Real-time, programmable, digital signal-processing electronics for extracting the information from a detector module for multi-modality PET/SPECT/CT scanners

Measurements performed by manufacturers on their PET devices reveal a limitation of the electronics in extracting the properties of particles hitting the detector. As a consequence, either a lead collimator with holes is placed in front of the detector (2-D mode) preventing many photons which are not sufficiently aligned with the holes from ever reaching the detector, or many photons are lost because the electronics cannot fully process the data and separate the good event from the bad events. In order to overcome the above limitation, a data acquisition system based on the programmable 3D-Flow processor has been designed for acquiring data from modules for multi-modality PET/SPECT/CT. The modular electronics allows for digital data to be acquired from all sensors included in a given view angle of the detector. Each channel can sustain an input data rate of 20 MHz, 64-bit word; 40 MHz, 32-bit word; or 80 MHz, 16-bit word. The bits at each electronic channel correspond to spatial, timing, and energy information from photomultipliers, avalanche photodiodes (APD), photodiodes, or other sensors. The programmable circuit performs digital signal-processing operations on the incoming bit string such as: (a) variable digital integration time (or pileup identification/correction) which allows for the maximum count rate capabilities while preserving spatial resolution; (b) depth of interaction which reduces the parallax error based on pulse shape discrimination (PSD), and/or pulse height discrimination (PHD); (c) improvement of the signal-to-noise ratio; (d) centroid calculation to improve spatial resolution or/and techniques of most likely position given the statistical nature of the signals; (e) correlation with neighboring signals; and (f) improving the timing resolution from the information received from the time-to-digital converter and pulse shape analysis.

[1]  Joel S. Karp,et al.  Evemt Localization in a Continuous Scintillation Detector Using Digital Processing , 1986, IEEE Transactions on Nuclear Science.

[2]  R. Nutt,et al.  Performance of a PET detector module utilizing an array of silicon photodiodes to identify the crystal of interaction , 1992 .

[3]  R. Nutt,et al.  Testing 144- and 256-crystal BGO block detectors , 1993, 1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference.

[5]  Simon R. Cherry,et al.  A comparison of PET detector modules employing rectangular and round photomultiplier tubes , 1995 .

[6]  E. Beuville,et al.  A "Winner-Take-All" IC for determining the crystal of interaction in PET detectors , 1996 .

[7]  T. Lewellen,et al.  Design of a depth of interaction (DOI) PET detector module , 1997, 1997 IEEE Nuclear Science Symposium Conference Record.

[8]  W. Moses,et al.  Characterization of a 64 channel PET detector using photodiodes for crystal identification , 1997 .

[9]  M. Ter-pogossian,et al.  A GSO(Ce) block type detector for high count rate PET applications , 1994, Proceedings of 1994 IEEE Nuclear Science Symposium - NSS'94.

[10]  Haiming Yu,et al.  A high-speed and high-precision Winner-Select-Output (WSO) ASIC , 1997 .

[11]  G Muehllehner,et al.  Three-dimensional imaging characteristics of the HEAD PENN-PET scanner. , 1997, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[12]  Edward J. Hoffman,et al.  Use of digital front end electronics for optimization of a modular PET detector , 1991, Conference Record of the 1991 IEEE Nuclear Science Symposium and Medical Imaging Conference.

[13]  D. B. Crosetto A modular VME or IBM PC based data acquisition system for multi-modality PET/CT scanners of different sizes and detector types , 2000, 2000 IEEE Nuclear Science Symposium. Conference Record (Cat. No.00CH37149).

[14]  Michael J. Paulus,et al.  A Custom CMOS Integrated Circuit For PET Tomograph Front-end Applications , 1993, 1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference.

[15]  R. Lecomte,et al.  A novel APD-based detector module for multi-modality PET/SPECT/CT scanners , 1998, 1998 IEEE Nuclear Science Symposium Conference Record. 1998 IEEE Nuclear Science Symposium and Medical Imaging Conference (Cat. No.98CH36255).