Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques
暂无分享,去创建一个
R. Siliciano | G. Alter | D. Barouch | S. Fischinger | E. Borducchi | P. Abbink | J. Nkolola | A. Chandrashekar | N. Mercado | Joseph P. Nkolola | K. McMahan | Anthony M. Cadena | Po-Ting Liu | S. Shin | John D. Ventura | Mithra Kumar | E. Bondzie | Venous Hamza | Nicole Kordana | M. Siamatu | Hubert Tuyishime | Victoria E Walker-Sperling | M. Lewis | E. Fray | Mithra R Kumar | Sally A. Shin
[1] B. Sherman,et al. Defective HIV-1 proviruses produce viral proteins , 2020, Proceedings of the National Academy of Sciences.
[2] S. Gianella,et al. HIV persists throughout deep tissues with repopulation from multiple anatomical sources. , 2020, The Journal of clinical investigation.
[3] Nancy R. Zhang,et al. Elite control of HIV is associated with distinct functional and transcriptional signatures in lymphoid tissue CD8+ T cells , 2019, Science Translational Medicine.
[4] S. Hughes,et al. HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy. , 2019, The Journal of clinical investigation.
[5] K. Reimann,et al. Lack of therapeutic efficacy of an antibody to α4β7 in SIVmac251-infected rhesus macaques , 2019, Science.
[6] P. Lemey,et al. HIV Rebound Is Predominantly Fueled by Genetically Identical Viral Expansions from Diverse Reservoirs. , 2019, Cell host & microbe.
[7] R. Siliciano,et al. The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections. , 2019, Cell host & microbe.
[8] G. Alter,et al. A versatile high-throughput assay to characterize antibody-mediated neutrophil phagocytosis , 2019, Journal of immunological methods.
[9] S. Migueles,et al. Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion , 2019, Nature Communications.
[10] B. Foley,et al. Persistent Viral Reservoirs in Lymphoid Tissues in SIV-Infected Rhesus Macaques of Chinese-Origin on Suppressive Antiretroviral Therapy , 2019, Viruses.
[11] R. Siliciano,et al. A novel quantitative approach for measuring the reservoir of latent HIV-1 proviruses , 2019, Nature.
[12] M. Robb,et al. Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy , 2018, Nature Communications.
[13] S. Lewin,et al. Functional cure of HIV: the scale of the challenge , 2018, Nature Reviews Immunology.
[14] G. Alter,et al. Antibody and TLR7 Agonist Delay Viral Rebound in SHIV-Infected Monkeys , 2018, Nature.
[15] L. Picker,et al. Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound , 2018, Nature Medicine.
[16] R. Schinazi,et al. Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques , 2018, Journal of Virology.
[17] G. Alter,et al. Immune Correlate-Guided HIV Vaccine Design. , 2018, Cell host & microbe.
[18] E. Wherry,et al. Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue , 2018, Science Immunology.
[19] M. Paiardini,et al. Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies , 2018, Front. Immunol..
[20] R. Ribeiro,et al. Dynamics of Simian Immunodeficiency Virus Two-Long-Terminal-Repeat Circles in the Presence and Absence of CD8+ Cells , 2018, Journal of Virology.
[21] G. Alter,et al. Systems serology: profiling vaccine induced humoral immunity against HIV , 2017, Retrovirology.
[22] R. Koup,et al. HIV-Specific CD8+ T Cells Exhibit Reduced and Differentially Regulated Cytolytic Activity in Lymphoid Tissue , 2017, Cell reports.
[23] J. Lifson,et al. Defining total-body AIDS-virus burden with implications for curative strategies , 2017, Nature Medicine.
[24] B. Korber,et al. Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail , 2017, Science Translational Medicine.
[25] Mario Roederer,et al. Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques , 2017, Science.
[26] J. Mellors,et al. Single-cell analysis of HIV-1 transcriptional activity reveals expression of proviruses in expanded clones during ART , 2017, Proceedings of the National Academy of Sciences.
[27] M. Nussenzweig,et al. Early antibody therapy can induce long-lasting immunity to SHIV , 2017, Nature.
[28] Ben Murrell,et al. Antibody 10-1074 suppresses viremia in HIV-1-infected individuals , 2017, Nature Medicine.
[29] G. Alter,et al. Systems serology for evaluation of HIV vaccine trials , 2017, Immunological reviews.
[30] Jeffrey M. Gerold,et al. Ad26/MVA Therapeutic Vaccination with TLR7 Stimulation in SIV-Infected Rhesus Monkeys , 2016, Nature.
[31] B. Walker,et al. Single-Cell Characterization of Viral Translation-Competent Reservoirs in HIV-Infected Individuals. , 2016, Cell host & microbe.
[32] J. Lifson,et al. Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys , 2016, Cell.
[33] R. Siliciano,et al. HIV reservoirs: what, where and how to target them , 2015, Nature Reviews Microbiology.
[34] M. Lederman,et al. Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses That Are Transcriptionally Active before Stopping of Antiretroviral Therapy , 2015, Journal of Virology.
[35] Jerome H. Kim,et al. Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology , 2015, Cell.
[36] R. Siliciano,et al. The Remarkable Stability of the Latent Reservoir for HIV-1 in Resting Memory CD4+ T Cells. , 2015, The Journal of infectious diseases.
