Genetically predisposed offspring with schizotypal features: An ultra high-risk group for schizophrenia?

[1]  M. Keshavan,et al.  Premorbid characterization in schizophrenia: the Pittsburgh High Risk Study. , 2004, World psychiatry : official journal of the World Psychiatric Association.

[2]  M. Keshavan,et al.  Approaches for adolescents with an affected family member with schizophrenia , 2004, Current psychiatry reports.

[3]  Hok Pan Yuen,et al.  Risk factors for psychosis in an ultra high-risk group: psychopathology and clinical features , 2004, Schizophrenia Research.

[4]  L. Siever,et al.  The pathophysiology of schizophrenia disorders: perspectives from the spectrum. , 2004, The American journal of psychiatry.

[5]  I. Gottesman,et al.  The endophenotype concept in psychiatry: etymology and strategic intentions. , 2003, The American journal of psychiatry.

[6]  Deanna Greenstein,et al.  Structural brain MRI abnormalities in healthy siblings of patients with childhood-onset schizophrenia. , 2003, The American journal of psychiatry.

[7]  S. Lawrie,et al.  The Edinburgh High Risk Study: current status and future prospects. , 2003, World psychiatry : official journal of the World Psychiatric Association.

[8]  S. Lawrie,et al.  What does the Edinburgh high-risk study tell us about schizophrenia? , 2002, American journal of medical genetics.

[9]  Beatriz Luna,et al.  A preliminary functional magnetic resonance imaging study in offspring of schizophrenic parents , 2002, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[10]  Karl J. Friston,et al.  Distributional Assumptions in Voxel-Based Morphometry , 2002, NeuroImage.

[11]  B. Cornblatt,et al.  Wisconsin Card Sorting deficits in the offspring of schizophrenics in the New York High-Risk Project , 2002, Schizophrenia Research.

[12]  Eve C. Johnstone,et al.  Structural Gray Matter Differences between First-Episode Schizophrenics and Normal Controls Using Voxel-Based Morphometry , 2002, NeuroImage.

[13]  D. Braff,et al.  Endophenotyping schizotypy: a prelude to genetic studies within the schizophrenia spectrum , 2002, Schizophrenia Research.

[14]  Marc Laruelle,et al.  Cognitive and brain function in schizotypal personality disorder , 2002, Schizophrenia Research.

[15]  S. Lawrie,et al.  Schizotypal components in people at high risk of developing schizophrenia: early findings from the Edinburgh High-Risk Study , 2002, British Journal of Psychiatry.

[16]  J. Sweeney,et al.  Oculomotor Delayed Response Abnormalities in Young Offspring and Siblings at Risk for Schizophrenia , 2001, CNS Spectrums.

[17]  J. Daléry,et al.  WCST performance and schizotypal features in the first-degree relatives of patients with schizophrenia , 2001, Psychiatry Research.

[18]  R. Straub,et al.  Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[19]  S. Lawrie,et al.  Brain structure, genetic liability, and psychotic symptoms in subjects at high risk of developing schizophrenia , 2001, Biological Psychiatry.

[20]  N. Minshew,et al.  Maturation of Widely Distributed Brain Function Subserves Cognitive Development , 2001, NeuroImage.

[21]  M. Lenzenweger,et al.  Reaction time slowing during high-load, sustained-attention task performance in relation to psychometrically identified schizotypy. , 2001, Journal of abnormal psychology.

[22]  S Marenco,et al.  The neurodevelopmental hypothesis of schizophrenia: Following a trail of evidence from cradle to grave , 2000, Development and Psychopathology.

[23]  Larry J Seidman,et al.  Neuropsychologic functioning among the nonpsychotic relatives of schizophrenic patients: the effect of genetic loading , 2000, Biological Psychiatry.

[24]  Karl J. Friston,et al.  Voxel-Based Morphometry—The Methods , 2000, NeuroImage.

[25]  R. McCarley,et al.  Verbal and nonverbal neuropsychological test performance in subjects with schizotypal personality disorder. , 2000, The American journal of psychiatry.

[26]  A. Sereno,et al.  Schizotypal traits, attention and eye movements , 2000, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[27]  Margaret Niznikiewicz,et al.  The effect of family status and schizotypy on electrophysiologic measures of attention and semantic processing , 2000, Biological Psychiatry.

[28]  B. Cornblatt,et al.  Cognitive and behavioral precursors of schizophrenia , 1999, Development and Psychopathology.

[29]  S. Faraone,et al.  Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a 4-year follow-up study. , 1999, Journal of abnormal psychology.

[30]  S. Hirsch,et al.  Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia , 1998, Journal of neurology, neurosurgery, and psychiatry.

[31]  P. Holzman,et al.  Antisaccades and smooth pursuit eye tracking and schizotypy. , 1998, Archives of general psychiatry.

[32]  M. Mesulam,et al.  From sensation to cognition. , 1998, Brain : a journal of neurology.

[33]  J. John Mann,et al.  Prefrontal and Cerebellar Abnormalities in Major Depression: Evidence from Oculomotor Studies , 1998, Biological Psychiatry.

[34]  S. Faraone,et al.  Factor structure of the Wisconsin Card Sorting Test: dimensions of deficit in schizophrenia. , 1998, Neuropsychology.

