Multisystem Inflammatory Syndrome in an Adult After COVID-19

Abstract We describe the first case of multisystem inflammatory syndrome in an adult patient after coronavirus disease-19 (COVID-19). A 34-year-old Hispanic man, who tested positive for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) 1 month before presentation, was admitted for fever, abdominal pain, headache, and myalgia. The patient deteriorated, developing multisystem organ failure. He required intensive care unit admission, mechanical ventilation, vasopressors, and continuous renal replacement therapy. Laboratory workup showed depletion of serum complement levels. After immunosuppressive therapy with intravenous immunoglobulin and corticosteroids, complement levels improved, and the patient made a full recovery.