Development of a mouse model mimicking key aspects of a viral asthma exacerbation.
暂无分享,去创建一个
D. Clarke | M. Sleeman | N. H. Davis | J. Majithiya | D. Corkill | Siân Piper | R. May | Arthur Lewis
[1] S. Johnston,et al. γδT cells suppress inflammation and disease during rhinovirus-induced asthma exacerbations , 2013, Mucosal Immunology.
[2] S. Johnston,et al. The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity , 2013, Nature Medicine.
[3] T. Lewis,et al. Macrophage/epithelial cell CCL2 contributes to rhinovirus-induced hyperresponsiveness and inflammation in a mouse model of allergic airways disease. , 2013, American journal of physiology. Lung cellular and molecular physiology.
[4] P. O'Byrne,et al. Safety and efficacy of a CXCR2 antagonist in patients with severe asthma and sputum neutrophils: a randomized, placebo‐controlled clinical trial , 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[5] Y. Nakanishi,et al. IL-6 Induced By Double-Stranded RNA Augments Allergic Inflammation Via Suppression Of Foxp3+T Cell/IL-10 Axis , 2012, ATS 2012.
[6] J. Alcorn,et al. Airway Hyperresponsiveness and Inflammation: Causation, Correlation, or No Relation? , 2012, Journal of allergy & therapy.
[7] Lee, Jk,et al. Lebrikizumab treatment in adults with asthma. , 2011 .
[8] S. Johnston,et al. Asthma exacerbations: Origin, effect, and prevention , 2011, Journal of Allergy and Clinical Immunology.
[9] David J. Miller,et al. MDA5 and TLR3 Initiate Pro-Inflammatory Signaling Pathways Leading to Rhinovirus-Induced Airways Inflammation and Hyperresponsiveness , 2011, PLoS pathogens.
[10] 高山 聡. Synthetic double-stranded RNA enhances airway inflammation and remodelling in a rat model of asthma , 2011 .
[11] Carla M. T. Bauer,et al. Treating Viral Exacerbations of Chronic Obstructive Pulmonary Disease: Insights from a Mouse Model of Cigarette Smoke and H1N1 Influenza Infection , 2010, PloS one.
[12] Ying Zhao,et al. Rhinovirus Infection of Allergen-Sensitized and -Challenged Mice Induces Eotaxin Release from Functionally Polarized Macrophages , 2010, The Journal of Immunology.
[13] W. Busse. The relationship of airway hyperresponsiveness and airway inflammation: Airway hyperresponsiveness in asthma: its measurement and clinical significance. , 2010, Chest.
[14] Christopher P. Thomas,et al. Inhaled house dust mite induces pulmonary T helper 2 cytokine production , 2009, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
[15] Barmak Modrek,et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. , 2009, American journal of respiratory and critical care medicine.
[16] H. Magnussen,et al. SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects , 2009, European Respiratory Journal.
[17] S. Johnston,et al. Rhinovirus-induced lower respiratory illness is increased in asthma and related to virus load and Th1/2 cytokine and IL-10 production , 2008, Proceedings of the National Academy of Sciences.
[18] K. Ulrich,et al. Anti-inflammatory modulation of chronic airway inflammation in the murine house dust mite model. , 2008, Pulmonary pharmacology & therapeutics.
[19] C. D. Dela Cruz,et al. Cigarette smoke selectively enhances viral PAMP- and virus-induced pulmonary innate immune and remodeling responses in mice. , 2008, The Journal of clinical investigation.
[20] I. Adcock,et al. Molecular mechanisms of corticosteroid resistance. , 2008, Chest.
[21] J. Bates,et al. The synergistic interactions of allergic lung inflammation and intratracheal cationic protein. , 2008, American journal of respiratory and critical care medicine.
[22] R. A. Killington,et al. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation , 2008, Nature Medicine.
[23] Y. Gho,et al. TH2 and TH1 lung inflammation induced by airway allergen sensitization with low and high doses of double-stranded RNA. , 2007, The Journal of allergy and clinical immunology.
[24] J. Bates,et al. Intrinsic and antigen-induced airway hyperresponsiveness are the result of diverse physiological mechanisms. , 2007, Journal of applied physiology.
[25] D. Strachan,et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys , 2006, The Lancet.
[26] S. Peters,et al. Uncontrolled asthma: a review of the prevalence, disease burden and options for treatment. , 2006, Respiratory medicine.
[27] P. Gibson,et al. Interleukin-10 gene expression in acute virus-induced asthma. , 2005, American journal of respiratory and critical care medicine.
[28] M. Schaller,et al. Respiratory syncytial virus‐induced exaggeration of allergic airway disease is dependent upon CCR1‐associated immune responses , 2005, European journal of immunology.
[29] S. Johnston,et al. The September epidemic of asthma exacerbations in children: A search for etiology , 2004, Journal of Allergy and Clinical Immunology.
[30] William W Busse,et al. Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial , 2003, The Lancet.
[31] P. Gibson,et al. Neutrophil degranulation and cell lysis is associated with clinical severity in virus-induced asthma , 2002, European Respiratory Journal.
[32] E. Gelfand,et al. IL‐5‐induced airway eosinophilia – the key to asthma? , 2001, Immunological reviews.
[33] S. Holgate,et al. Effect of inhaled corticosteroids on episodes of wheezing associated with viral infection in school age children: randomised double blind placebo controlled trial , 1997, BMJ.
[34] J. Karlsson,et al. RPR 106541, a novel, airways‐selective glucocorticoid: effects against antigen‐induced CD4+T lymphocyte accumulation and cytokine gene expression in the Brown Norway rat lung , 1997, British journal of pharmacology.
[35] M. Sears,et al. Exacerbations of asthma without sputum eosinophilia. , 1995, Thorax.
[36] Stephen T Holgate,et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children , 1995, BMJ.
[37] K. Nicholson,et al. Respiratory viruses and exacerbations of asthma in adults. , 1993, BMJ.
[38] F. H. Yin,et al. Establishment of a mouse model for human rhinovirus infection. , 1986, The Journal of general virology.
[39] C. Reed,et al. Viruses as precipitants of asthmatic attacks in children. , 1974, JAMA.
[40] H. Lambert,et al. Infective Factors in Exacerbations of Bronchitis and Asthma , 1972, British medical journal.