[35]  Sohee Park,et al.  Working memory and the syndromes of schizotypal personality , 1997, Schizophrenia Research.

[36]  N. Ryan,et al.  Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): initial reliability and validity data. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[37]  D. Lewis,et al.  Development of the Prefrontal Cortex during Adolescence: Insights into Vulnerable Neural Circuits in Schizophrenia , 1997, Neuropsychopharmacology.

[38]  Paul J. Harrison.  Schizophrenia: a disorder of neurodevelopment? , 1997, Current Opinion in Neurobiology.

[39]  D. Levy,et al.  Thought disorder, perceptual aberrations, and schizotypy. , 1996, Journal of abnormal psychology.

[40]  P S Goldman-Rakic,et al.  Spatial working memory deficits in the relatives of schizophrenic patients. , 1995, Archives of general psychiatry.

[41]  P. Goldman-Rakic,et al.  Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17. , 1995, Archives of general psychiatry.

[42]  I. Gottesman,et al.  The New York High-Risk Project. Psychoses and cluster A personality disorders in offspring of schizophrenic parents at 23 years of follow-up. , 1995, Archives of general psychiatry.

[43]  C. Frith,et al.  Functional imaging and cognitive abnormalities , 1995, The Lancet.

[44]  S. Faraone,et al.  Neuropsychological functioning among the nonpsychotic relatives of schizophrenic patients: a diagnostic efficiency analysis. , 1995, Journal of abnormal psychology.

[45]  S. Anderson,et al.  Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited. , 1994, Journal of psychiatric research.

[46]  K. Kendler,et al.  The Roscommon Family Study. III. Schizophrenia-related personality disorders in relatives. , 1993, Archives of general psychiatry.

[47]  N C Andreasen,et al.  Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London. , 1992, Archives of general psychiatry.

[48]  G. Reynolds,et al.  Pre-frontal structural and functional deficits associated with individual differences in schizotypal personality , 1992, Schizophrenia Research.

[49]  K O Lim,et al.  Widespread cerebral gray matter volume deficits in schizophrenia. , 1992, Archives of general psychiatry.

[50]  F. Vogel,et al.  Schizophrenia genesis: The origins of madness , 1991 .

[51]  B. Cornblatt,et al.  Schizotypy and sustained attention. , 1991, Journal of abnormal psychology.

[52]  L. Siever,et al.  Increased morbid risk for schizophrenia-related disorders in relatives of schizotypal personality disordered patients. , 1990, Archives of general psychiatry.

[53]  P. Ambrosini,et al.  Videotape reliability of the third revised edition of the K-SADS. , 1989, Journal of the American Academy of Child and Adolescent Psychiatry.

[54]  R. Murray,et al.  Is schizophrenia a neurodevelopmental disorder? , 1987, British medical journal.

[55]  D. Weinberger.  Implications of normal brain development for the pathogenesis of schizophrenia. , 1987, Archives of general psychiatry.

[56]  L. J. Chapman,et al.  Magical ideation as an indicator of schizotypy. , 1983, Journal of consulting and clinical psychology.

[57]  P. Møller,et al.  Progress in neuro-psychopharmacology & biological psychiatry , 1982, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[58]  Richard J. Haier,et al.  Schizophrenia: The epigenetic puzzle Cambridge University Press, Cambridge (1982). 258 pp. by Irving I. Gottesman and James Shields , 1982, Psychiatry Research.

[59]  P. L. Randall.  A neuroanatomical theory on the aetiology of schizophrenia. , 1980, Medical hypotheses.

[60]  Paul J. Harrison,et al.  Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence , 2005, Molecular Psychiatry.

[61]  C. Curtis,et al.  Multiple dimensions of schizotypy in first degree biological relatives of schizophrenia patients. , 2004, Schizophrenia bulletin.

[62]  C. Stefanis,et al.  Higher scores of self reported schizotypy in healthy young males carrying the COMT high activity allele , 2002, Molecular Psychiatry.

[63]  H. Coon,et al.  Ocular motor delayed-response task performance among patients with schizophrenia and their biological relatives. , 2001, Psychophysiology.

[64]  J. Sweeney,et al.  Studies of brain and cognitive maturation through childhood and adolescence: a strategy for testing neurodevelopmental hypotheses. , 2001, Schizophrenia bulletin.

[65]  D. Lewis,et al.  Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. , 2000, Archives of general psychiatry.

[66]  A D Paterson,et al.  Schizophrenia: an epigenetic puzzle? , 1999, Schizophrenia bulletin.

[67]  D. Lewis.  Schizophrenia and disordered neural circuitry. , 1997, Schizophrenia bulletin.

[68]  Tyrone D. Cannon,et al.  Structural brain abnormalities as indicators of vulnerability to schizophrenia. , 1994, Schizophrenia bulletin.

[69]  L. J. Chapman,et al.  The search for symptoms predictive of schizophrenia. , 1987, Schizophrenia bulletin.

[70]  Barbara A. Cornblatt,et al.  The New York High-Risk Project. , 1984 .

[71]  L. J. Chapman,et al.  Scales for rating psychotic and psychotic-like experiences as continua. , 1980, Schizophrenia bulletin.