The interferon-α signature of systemic lupus erythematosus
暂无分享,去创建一个
[1] J. G. Hirsch. BACTERICIDAL ACTION OF HISTONE , 1958, The Journal of experimental medicine.
[2] H. Sano,et al. Dna isolated from DNA/anti-DNA antibody immune complexes in systemic lupus erythematosus is rich in guanine-cytosine content. , 1982, Journal of immunology.
[3] R. Friedman,et al. Systemic lupus erythematosus: presence in human serum of an unusual acid-labile leukocyte interferon. , 1982, Science.
[4] L. Rönnblom,et al. Possible induction of systemic lupus erythematosus by interferon‐α treatment in a patient with a malignant carcinoid tumour , 1990, Journal of internal medicine.
[5] A. Rosen,et al. Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes , 1994, The Journal of experimental medicine.
[6] S Askari,et al. A novel role for the beta 2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation. , 1996, Immunity.
[7] J. Banchereau,et al. The Enigmatic Plasmacytoid T Cells Develop into Dendritic Cells with Interleukin (IL)-3 and CD40-Ligand , 1997, The Journal of experimental medicine.
[8] L. Rönnblom,et al. Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-alpha- producing cells. , 1998, Journal of autoimmunity.
[9] Pier Paolo Pandolfi,et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies , 1998, Nature Genetics.
[10] L. Rönnblom,et al. Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus. , 1999, Journal of immunology.
[11] D. Jarrossay,et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon , 1999, Nature Medicine.
[12] N. Kadowaki,et al. The nature of the principal type 1 interferon-producing cells in human blood. , 1999, Science.
[13] L. Rönnblom,et al. Patients with systemic lupus erythematosus (SLE) have a circulating inducer of interferon‐alpha (IFN‐α) production acting on leucocytes resembling immature dendritic cells , 1999, Clinical and experimental immunology.
[14] A. Rosen,et al. Cleavage by Granzyme B Is Strongly Predictive of Autoantigen Status , 1999, The Journal of experimental medicine.
[15] T. Möröy,et al. Features of systemic lupus erythematosus in Dnase1-deficient mice , 2000, Nature Genetics.
[16] C Caux,et al. Immunobiology of dendritic cells. , 2000, Annual review of immunology.
[17] T. Di Pucchio,et al. Type I Interferon as a Powerful Adjuvant for Monocyte-Derived Dendritic Cell Development and Activity in Vitro and in Hu-Pbl-Scid Mice , 2000, The Journal of experimental medicine.
[18] M. Madaio. Major peptide autoepitopes for nucleosome-specific T cells of human lupus. , 2000, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[19] M. Walport,et al. Complement. Second of two parts. , 2001, The New England journal of medicine.
[20] Antonio Lanzavecchia,et al. BDCA-2, a Novel Plasmacytoid Dendritic Cell–specific Type II C-type Lectin, Mediates Antigen Capture and Is a Potent Inhibitor of Interferon α/β Induction , 2001, The Journal of experimental medicine.
[21] L. Rönnblom,et al. A Pivotal Role for the Natural Interferon α–producing Cells (Plasmacytoid Dendritic Cells) in the Pathogenesis of Lupus , 2001, The Journal of experimental medicine.
[22] F. Lund-Johansen,et al. Plasmacytoid dendritic cells (natural interferon- alpha/beta-producing cells) accumulate in cutaneous lupus erythematosus lesions. , 2001, The American journal of pathology.
[23] N. Kadowaki,et al. Subsets of Human Dendritic Cell Precursors Express Different Toll-like Receptors and Respond to Different Microbial Antigens , 2001, The Journal of experimental medicine.
[24] V. Pascual,et al. Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. , 2001, Science.
[25] Virginia Pascual,et al. Induction of Dendritic Cell Differentiation by IFN-α in Systemic Lupus Erythematosus , 2001, Science.
[26] L. Rönnblom,et al. Presence of cutaneous interferon-a producing cells in patients with systemic lupus erythematosus , 2001, Lupus.
[27] V. Pascual,et al. The interplay of dendritic cell subsets in systemic lupus erythematosus , 2002, Immunology and cell biology.
[28] M. Shlomchik,et al. Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors , 2002, Nature.
[29] R. Jonsson,et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans , 2002, Nature Genetics.
[30] Virginia Pascual,et al. Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus Blood , 2003, The Journal of experimental medicine.
[31] J. Dai,et al. Comparative analysis of IRF and IFN‐alpha expression in human plasmacytoid and monocyte‐derived dendritic cells , 2003, Journal of leukocyte biology.
[32] L. Rönnblom,et al. Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG. , 2003, Journal of immunology.
[33] L. Rönnblom,et al. FcγRIIa Is Expressed on Natural IFN-α-Producing Cells (Plasmacytoid Dendritic Cells) and Is Required for the IFN-α Production Induced by Apoptotic Cells Combined with Lupus IgG 1 , 2003, The Journal of Immunology.
[34] R Hal Scofield,et al. Development of autoantibodies before the clinical onset of systemic lupus erythematosus. , 2003, The New England journal of medicine.
[35] G. Karypis,et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[36] Virginia Pascual,et al. Plasmacytoid dendritic cells induce plasma cell differentiation through type I interferon and interleukin 6. , 2003, Immunity.
[37] M. Walport,et al. The role of complement in the development of systemic lupus erythematosus. , 2004, Annual review of immunology.
[38] J. Metzger,et al. Toll‐like receptor 9 binds single‐stranded CpG‐DNA in a sequence‐ and pH‐dependent manner , 2004, European journal of immunology.
[39] L. Rönnblom,et al. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. , 2004, Arthritis and rheumatism.
[40] A. Zychlinsky,et al. Neutrophil Extracellular Traps Kill Bacteria , 2004, Science.
[41] D. Isenberg,et al. Compromised Function of Regulatory T Cells in Rheumatoid Arthritis and Reversal by Anti-TNFα Therapy , 2004, The Journal of experimental medicine.
[42] B. Monks,et al. TLR9 signals after translocating from the ER to CpG DNA in the lysosome , 2004, Nature Immunology.
[43] D. Golenbock,et al. Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9. , 2005, The Journal of clinical investigation.
[44] B. Beutler,et al. Type I interferons (alpha/beta) in immunity and autoimmunity. , 2005, Annual review of immunology.
[45] S. Datta,et al. A Defect in Deletion of Nucleosome-Specific Autoimmune T Cells in Lupus-Prone Thymus: Role of Thymic Dendritic Cells1 , 2005, The Journal of Immunology.
[46] Yong‐jun Liu,et al. IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors. , 2005, Annual review of immunology.
[47] J. Moreau,et al. Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus. , 2005, Arthritis and rheumatism.
[48] S. Akira,et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus , 2005, The Journal of experimental medicine.
[49] Hideo Negishi,et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses , 2005, Nature.
[50] B. Beutler,et al. TYPE I INTERFERONS (/) IN IMMUNITY AND AUTOIMMUNITY , 2005 .
[51] S. Akira,et al. Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8 , 2005, The Journal of experimental medicine.
[52] K. Honda,et al. Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction , 2005, Nature.
[53] G. Stark,et al. Complex modulation of cell type-specific signaling in response to type I interferons. , 2006, Immunity.
[54] V. Pascual,et al. Type I interferon in systemic lupus erythematosus and other autoimmune diseases. , 2006, Immunity.
[55] L. Pasquier,et al. Orphanet Journal of Rare Diseases , 2006 .
[56] S. Akira,et al. U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7. , 2006, Blood.
[57] A. Marshak‐Rothstein. Toll-like receptors in systemic autoimmune disease , 2006, Nature Reviews Immunology.
[58] J. Vilček. Fifty years of interferon research: aiming at a moving target. , 2006, Immunity.
[59] J. Harley,et al. Unraveling the genetics of systemic lupus erythematosus , 2006, Springer Seminars in Immunopathology.
