Practical and High-Affinity Fluorescent Probe for Uridine Diphosphate Glucuronosyltransferase 1A1: A Good Surrogate for Bilirubin. , 2017, Journal of medicinal chemistry.

[12]  Zhuo Chen,et al.  Synthesis of a cationic poly(p-phenylenevinylene) derivative for lysosome-specific and long-term imaging , 2017 .

[13]  Minyong Li,et al.  cybLuc: An Effective Aminoluciferin Derivative for Deep Bioluminescence Imaging , 2017, Analytical chemistry.

[14]  Dmitry M Kolpashchikov,et al.  Split Spinach Aptamer for Highly Selective Recognition of DNA and RNA at Ambient Temperatures , 2016, Chembiochem : a European journal of chemical biology.

[15]  Taekjip Ha,et al.  Tandem Spinach Array for mRNA Imaging in Living Bacterial Cells , 2015, Scientific Reports.

[16]  M. Finel,et al.  An optimized ratiometric fluorescent probe for sensing human UDP-glucuronosyltransferase 1A1 and its biological applications. , 2015, Biosensors & bioelectronics.

[17]  Z. Xiu,et al.  Glucuronidation of bavachinin by human tissues and expressed UGT enzymes: Identification of UGT1A1 and UGT1A8 as the major contributing enzymes. , 2015, Drug metabolism and pharmacokinetics.

[18]  W. Xu,et al.  Identification and characterization of human UDP‐glucuronosyltransferases responsible for the in‐vitro glucuronidation of arctigenin , 2015, The Journal of pharmacy and pharmacology.

[19]  C. A. Kellenberger,et al.  Live Cell Imaging Using Riboswitch-Spinach tRNA Fusions as Metabolite-Sensing Fluorescent Biosensors. , 2015, Methods in molecular biology.

[20]  Grigory S. Filonov,et al.  Broccoli: Rapid Selection of an RNA Mimic of Green Fluorescent Protein by Fluorescence-Based Selection and Directed Evolution , 2014, Journal of the American Chemical Society.

[21]  J. Piccirilli,et al.  A G-Quadruplex-Containing RNA Activates Fluorescence in a GFP-Like Fluorophore , 2014, Nature chemical biology.

[22]  M. Nagata,et al.  Optimized Methods for Targeted Peptide-Based Quantification of Human Uridine 5′-Diphosphate-Glucuronosyltransferases in Biological Specimens Using Liquid Chromatography–Tandem Mass Spectrometry , 2014, Drug Metabolism and Disposition.

[23]  L. Berry,et al.  Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor , 2014, Drug Metabolism and Disposition.

[24]  Guangbo Ge,et al.  Selectivity for inhibition of nilotinib on the catalytic activity of human UDP-glucuronosyltransferases , 2014, Xenobiotica; the fate of foreign compounds in biological systems.

[25]  Sheng-Li Yang,et al.  Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin. , 2014, Drug metabolism and pharmacokinetics.

[26]  Taekjip Ha,et al.  Understanding the photophysics of the spinach-DFHBI RNA aptamer-fluorogen complex to improve live-cell RNA imaging. , 2013, Journal of the American Chemical Society.

[27]  Hendrik Neubert,et al.  Targeted quantitative proteomics for the analysis of 14 UGT1As and -2Bs in human liver using NanoUPLC-MS/MS with selected reaction monitoring. , 2013, Journal of proteome research.

[28]  Guangbo Ge,et al.  Potent and selective inhibition of magnolol on catalytic activities of UGT1A7 and 1A9 , 2012, Xenobiotica; the fate of foreign compounds in biological systems.

[29]  S. Jaffrey,et al.  RNA Mimics of Green Fluorescent Protein , 2011, Science.

[30]  Guangbo Ge,et al.  Determination of propofol UDP-glucuronosyltransferase (UGT) activities in hepatic microsomes from different species by UFLC-ESI-MS. , 2011, Journal of pharmaceutical and biomedical analysis.

[31]  K. Bock.  Functions and transcriptional regulation of adult human hepatic UDP-glucuronosyl-transferases (UGTs): mechanisms responsible for interindividual variation of UGT levels. , 2010, Biochemical pharmacology.

[32]  Yan-Yan Zhang,et al.  Identification and Characterization of Human UDP-Glucuronosyltransferases Responsible for the In Vitro Glucuronidation of Daphnetin , 2010, Drug Metabolism and Disposition.

[33]  Yuko Ito,et al.  Human CYPs involved in drug metabolism: structures, substrates and binding affinities , 2010, Expert opinion on drug metabolism & toxicology.

[34]  James H. Adair,et al.  Near-infrared emitting fluorophore-doped calcium phosphate nanoparticles for in vivo imaging of human breast cancer. , 2008, ACS nano.

[35]  A. Waggoner,et al.  Synthesis of new fluorogenic cyanine dyes and incorporation into RNA fluoromodules. , 2008, Organic letters.

[36]  Robert E Campbell,et al.  Structural basis for reversible photobleaching of a green fluorescent protein homologue , 2007, Proceedings of the National Academy of Sciences.

[37]  J. Miners,et al.  Quantitative prediction of in vivo inhibitory interactions involving glucuronidated drugs from in vitro data: the effect of fluconazole on zidovudine glucuronidation. , 2006, British journal of clinical pharmacology.

[38]  K. Solntsev,et al.  Probing the decay coordinate of the green fluorescent protein: arrest of cis-trans isomerization by the protein significantly narrows the fluorescence spectra. , 2006, Journal of the American Chemical Society.

[39]  D. Ehrhardt,et al.  GFP technology for live cell imaging. , 2003, Current opinion in plant biology.

[40]  George H. Patterson,et al.  A Photoactivatable GFP for Selective Photolabeling of Proteins and Cells , 2002, Science.

[41]  M. Zimmer,et al.  Green fluorescent protein (GFP): applications, structure, and related photophysical behavior. , 2002, Chemical reviews.

[42]  J. Magdalou,et al.  Characterization of catechol glucuronidation in rat liver. , 2002, Drug metabolism and disposition: the biological fate of chemicals.

[43]  Stephen R. Meech,et al.  Radiationless relaxation in a synthetic analogue of the green fluorescent protein chromophore , 2001 .

[44]  W. Ward,et al.  Reversible denaturation of Aequorea green-fluorescent protein: physical separation and characterization of the renatured protein. , 1982, Biochemistry.