Improved Discrimination of Tumors with Low and Heterogeneous EGFR Expression in Fluorescence-Guided Surgery Through Paired-Agent Protocols

[1]  Antonio R. Montaño,et al.  TRIPODD: a Novel Fluorescence Imaging Platform for In Situ Quantification of Drug Distribution and Therapeutic Response , 2021, Molecular Imaging and Biology.

[2]  K. Tichauer,et al.  Noninvasive quantification of target availability during therapy using paired-agent fluorescence tomography , 2020, Theranostics.

[3]  B. Pogue,et al.  Dual‐agent fluorescent labeling of soft‐tissue sarcomas improves the contrast based upon targeting both interstitial and cellular components of the tumor milieu , 2020, Journal of surgical oncology.

[4]  K. Schepman,et al.  Fluorescence-guided imaging for resection margin evaluation in head and neck cancer patients using cetuximab-800CW: A quantitative dose-escalation study , 2020, Theranostics.

[5]  Greg M. Thurber,et al.  Practical Guide for Quantification of In Vivo Degradation Rates for Therapeutic Proteins with Single-Cell Resolution Using Fluorescence Ratio Imaging , 2020, Pharmaceutics.

[6]  N. S. van den Berg,et al.  Optimal Dosing Strategy for Fluorescence-Guided Surgery with Panitumumab-IRDye800CW in Head and Neck Cancer , 2019, Molecular Imaging and Biology.

[7]  Zhen Cheng,et al.  First-in-human liver-tumour surgery guided by multispectral fluorescence imaging in the visible and near-infrared-I/II windows , 2019, Nature Biomedical Engineering.

[8]  Brian W Pogue,et al.  Preclinical imaging of epidermal growth factor receptor with ABY‐029 in soft‐tissue sarcoma for fluorescence‐guided surgery and tumor detection , 2019, Journal of surgical oncology.

[9]  B. Martin,et al.  The Sentinel Margin: Intraoperative Ex Vivo Specimen Mapping Using Relative Fluorescence Intensity , 2019, Clinical Cancer Research.

[10]  John Y. K. Lee,et al.  Intraoperative Imaging with Second Window Indocyanine Green for Head and Neck Lesions and Regional Metastasis , 2019, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[11]  Gooitzen M van Dam,et al.  Roadmap for the Development and Clinical Translation of Optical Tracers Cetuximab-800CW and Trastuzumab-800CW , 2019, The Journal of Nuclear Medicine.

[12]  Guolan Lu,et al.  Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence. , 2018, Cancer research.

[13]  N. S. van den Berg,et al.  Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers , 2018, Theranostics.

[14]  R. Tsien,et al.  Sensitive in vivo Visualization of Breast Cancer Using Ratiometric Protease-activatable Fluorescent Imaging Agent, AVB-620 , 2017, Theranostics.

[15]  Sunil Singhal,et al.  The second window ICG technique demonstrates a broad plateau period for near infrared fluorescence tumor contrast in glioblastoma , 2017, PloS one.

[16]  E. Rosenthal,et al.  Sensitivity and Specificity of Cetuximab-IRDye800CW to Identify Regional Metastatic Disease in Head and Neck Cancer , 2017, Clinical Cancer Research.

[17]  E. Rosenthal,et al.  Effects of an Unlabeled Loading Dose on Tumor-Specific Uptake of a Fluorescently Labeled Antibody for Optical Surgical Navigation , 2017, Molecular Imaging and Biology.

[18]  Keith Paulsen,et al.  Toxicity and Pharmacokinetic Profile for Single-Dose Injection of ABY-029: a Fluorescent Anti-EGFR Synthetic Affibody Molecule for Human Use , 2017, Molecular Imaging and Biology.

[19]  Linton T. Evans,et al.  Simultaneous In Vivo Fluorescent Markers for Perfusion, Protoporphyrin Metabolism, and EGFR Expression for Optically Guided Identification of Orthotopic Glioma , 2016, Clinical Cancer Research.

[20]  Brian W Pogue,et al.  Review of fluorescence guided surgery systems: identification of key performance capabilities beyond indocyanine green imaging , 2016, Journal of biomedical optics.

[21]  Brian W. Pogue,et al.  Fluorescent Affibody Molecule Administered In Vivo at a Microdose Level Labels EGFR Expressing Glioma Tumor Regions , 2016, Molecular Imaging and Biology.

[22]  Hiroshi Maeda,et al.  Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity. , 2015, Advanced drug delivery reviews.

[23]  Jonathan T. C. Liu,et al.  Quantitative in vivo cell-surface receptor imaging in oncology: kinetic modeling and paired-agent principles from nuclear medicine and optical imaging , 2015, Physics in medicine and biology.

[24]  Joshua S Richman,et al.  Safety and Tumor Specificity of Cetuximab-IRDye800 for Surgical Navigation in Head and Neck Cancer , 2015, Clinical Cancer Research.

[25]  Tayyaba Hasan,et al.  Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach. , 2014, Cancer research.

[26]  Tayyaba Hasan,et al.  Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging , 2014, Nature Medicine.

[27]  T. Hasan,et al.  Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors , 2012, Physics in medicine and biology.

[28]  Tayyaba Hasan,et al.  Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging. , 2012, Journal of biomedical optics.

[29]  Nihal Ahmad,et al.  Dose translation from animal to human studies revisited , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[30]  R. Nason,et al.  The clinical significance of the positive surgical margin in oral cancer. , 2007, Oral oncology.

[31]  A. Ruifrok,et al.  Quantification of histochemical staining by color deconvolution. , 2001, Analytical and quantitative cytology and histology.

[32]  R. Day,et al.  Levels of TGF-α and EGFR Protein in Head and Neck Squamous Cell Carcinoma and Patient Survival , 1998 .

[33]  F Demard,et al.  Characterization, quantification, and potential clinical value of the epidermal growth factor receptor in head and neck squamous cell carcinomas , 1991, Head & neck.