Low normal FMR1 genotype in older adult women: Psychological well-being and motor function.

[1]  Ming Li,et al.  Revisiting tandem repeats in psychiatric disorders from perspectives of genetics, physiology, and brain evolution , 2021, Molecular Psychiatry.

[2]  C. Coe,et al.  Stress and genetics influence hair cortisol in FMR1 premutation carrier mothers of children with fragile X syndrome , 2021, Psychoneuroendocrinology.

[3]  E. Lyon,et al.  Laboratory testing for fragile X, 2021 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG) , 2021, Genetics in Medicine.

[4]  C. Rorden,et al.  The Aging Brain Cohort (ABC) repository: The University of South Carolina’s multimodal lifespan database for studying the relationship between the brain, cognition, genetics and behavior in healthy aging , 2021 .

[5]  Xinyu Zhao,et al.  The molecular biology of FMRP: new insights into fragile X syndrome , 2021, Nature Reviews Neuroscience.

[6]  Amanda J. Fairchild,et al.  Response Inhibition Deficits in Women with the FMR1 Premutation are Associated with Age and Fall Risk , 2020, Brain and Cognition.

[7]  D. Loesch,et al.  Differential Progression of Motor Dysfunction Between Male and Female Fragile X Premutation Carriers Reveals Novel Aspects of Sex-Specific Neural Involvement , 2021, Frontiers in Molecular Biosciences.

[8]  H. Inada,et al.  Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis , 2020, Molecular Brain.

[9]  K. Bötzel,et al.  Loss of Fragile X Mental Retardation Protein (FMRP) precedes Lewy pathology in Parkinson's Disease , 2020 .

[10]  T. Vangberg,et al.  What does hand motor function tell us about our aging brain in association with WMH? , 2020, Aging Clinical and Experimental Research.

[11]  D. Hall,et al.  Prodromal Markers of Upper Limb Deficits in FMR1 Premutation Carriers and Quantitative Outcome Measures for Future Clinical Trials in Fragile X‐associated Tremor/Ataxia Syndrome , 2020, Movement disorders clinical practice.

[12]  M. Brilliant,et al.  FMR1 Low Zone CGG Repeats: Phenotypic Associations in the Context of Parenting Stress , 2020, Frontiers in Pediatrics.

[13]  D. Melzer,et al.  The genetics of human ageing , 2019, Nature Reviews Genetics.

[14]  Matthew W. Mosconi,et al.  Precision Sensorimotor Control in Aging FMR1 Gene Premutation Carriers , 2019, Front. Integr. Neurosci..

[15]  J. Greenberg,et al.  Positive Emotional Support in Premutation Carrier Mothers of Adolescents and Adults With Fragile X Syndrome: Gene by Environment Interactions. , 2019, American journal on intellectual and developmental disabilities.

[16]  R. Stewart,et al.  Data-driven phenotype discovery of FMR1 premutation carriers in a population-based sample , 2019, Science Advances.

[17]  Matthew W. Mosconi,et al.  Functional motor control deficits in older FMR1 premutation carriers , 2019, Experimental Brain Research.

[18]  Matthew W. Mosconi,et al.  Static and dynamic postural control deficits in aging fragile X mental retardation 1 (FMR1) gene premutation carriers , 2019, Journal of Neurodevelopmental Disorders.

[19]  D. Albertini,et al.  Reduced RNA expression of the FMR1 gene in women with low (CGGn<26) repeats , 2018, PloS one.

[20]  Jane E. Roberts,et al.  Curvilinear Association Between Language Disfluency and FMR1 CGG Repeat Size Across the Normal, Intermediate, and Premutation Range , 2018, Front. Genet..

[21]  I. Brum,et al.  FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve , 2018, Reproductive Biology and Endocrinology.

[22]  Q. Bui,et al.  FMR1 allele size distribution in 35,000 males and females: a comparison of developmental delay and general population cohorts , 2018, Genetics in Medicine.

[23]  M. Brilliant,et al.  Is Low FMR1 CGG Repeat Length in Males Correlated with Family History of BRCA-Associated Cancers? An Exploratory Analysis of Medical Records , 2017, Journal of Genetic Counseling.

