Alder Ene Reaction

The Alder ene reaction, also known as the hydro-allyl addition, is addition of an enophile to an alkene (ene) via allylic transposition. The four-electron system including an alkene π-bond and an allylic C–H σ-bond can participate in a pericyclic reaction in which the double bond shifts and new C–H and C–C σ-bonds are formed.

[1]  Y. Endo,et al.  Enantiocontrolled synthesis of jasmonates via tandem retro-Diels-Alder-ene reaction activated by a silyl substituent. , 2004, Organic letters.

[2]  Andrew G. Leach,et al.  Diels-Alder and ene reactions of singlet oxygen, nitroso compounds and triazolinediones: transition states and mechanisms from contemporary theory. , 2002, Chemical communications.

[3]  Xumu Zhang,et al.  Highly Enantioselective Syntheses of Functionalized α-Methylene-γ-butyrolactones via Rh(I)-catalyzed Intramolecular Alder Ene Reaction: Application to Formal Synthesis of (+)-Pilocarpine , 2002 .

[4]  K. Takagi,et al.  Rhodium complex-catalyzed intramolecular ene-type reaction of allenynes , 2003 .

[5]  J. S. Johnson,et al.  Chiral bis(oxazoline) copper(II) complexes: versatile catalysts for enantioselective cycloaddition, Aldol, Michael, and carbonyl ene reactions. , 2000, Accounts of chemical research.

[6]  W. Oppolzer.  Asymmetrische Diels‐Alder‐ und En‐Reaktionen in der Organischen Synthese , 1984 .

[7]  Manfred Regitz,et al.  The Ene Reaction in the Chemistry of Low-Coordinate Phosphorus , 1998 .

[8]  W. Oppolzer.  Regio- and stereo-selective syntheses of cyclic natural products by intramolecular cycloaddition- and ene-reactions , 1981 .

[9]  M. Orfanopoulos,et al.  Tetrahedron Report Number 519 Regioselectivity in the Ene Reaction of Singlet Oxygen with Alkenes , 2000 .

[10]  A. Schmitz,et al.  Über die Anlagerung von Maleinsäure‐anhydrid und Azodicarbonsäure‐ester an einfach ungesättigte Koh an einfach ungesättigte Kohlenwasserstoffe. Zur Kenntnis von Substitutionsvorgängen in der Allyl‐Stellung , 1943 .