Sustainable return to work among breast cancer survivors.

PURPOSE This study assessed sustainable return to work (SRTW) of breast cancer survivors (BCS). METHODS We used data from the prospective French cohort, CANTO. We included 1811 stage I-III BCS who were <57 years old and employed at the moment of diagnosis and working 2 years after diagnosis. Using logistic regression, we investigated the role of clinical, health and socio-economic factors, and the work environment on SRTW 3 years after diagnosis. We compared having any sick leave with having worked continuously and being unemployed to having worked continuously between 2 and 3 years after diagnosis. RESULTS Overall, 77% (n = 1395) worked continuously after return to work (RTW). Out of the other 416 BCS, 66% had any sick leave period, 33% had been unemployed, 4% had an early retirement, 2% a disability and 1% another status (multiple situations possible). Being on sick leave was associated with age > 50 (OR = 0.59; 95%CI = 0.43-0.82), stage III (2.56; 1.70-3.85), tumour subtype HR+/HER2+ (0.61; 0.39-0.95), severe fatigue (1.45; 1.06-1.98), workplace accommodations (1.63; 1.14-2.33) and life priorities (0.71; 0.53-0.95). Unemployment was associated with age > 50 (0.45; 0.29-0.72), working in the public sector (0.31; 0.19-0.51), for a small company (3.00; 1.74-5.20) and having a fixed-term contract (7.50; 4.74-11.86). CONCLUSIONS A high number of BCS have periods of sick leave or unemployment after RTW. The determinants differ between sick leave and unemployment. IMPLICATIONS FOR CANCER SURVIVORS BCS need to be supported even after RTW, which should be regarded as a process.

[1]  R. Rouzier,et al.  Perceived discrimination at work: examining social, health and work-related factors as determinants among breast cancer survivors – evidence from the prospective CANTO cohort , 2022, Journal of Epidemiology & Community Health.

[2]  Juhee Cho,et al.  Changes in working status after cancer diagnosis and socio-demographic, clinical, work-related, and psychological factors associated with it , 2022, BMC cancer.

[3]  M. Ewertz,et al.  Work status changes and associated factors in a nationwide sample of Norwegian long-term breast cancer survivors , 2022, Journal of Cancer Survivorship.

[4]  C. Coutant,et al.  Change in the value of work after breast cancer: evidence from a prospective cohort , 2022, Journal of Cancer Survivorship.

[5]  K. Alexanderson,et al.  Factors of decisive importance for being in work or not during two years after breast cancer surgery: content analysis of 462 women’s open answers , 2021, BMC Women's Health.

[6]  F. Benavides,et al.  Returning to work after a sickness absence due to cancer: a cohort study of salaried workers in Catalonia (Spain) , 2021, Scientific Reports.

[7]  M. Lambe,et al.  Impact of chemotherapy, radiotherapy, and endocrine therapy on sick leave in women with early-stage breast cancer during a 5-year period: a population-based cohort study , 2020, Breast Cancer Research and Treatment.

[8]  V. Zadnik,et al.  Long-term work retention after treatment for cancer: a systematic review and meta-analysis , 2020, Journal of Cancer Survivorship.

[9]  A. Paraponaris,et al.  The positive effect of workplace accommodations on the continued employment of cancer survivors five years after diagnosis , 2020, Supportive Care in Cancer.

[10]  M. Bendiane,et al.  Inequality in income change among cancer survivors five years after diagnosis: Evidence from a French national survey , 2019, PloS one.

[11]  F. André,et al.  UNICANCER: French prospective cohort study of treatment-related chronic toxicity in women with localised breast cancer (CANTO) , 2019, ESMO Open.

[12]  L. Holmberg,et al.  Causes of sick leave, disability pension, and death following a breast cancer diagnosis in women of working age. , 2019, Breast.

[13]  U. Bültmann,et al.  Work functioning trajectories in cancer patients: Results from the longitudinal Work Life after Cancer (WOLICA) study , 2017, International journal of cancer.

[14]  M. Frings-Dresen,et al.  Return to work of cancer patients after a multidisciplinary intervention including occupational counselling and physical exercise in cancer patients: a prospective study in the Netherlands , 2017, BMJ Open.

[15]  A. Paraponaris,et al.  Transitions in the labor market after cancer: a comparison of self-employed workers and salaried staff , 2016, Supportive Care in Cancer.

[16]  N. Aaronson,et al.  Thresholds for clinical importance for four key domains of the EORTC QLQ-C30: physical functioning, emotional functioning, fatigue and pain , 2016, Health and Quality of Life Outcomes.

[17]  B. Kirsh,et al.  The provision of workplace accommodations following cancer: survivor, provider, and employer perspectives , 2016, Journal of Cancer Survivorship.

[18]  J. Jones,et al.  Qualitative meta-synthesis of survivors’ work experiences and the development of strategies to facilitate return to work , 2014, Journal of Cancer Survivorship.

[19]  Rusan Chen,et al.  Function and friction at work: a multidimensional analysis of work outcomes in cancer survivors , 2014, Journal of Cancer Survivorship.

[20]  T. Kroll,et al.  Supporting ‘work‐related goals’ rather than ‘return to work’ after cancer? A systematic review and meta‐synthesis of 25 qualitative studies , 2013, Psycho-oncology.

[21]  Stef van Buuren,et al.  MICE: Multivariate Imputation by Chained Equations in R , 2011 .

[22]  A. Paraponaris,et al.  Job tenure and self-reported workplace discrimination for cancer survivors 2 years after diagnosis: does employment legislation matter? , 2010, Health policy.

[23]  M. Hahm,et al.  Changes in employment status and experience of discrimination among cancer patients: findings from a nationwide survey in Korea , 2010, Psycho-oncology.

[24]  K. Alexanderson,et al.  Predictors of return to work ten months after primary breast cancer surgery , 2009, Acta oncologica.

[25]  Jae-Hyun Park,et al.  Job loss and re-employment of cancer patients in Korean employees: a nationwide retrospective cohort study. , 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[26]  B. Jönsson,et al.  Cost of breast cancer in Sweden in 2002 , 2007, The European Journal of Health Economics.

[27]  R. Snaith,et al.  The Hospital Anxiety And Depression Scale , 2003, Health and quality of life outcomes.

[28]  A. Paraponaris,et al.  Continuous-Time Markov Model for Transitions Between Employment and Non-Employment: The Impact of a Cancer Diagnosis , 2012 .

[29]  J. Hurley,et al.  Workplace discrimination and cancer. , 2007, Work.