[24]  Dalyir I. Pretto,et al.  Molecular biomarkers predictive of sertraline treatment response in young children with fragile X syndrome , 2017, Brain and Development.

[25]  J. Greenberg,et al.  FMR1 genotype interacts with parenting stress to shape health and functional abilities in older age , 2017, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[26]  S. Young,et al.  Distribution of the FMR1 gene in females by race/ethnicity: women with diminished ovarian reserve versus women with normal fertility (SWAN study). , 2015, Fertility and sterility.

[27]  P. Hagerman,et al.  Fragile X-associated tremor/ataxia syndrome — features, mechanisms and management , 2016, Nature Reviews Neurology.

[28]  M. Hill,et al.  Is FMR1 CGG repeat length a predictor of in vitro fertilization stimulation response or outcome? , 2016, Fertility and sterility.

[29]  Jane E. Roberts,et al.  Trajectory and Predictors of Depression and Anxiety Disorders in Mothers With the FMR1 Premutation , 2016, Biological Psychiatry.

[30]  Ewout J. N. Groen,et al.  Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways , 2016, Acta Neuropathologica.

[31]  J. Franasiak,et al.  FMR1 gene CGG repeat variation within the normal range is not predictive of ovarian response in IVF cycles. , 2016, Reproductive biomedicine online.

[32]  Jonathan P. Beauchamp,et al.  Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses , 2016, Nature Genetics.

[33]  A. Manichaikul,et al.  FMR1 CGG Repeats , 2016, Reproductive sciences.

[34]  A. Owen,et al.  Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity , 2015, PLoS genetics.

[35]  Karen V. Lomond,et al.  Detection of postural sway abnormalities by wireless inertial sensors in minimally disabled patients with multiple sclerosis: a case–control study , 2015, Journal of NeuroEngineering and Rehabilitation.

[36]  Espen Røysamb,et al.  The heritability of subjective well-being: review and meta-analysis , 2015 .

[37]  Youping Deng,et al.  Characterization and Early Detection of Balance Deficits in Fragile X Premutation Carriers With and Without Fragile X-Associated Tremor/Ataxia Syndrome (FXTAS) , 2015, The Cerebellum.

[38]  Hansen Wang.  Fragile X mental retardation protein: from autism to neurodegenerative disease , 2015, Front. Cell. Neurosci..

[39]  J. Bradshaw,et al.  Age and CGG-repeat length are associated with neuromotor impairments in at-risk females with the FMR1 premutation , 2014, Neurobiology of Aging.

[40]  J. Greenberg,et al.  Low-normal FMR1 CGG repeat length: phenotypic associations , 2014, Front. Genet..

[41]  M. Rogers,et al.  Pattern of age‐associated decline of static and dynamic balance in community‐dwelling older women , 2014, Geriatrics & gerontology international.

[42]  O. Rivero-Arias,et al.  Epidemiology of fragile X syndrome: A systematic review and meta‐analysis , 2014, American journal of medical genetics. Part A.

[43]  P. Chiarelli,et al.  Normative scores on the Berg Balance Scale decline after age 70 years in healthy community-dwelling people: a systematic review. , 2014, Journal of physiotherapy.

[44]  Andreas Ziegler,et al.  How to Include Chromosome X in Your Genome‐Wide Association Study , 2014, Genetic epidemiology.

[45]  E. Gennaro,et al.  A novel methylation PCR that offers standardized determination of FMR1 methylation and CGG repeat length without southern blot analysis. , 2014, The Journal of molecular diagnostics : JMD.

[46]  C. Peterson,et al.  Assessing psychological well-being: self-report instruments for the NIH Toolbox , 2014, Quality of Life Research.

[47]  J. Darnell,et al.  The translation of translational control by FMRP: therapeutic targets for FXS , 2013, Nature Neuroscience.

[48]  J. Mathers,et al.  Towards measurement of the Healthy Ageing Phenotype in lifestyle-based intervention studies. , 2013, Maturitas.

[49]  Jonathan Cohen,et al.  Cognitive-motor interference during postural control indicates at-risk cerebellar profiles in females with the FMR1 premutation , 2013, Behavioural Brain Research.

[50]  William Z Rymer,et al.  Motor assessment using the NIH Toolbox , 2013, Neurology.

