Using Multimodal MR Data for Segmentation and Topology Recovery of the Cerebral Superficial Venous Tree

Magnetic resonance angiography (MRA) produces 3D data visualizing vascular structures by detecting the flowing blood signal. While segmentation methods generally detect vessels by only processing MRA, the proposed method uses both MRA and non-angiographic (MRI) images. It is based on the assumption that MRI provides anatomical information useful for vessel detection. This supplementary information can be used to correct the topology of the segmented vessels. Vessels are first segmented from MRA while the cortex is segmented from MRI. An algorithm, based on distance maps and topology preserving thinning, then uses both segmented structures for recovery of the missing parts of the brain superficial venous tree and removal of other vessels. This method has been performed and validated on 9 MRA/MRI data of the brain. The results show that the venous tree is correctly segmented and topologically recovered with a 84% accuracy.

[1]  Computer-Assisted Intervention,et al.  Medical Image Computing and Computer-Assisted Intervention – MICCAI’99 , 1999, Lecture Notes in Computer Science.

[2]  Nicolas Flasque,et al.  Acquisition, segmentation and tracking of the cerebral vascular tree on 3D magnetic resonance angiography images , 2001, Medical Image Anal..

[3]  Fabrice Heitz,et al.  ImLib3D: An Efficient, Open Source, Medical Image Processing Framework in C++ , 2003, MICCAI.

[4]  Nicolas Passat,et al.  Using Watershed and Multimodal Data for Vessel Segmentation: Application to the Superior Sagittal Sinus , 2005, ISMM.

[5]  Jean-Paul Armspach,et al.  Region‐growing segmentation of brain vessels: An atlas‐based automatic approach , 2005, Journal of magnetic resonance imaging : JMRI.

[6]  Terry M. Peters,et al.  Medical Image Computing and Computer-Assisted Intervention - MICCAI 2003 , 2003, Lecture Notes in Computer Science.

[7]  Francis K. H. Quek,et al.  A review of vessel extraction techniques and algorithms , 2004, CSUR.

[8]  Fabrice Heitz,et al.  Statistical atlas-based sub-voxel segmentation of 3D brain MRI , 2003, Proceedings 2003 International Conference on Image Processing (Cat. No.03CH37429).

[9]  Nicholas Ayache,et al.  Computer Vision, Virtual Reality and Robotics in Medicine , 1995, Lecture Notes in Computer Science.

[10]  Isabelle Bloch,et al.  3D Reconstruction of Blood Vessels by Multi-Modality Data Fusion Using Fuzzy and Markovian Modelling , 1995, CVRMed.

[11]  Christophe Lohou,et al.  Liver Blood Vessels Extraction by a 3-D Topological Approach , 1999, MICCAI.