Phase I study of the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of the poly(ADP-ribose) polymerase (PARP) inhibitor veliparib (ABT-888; V) in combination with irinotecan (CPT-11; Ir) in patients (pts) with advanced solid tumors.
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E. Sausville | G. Shapiro | P. LoRusso | R. Parchment | L. Heilbrun | S. Boerner | J. Ji | J. Li | D. W. Smith | M. Pilat | J. Zhang | A. Chen | N. Nechiporchik