[37] Michael S. Seaman,et al. Viraemia suppressed in HIV-1-infected humans by broadly neutralizing antibody 3BNC117 , 2015, Nature.
[38] J. Hoxie,et al. Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques , 2015, Nature Methods.
[39] Jennifer A. Johnson,et al. Induction of HIV-1-specific mucosal immune responses following intramuscular recombinant adenovirus serotype 26 HIV-1 vaccination of humans. , 2015, The Journal of infectious diseases.
[40] G. Silvestri,et al. Persistence of Virus Reservoirs in ART-Treated SHIV-Infected Rhesus Macaques after Autologous Hematopoietic Stem Cell Transplant , 2014, PLoS pathogens.
[41] Jinyan Liu,et al. Rapid Seeding of the Viral Reservoir Prior to SIV Viremia in Rhesus Monkeys , 2014, Nature.
[42] Alan S Perelson,et al. Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues , 2014, Proceedings of the National Academy of Sciences.
[43] Michael S. Seaman,et al. Therapeutic Efficacy of Potent Neutralizing HIV-1-Specific Monoclonal Antibodies in SHIV-Infected Rhesus Monkeys , 2013, Nature.
[44] Jerome H. Kim,et al. Protective Efficacy of a Global HIV-1 Mosaic Vaccine against Heterologous SHIV Challenges in Rhesus Monkeys , 2013, Cell.
[45] Sarah B. Laskey,et al. Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure , 2013, Cell.
[46] Matthew S. Lewis,et al. Immune clearance of highly pathogenic SIV infection , 2013, Nature.
[47] C. Bailey-Kellogg,et al. High-throughput, multiplexed IgG subclassing of antigen-specific antibodies from clinical samples. , 2012, Journal of immunological methods.
[48] Jerome H. Kim,et al. Vaccine Protection Against Acquisition of Neutralization-Resistant SIV Challenges in Rhesus Monkeys , 2011, Nature.
[49] K. Mansfield,et al. Durable Mucosal Simian Immunodeficiency Virus-Specific Effector Memory T Lymphocyte Responses Elicited by Recombinant Adenovirus Vectors in Rhesus Monkeys , 2011, Journal of Virology.
[50] J. Clements,et al. Replication-Competent Simian Immunodeficiency Virus (SIV) Gag Escape Mutations Archived in Latent Reservoirs during Antiretroviral Treatment of SIV-Infected Macaques , 2011, Journal of Virology.
[51] Susan Moir,et al. Pathogenic mechanisms of HIV disease. , 2011, Annual review of pathology.
[52] D. Irvine,et al. A robust, high-throughput assay to determine the phagocytic activity of clinical antibody samples. , 2010, Journal of immunological methods.
[53] Timothy L. Hayes,et al. Viral Sanctuaries during Highly Active Antiretroviral Therapy in a Nonhuman Primate Model for AIDS , 2009, Journal of Virology.
[54] Hui Li,et al. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection , 2008, Proceedings of the National Academy of Sciences.
[55] Qingsheng Li,et al. Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells , 2005, Nature.
[56] Mario Roederer,et al. Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection , 2005, Nature.
[57] J. Clements,et al. The central nervous system is a viral reservoir in simian immunodeficiency virus-infected macaques on combined antiretroviral therapy: A model for human immunodeficiency virus patients on highly active antiretroviral therapy , 2005, Journal of NeuroVirology.
[58] S. Lillard,et al. In-situ sampling and separation of RNA from individual mammalian cells. , 2000, Analytical chemistry.
[59] Anthony S. Fauci,et al. AIDS: Re-emergence of HIV after stopping therapy , 1999, Nature.
[60] J. Lisziewicz,et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy , 1999, Nature Medicine.
[61] K Watanabe,et al. RNA chip: quality assessment of RNA by microchannel linear gel electrophoresis in injection-molded plastic chips. , 1998, Clinical chemistry.
[62] D. Richman,et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. , 1997, Science.
[63] R Brookmeyer,et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. , 1997, Science.
[64] A. Haase,et al. Simian immunodeficiency virus burden in tissues and cellular compartments during clinical latency and AIDS. , 1997, The Journal of infectious diseases.
[65] R. Siliciano,et al. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection , 1997, Nature.
[66] Alan S. Perelson,et al. Quantitative Image Analysis of HIV-1 Infection in Lymphoid Tissue , 1996, Science.
[67] Steven Wolinsky,et al. Analysis of human immunodeficiency virus-infected tissues by amplification and in situ hybridization reveals latent and permissive infections at single-cell resolution. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[68] A. Fauci,et al. Lymphoid organs function as major reservoirs for human immunodeficiency virus. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[69] V. Gallo,et al. Glutamate as a Putative Transmitter in the Cerebellum: Stimulation by GABA of Glutamic Acid Release from Specific Pools , 1981, Journal of neurochemistry.
[70] J. Merrill. Hazards of ethacrynic acid. , 1970, Journal of the American Medical Association (JAMA).
[71] Alan S. Perelson,et al. The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy , 2000, Nature Medicine.
[72] A. Haase,et al. Population biology of HIV-1 infection: viral and CD4+ T cell demographics and dynamics in lymphatic tissues. , 1999, Annual review of immunology.
[73] O. Vejbora. [Changes in reactivity of experimental animals with delayed type of hypersensitivity]. , 1968, Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove.