Antiproliferative and cytotoxic effects of green coffee and yerba mate extracts, their main hydroxycinnamic acids, methylxanthine and metabolites in different human cell lines.

[1]  Shaokang Wang,et al.  Tea consumption and risk of breast cancer: A meta-analysis. , 2018, International journal of clinical pharmacology and therapeutics.

[2]  B. Sarriá,et al.  Improved LC-MSn characterization of hydroxycinnamic acid derivatives and flavonols in different commercial mate (Ilex paraguariensis) brands. Quantification of polyphenols, methylxanthines, and antioxidant activity. , 2018, Food chemistry.

[3]  B. Sarriá,et al.  Exhaustive Qualitative LC-DAD-MSn Analysis of Arabica Green Coffee Beans: Cinnamoyl-glycosides and Cinnamoylshikimic Acids as New Polyphenols in Green Coffee. , 2016, Journal of agricultural and food chemistry.

[4]  B. Sarriá,et al.  Dihydrocaffeic acid, a major microbial metabolite of chlorogenic acids, shows similar protective effect than a yerba mate phenolic extract against oxidative stress in HepG2 cells. , 2016, Food research international.

[5]  S. Mun,et al.  Pinus radiata bark extract induces caspase-independent apoptosis-like cell death in MCF-7 human breast cancer cells , 2016, Cell Biology and Toxicology.

[6]  T. Stępkowski,et al.  The role of natural polyphenols in cell signaling and cytoprotection against cancer development. , 2016, The Journal of nutritional biochemistry.

[7]  N. Tajeddine.  How do reactive oxygen species and calcium trigger mitochondrial membrane permeabilisation? , 2016, Biochimica et biophysica acta.

[8]  Y. Gan,et al.  Association of coffee consumption with risk of colorectal cancer: a meta-analysis of prospective cohort studies , 2016, OncoTarget.

[9]  S. Gruber,et al.  Coffee Consumption and the Risk of Colorectal Cancer , 2016, Cancer Epidemiology, Biomarkers & Prevention.

[10]  Lingjuan Zhu,et al.  Unravelling the relationship between macroautophagy and mitochondrial ROS in cancer therapy , 2016, Apoptosis.

[11]  Xingbin Yang,et al.  Evaluation of antioxidative and antitumor activities of extracted flavonoids from Pink Lady apples in human colon and breast cancer cell lines. , 2015, Food & function.

[12]  Qing Wang,et al.  Corrigendum: Magmatic record of India-Asia collision , 2015, Scientific Reports.

[13]  J. Fichna,et al.  Polyphenols as mitochondria-targeted anticancer drugs. , 2015, Cancer letters.

[14]  W. Willett,et al.  Coffee Intake, Recurrence, and Mortality in Stage III Colon Cancer: Results From CALGB 89803 (Alliance). , 2015, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[15]  Y. Tong,et al.  Coffee consumption and bladder cancer: a meta-analysis of observational studies , 2015, Scientific Reports.

[16]  F. Clavel-Chapelon,et al.  Coffee and tea consumption and risk of pre- and postmenopausal breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study , 2015, Breast Cancer Research.

[17]  B. Keller,et al.  The use of the Gail model, body mass index and SNPs to predict breast cancer among women with abnormal (BI-RADS 4) mammograms , 2015, Breast Cancer Research.

[18]  Jiangbo Chen,et al.  Tea and Coffee Consumption and Risk of Laryngeal Cancer: A Systematic Review Meta-Analysis , 2014, PloS one.

[19]  B. Ozpolat,et al.  Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer , 2014, Cell Death and Disease.

[20]  B. Sarriá,et al.  Pharmacokinetics of caffeine and its metabolites in plasma and urine after consuming a soluble green/roasted coffee blend by healthy subjects. , 2014, Food research international.

[21]  E. Riboli,et al.  Tea and coffee consumption and risk of esophageal cancer: The European prospective investigation into cancer and nutrition study , 2014, International journal of cancer.

[22]  B. Sarriá,et al.  Green coffee hydroxycinnamic acids but not caffeine protect human HepG2 cells against oxidative stress , 2014 .

[23]  R. Blomhoff,et al.  Coffee and cancer risk, epidemiological evidence, and molecular mechanisms. , 2014, Molecular nutrition & food research.

[24]  L. Marabini,et al.  Protective effect of Vaccinium myrtillus extract against UVA- and UVB-induced damage in a human keratinocyte cell line (HaCaT cells). , 2014, Journal of photochemistry and photobiology. B, Biology.

[25]  J. Andrici,et al.  Maté consumption and the risk of esophageal squamous cell carcinoma: a meta-analysis. , 2013, Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus.

[26]  H. Hauner,et al.  Bioappearance and pharmacokinetics of bioactives upon coffee consumption , 2013, Analytical and Bioanalytical Chemistry.

[27]  C. Peng,et al.  Cytotoxicity of Ferulic Acid on T24 Cell Line Differentiated by Different Microenvironments , 2013, BioMed research international.

[28]  P. Kroon,et al.  Anticancer activity of olive oil hydroxytyrosyl acetate in human adenocarcinoma Caco-2 cells. , 2013, Journal of agricultural and food chemistry.

[29]  M. A. Martín,et al.  Chemo-protective activity and characterization of phenolic extracts from Corema album , 2012 .

[30]  Patricia Esquivel,et al.  Functional properties of coffee and coffee by-products , 2012 .

[31]  C. la Vecchia,et al.  A meta-analysis of coffee consumption and pancreatic cancer. , 2012, Annals of oncology : official journal of the European Society for Medical Oncology.

[32]  L. Goya,et al.  Cocoa-rich diet prevents azoxymethane-induced colonic preneoplastic lesions in rats by restraining oxidative stress and cell proliferation and inducing apoptosis. , 2011, Molecular nutrition & food research.

[33]  L. Goya,et al.  Dietary flavanols exert different effects on antioxidant defenses and apoptosis/proliferation in Caco-2 and SW480 colon cancer cells. , 2011, Toxicology in Vitro.

[34]  M. Berhow,et al.  Dicaffeoylquinic acids in Yerba mate (Ilex paraguariensis St. Hilaire) inhibit NF-κB nucleus translocation in macrophages and induce apoptosis by activating caspases-8 and -3 in human colon cancer cells. , 2011, Molecular nutrition & food research.

[35]  A. Gugliucci,et al.  Recent advances on Ilex paraguariensis research: minireview. , 2011, Journal of ethnopharmacology.

[36]  P. Kroon,et al.  Transepithelial transport and metabolism of new lipophilic ether derivatives of hydroxytyrosol by enterocyte-like Caco-2/TC7 cells. , 2010, Journal of agricultural and food chemistry.

[37]  G. Williamson,et al.  Bioavailability of chlorogenic acids following acute ingestion of coffee by humans with an ileostomy. , 2010, Archives of biochemistry and biophysics.

[38]  P. Brennan,et al.  Drinking of maté and the risk of cancers of the upper aerodigestive tract in Latin America: a case–control study , 2010, Cancer Causes & Control.

[39]  A. Dasanayake,et al.  Maté drinking and oral and oro-pharyngeal cancer: a systematic review and meta-analysis. , 2010, Oral oncology.

[40]  L. F. Barbisan,et al.  Chemopreventive effects of mate against mouse mammary and colon carcinogenesis. , 2010, Human & experimental toxicology.

[41]  L. Goya,et al.  A diet rich in cocoa attenuates N-nitrosodiethylamine-induced liver injury in rats. , 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[42]  G. Bartosz,et al.  Evaluation of the cyto- and genotoxic activity of yerba mate (Ilex paraguariensis) in human lymphocytes in vitro. , 2009, Mutation research.

[43]  Su-zhan Zhang,et al.  Ursolic acid inhibits proliferation and induces apoptosis of HT-29 colon cancer cells by inhibiting the EGFR/MAPK pathway , 2009, Journal of Zhejiang University SCIENCE B.

[44]  M. Suzui,et al.  Growth inhibitory activity of ethanol extracts of Chinese and Brazilian propolis in four human colon carcinoma cell lines. , 2009, Oncology reports.

[45]  D. Salvadori,et al.  Maté attenuates DNA damage and carcinogenesis induced by diethylnitrosamine and thermal injury in rat esophagus. , 2009, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[46]  R. Zanetti,et al.  Cancer and yerba mate consumption: a review of possible associations. , 2009, Revista panamericana de salud publica = Pan American journal of public health.

[47]  A. Nkondjock.  Coffee consumption and the risk of cancer: an overview. , 2009, Cancer letters.

[48]  Bin Wang,et al.  Coffee consumption and risk of breast cancer: a metaanalysis. , 2009, American journal of obstetrics and gynecology.

[49]  M. Angeles Martín,et al.  Time-course regulation of survival pathways by epicatechin on HepG2 cells. , 2009, The Journal of nutritional biochemistry.

[50]  S. Tsugane,et al.  Coffee, green tea, and caffeine consumption and subsequent risk of bladder cancer in relation to smoking status: a prospective study in Japan , 2009, Cancer science.

[51]  S. Lafay,et al.  Chlorogenic acids from green coffee extract are highly bioavailable in humans. , 2008, The Journal of nutrition.

[52]  M. Ribeiro,et al.  Protective effects of mate tea (Ilex paraguariensis) on H2O2-induced DNA damage and DNA repair in mice. , 2008, Mutagenesis.

[53]  S. Ramos.  Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways. , 2008, Molecular nutrition & food research.

[54]  M. Angeles Martín,et al.  Time-course regulation of quercetin on cell survival/proliferation pathways in human hepatoma cells. , 2008, Molecular nutrition & food research.

[55]  M. Inoue,et al.  Coffee consumption and risk of endometrial cancer: A prospective study in Japan , 2008, International journal of cancer.

[56]  A. Cardinali,et al.  Antioxidative and Apoptotic Properties of Polyphenolic Extracts from Edible Part of Artichoke (Cynara scolymus L.) on Cultured Rat Hepatocytes and on Human Hepatoma Cells , 2008, Nutrition and cancer.

[57]  J. Kanno,et al.  Evaluation of Action Mechanisms of Toxic Chemicals Using JFCR39, a Panel of Human Cancer Cell Lines , 2007, Molecular Pharmacology.

[58]  D. Perrone,et al.  Chlorogenic acid compounds from coffee are differentially absorbed and metabolized in humans. , 2007, The Journal of nutrition.

[59]  L. Goya,et al.  LC/MS characterization of phenolic constituents of mate (Ilex paraguariensis, St. Hil.) and its antioxidant activity compared to commonly consumed beverages , 2007 .

[60]  P. Boffetta,et al.  Non-alcoholic beverages and risk of bladder cancer in Uruguay , 2007, BMC Cancer.

[61]  M. Bates,et al.  Bladder cancer and mate consumption in Argentina: a case-control study. , 2007, Cancer letters.

[62]  L. Goya,et al.  Molecular mechanisms of (-)-epicatechin and chlorogenic acid on the regulation of the apoptotic and survival/proliferation pathways in a human hepatoma cell line. , 2007, Journal of agricultural and food chemistry.

[63]  M. Yoshimoto,et al.  Growth suppression of human cancer cells by polyphenolics from sweetpotato (Ipomoea batatas L.) leaves. , 2007, Journal of agricultural and food chemistry.

[64]  L. Goya,et al.  Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2). , 2006, The Journal of nutrition.

[65]  N. Habermann,et al.  Bread Enriched With Green Coffee Extract Has Chemoprotective and Antigenotoxic Activities in Human Cells , 2006, Nutrition and cancer.

[66]  L. Goya,et al.  Uptake and metabolism of hydroxycinnamic acids (chlorogenic, caffeic, and ferulic acids) by HepG2 cells as a model of the human liver. , 2006, Journal of agricultural and food chemistry.

[67]  J. Exon,et al.  A Review of the Effects and Mechanisms of Polyphenolics in Cancer , 2006, Critical reviews in food science and nutrition.

[68]  V. Castranova,et al.  Inhibition of Activator Protein-1, NF-κB, and MAPKs and Induction of Phase 2 Detoxifying Enzyme Activity by Chlorogenic Acid* , 2005, Journal of Biological Chemistry.

[69]  A. C. Santos,et al.  The interaction of flavonoids with mitochondria: effects on energetic processes. , 2005, Chemico-biological interactions.

[70]  L. Goya,et al.  Response of the antioxidant defense system to tert‐butyl hydroperoxide and hydrogen peroxide in a human hepatoma cell line (HepG2) , 2005, Journal of biochemical and molecular toxicology.

[71]  H. Babich,et al.  Differential in vitro cytotoxicity of (-)-epicatechin gallate (ECG) to cancer and normal cells from the human oral cavity. , 2005, Toxicology in vitro : an international journal published in association with BIBRA.

[72]  M. Ramírez-Mares,et al.  Effect of yerba mate (Ilex paraguariensis) tea on topoisomerase inhibition and oral carcinoma cell proliferation. , 2005, Journal of agricultural and food chemistry.

[73]  K. Mochida,et al.  In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans. , 2004, Journal of agricultural and food chemistry.

[74]  Thomas Walle,et al.  Cellular Uptake and Efflux of the Tea Flavonoid (-)Epicatechin-3-gallate in the Human Intestinal Cell Line Caco-2 , 2003, Journal of Pharmacology and Experimental Therapeutics.

[75]  Y. Surh,et al.  Cancer chemoprevention with dietary phytochemicals , 2003, Nature Reviews Cancer.

[76]  P. Brennan,et al.  Maté consumption and the risk of squamous cell esophageal cancer in uruguay. , 2003, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[77]  D. Goldenberg.  Maté: a risk factor for oral and oropharyngeal cancer. , 2002, Oral oncology.

[78]  M. Yoshimoto,et al.  Antimutagenicity of Mono-, Di-, and Tricaffeoylquinic Acid Derivatives Isolated from Sweetpotato (Ipomoea batatas L.) Leaf , 2002, Bioscience, biotechnology, and biochemistry.

[79]  E. Giovannucci.  Meta-analysis of coffee consumption and risk of colorectal cancer. , 1998, American journal of epidemiology.

[80]  E. Fontham,et al.  Mate drinking and risk of lung cancer in males: a case-control study from Uruguay. , 1996, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[81]  J. Pintos,et al.  Maté, Coffee, and Tea Consumption and Risk of Cancers of the Upper Aerodigestive Tract in Southern Brazil , 1994, Epidemiology.

[82]  J. Li,et al.  Chlorogenic acid induces reactive oxygen species generation and inhibits the viability of human colon cancer cells , 2017, Anti-cancer drugs.

[83]  T. Velickovic,et al.  The anti-cancer activity of green tea, coffee and cocoa extracts on human cervical adenocarcinoma HeLa cells depends on both pro-oxidant and anti-proliferative activities of polyphenols , 2015 .

[84]  Jingyi Zhang,et al.  Pterostilbene simultaneously induces apoptosis, cell cycle arrest and cyto-protective autophagy in breast cancer cells. , 2012, American journal of translational research.

[85]  Bin Wang,et al.  Coffee consumption and risk of lung cancer: a meta-analysis. , 2010, Lung cancer.

[86]  E. D. de Mejia,et al.  Yerba mate tea (Ilex paraguariensis): Phenolics, antioxidant capacity and in vitro inhibition of colon cancer cell proliferation , 2010 .

[87]  G. Haegeman,et al.  Epicatechin induces NF-kappaB, activator protein-1 (AP-1) and nuclear transcription factor erythroid 2p45-related factor-2 (Nrf2) via phosphatidylinositol-3-kinase/protein kinase B (PI3K/AKT) and extracellular regulated kinase (ERK) signalling in HepG2 cells. , 2010, The British journal of nutrition.

[88]  F. Saura-calixto,et al.  Characterization of Dietary Fiber and the In Vitro Indigestible Fraction of Grape Pomace , 1998, American Journal of Enology and Viticulture.

[89]  J. Everhart,et al.  Diet and mortality from common cancers in Brazil: an ecological study. , 1996, Cadernos de saude publica.

[90]  D. Acosta,et al.  4 – Enzyme Leakage as an Indicator of Cytotoxicity in Cultured Cells , 1994 .