[60] R. Lafyatis,et al. Antimalarial agents: closing the gate on Toll-like receptors? , 2006, Arthritis and rheumatism.
[61] P. Concannon,et al. Genetic Variation in PTPN22 Corresponds to Altered Function of T and B Lymphocytes1 , 2007, The Journal of Immunology.
[62] Wentian Li,et al. STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. , 2007, The New England journal of medicine.
[63] J. Lieberman,et al. Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 are associated with systemic lupus erythematosus , 2007, Nature Genetics.
[64] P. Hertzog,et al. The role of type I interferons in TLR responses , 2007, Immunology and cell biology.
[65] Volker Brinkmann,et al. Beneficial suicide: why neutrophils die to make NETs , 2007, Nature Reviews Microbiology.
[66] B. Beutler,et al. TLR-dependent and TLR-independent pathways of type I interferon induction in systemic autoimmunity , 2007, Nature Medicine.
[67] L. Audoly,et al. Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE , 2007, Nature Immunology.
[68] A. Krieg,et al. Toll‐like receptors 7, 8, and 9: linking innate immunity to autoimmunity , 2007, Immunological reviews.
[69] I. Mellman,et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide , 2007, Nature.
[70] Geoffrey Hom,et al. Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus , 2007, Proceedings of the National Academy of Sciences.
[71] V. Pascual,et al. The innate immune system in SLE: type I interferons and dendritic cells , 2008, Lupus.
[72] Wei Chen,et al. A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosus , 2008, Nature Genetics.
[73] R. Coffman,et al. Development of TLR inhibitors for the treatment of autoimmune diseases , 2008, Immunological reviews.
[74] T. Hudson,et al. Association of LY9 in UK and Canadian SLE families , 2008, Genes and Immunity.
[75] Geoffrey Hom,et al. Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. , 2008, The New England journal of medicine.
[76] F. Dammacco,et al. Glomerular accumulation of plasmacytoid dendritic cells in active lupus nephritis: role of interleukin-18. , 2008, Arthritis and rheumatism.
[77] Sandra D'Alfonso,et al. Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus , 2008, Nature Genetics.
[78] Marta E Alarcón-Riquelme,et al. Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci , 2008, Nature Genetics.
[79] M. Gilliet,et al. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases , 2008, Nature Reviews Immunology.
[80] T. Heidmann,et al. Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity , 2008, Cell.
[81] P. Kiener,et al. Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus. , 2009, Arthritis and rheumatism.
[82] G. Obermoser,et al. Recruitment of plasmacytoid dendritic cells in ultraviolet irradiation‐induced lupus erythematosus tumidus , 2009, The British journal of dermatology.
[83] L. Rönnblom,et al. C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis. , 2009, Arthritis and rheumatism.
[84] T. Habib,et al. Cutting Edge: The PTPN22 Allelic Variant Associated with Autoimmunity Impairs B Cell Signaling1 , 2009, The Journal of Immunology.
[85] Don L. Armstrong,et al. Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus , 2009, Proceedings of the National Academy of Sciences.
[86] C. Langefeld,et al. Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies , 2009, Nature Reviews Genetics.
[87] Gerald McGwin,et al. A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus , 2009, Nature Genetics.
[88] A. Krieg,et al. Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists. , 2009, Advanced drug delivery reviews.
[89] L. Rönnblom,et al. Type I interferon and lupus , 2009, Current opinion in rheumatology.
[90] J. Harley,et al. Recent insights into the genetic basis of systemic lupus erythematosus , 2009, Genes and Immunity.
[91] M. Gilliet,et al. Self-RNA–antimicrobial peptide complexes activate human dendritic cells through TLR7 and TLR8 , 2009, The Journal of experimental medicine.
[92] T. Behrens,et al. Review of recent genome‐wide association scans in lupus , 2009, Journal of internal medicine.
[93] D. Isenberg,et al. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients. , 2010, Immunity.
[94] A. Syvänen,et al. Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus. , 2010, Arthritis and rheumatism.
[95] C. Benoist,et al. Levees of immunological tolerance , 2010, Nature Immunology.