[51]  Andrea Schneider,et al.  Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles , 2013, NeuroImage.

[52]  D. Nguyen,et al.  FMR1 CGG allele size and prevalence ascertained through newborn screening in the United States , 2012, Genome Medicine.

[53]  C. Singer,et al.  BRCA1/2 Mutations Appear Embryo-Lethal Unless Rescued by Low (CGG n<26) FMR1 Sub-Genotypes: Explanation for the “BRCA Paradox”? , 2012, PloS one.

[54]  J. Greenberg,et al.  Differential sensitivity to life stress in FMR1 premutation carrier mothers of children with fragile X syndrome. , 2012, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[55]  Small genomic rearrangements involving FMR1 support the importance of its gene dosage for normal neurocognitive function , 2012, neurogenetics.

[56]  J. Greenberg,et al.  Prevalence of CGG expansions of the FMR1 gene in a US population‐based sample , 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[57]  Q. Wang,et al.  Neurodegeneration-associated TDP-43 Interacts with Fragile X Mental Retardation Protein (FMRP)/Staufen (STAU1) and Regulates SIRT1 Expression in Neuronal Cells* , 2012, The Journal of Biological Chemistry.

[58]  E. Peprah.  Fragile X Syndrome: The FMR1 CGG Repeat Distribution Among World Populations , 2012, Annals of human genetics.

[59]  B. Zehnbauer,et al.  Molecular genetic testing for fragile X syndrome: laboratory performance on the College of American Pathologists proficiency surveys (2001–2009) , 2012, Genetics in Medicine.

[60]  Richard W. Bohannon,et al.  Assessing dexterity function: a comparison of two alternatives for the NIH Toolbox. , 2011, Journal of hand therapy : official journal of the American Society of Hand Therapists.

[61]  D. Licatalosi,et al.  FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism , 2011, Cell.

[62]  J. Neve.  Functional polymorphism (5-HTTLPR) in the serotonin transporter gene is associated with subjective well-being: evidence from a US nationally representative sample , 2011, Journal of Human Genetics.

[63]  D. Barad,et al.  Association of FMR1 Genotypes with In Vitro Fertilization (IVF) Outcomes Based on Ethnicity/Race , 2011, PloS one.

[64]  B. Ray,et al.  Autism, Alzheimer disease, and fragile X , 2011, Neurology.

[65]  Mark F Bear,et al.  Toward fulfilling the promise of molecular medicine in fragile X syndrome. , 2011, Annual review of medicine.

[66]  E. Sekinger,et al.  An information-rich CGG repeat primed PCR that detects the full range of fragile X expanded alleles and minimizes the need for southern blot analysis. , 2010, The Journal of molecular diagnostics : JMD.

[67]  J. Malter,et al.  Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid. , 2010, Current Alzheimer research.

[68]  D. Barad,et al.  Effects of race/ethnicity on triple CGG counts in the FMR1 gene in infertile women and egg donors. , 2010, Reproductive biomedicine online.

[69]  Tiffany R. Oliver,et al.  Examination of FMR1 transcript and protein levels among 74 premutation carriers , 2010, Journal of Human Genetics.

[70]  F. Huppert.  Psychological Well-being: Evidence Regarding its Causes and Consequences† , 2009 .

[71]  P. Harris,et al.  Research electronic data capture (REDCap) - A metadata-driven methodology and workflow process for providing translational research informatics support , 2009, J. Biomed. Informatics.

[72]  Jane E. Roberts,et al.  Mood and anxiety disorders in females with the FMR1 premutation , 2009, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[73]  H. Zoghbi,et al.  Failure of neuronal homeostasis results in common neuropsychiatric phenotypes , 2008, Nature.

[74]  C. Goetz,et al.  FMR1 CGG repeat length predicts motor dysfunction in premutation carriers , 2008, Neurology.

[75]  Jean F Wyman,et al.  Psychometric Properties of the Activities‐Specific Balance Confidence Scale and the Survey of Activities and Fear of Falling in Older Women , 2008, Journal of the American Geriatrics Society.

[76]  D. Hessl,et al.  Brief Report: Aggression and Stereotypic Behavior in Males with Fragile X Syndrome—Moderating Secondary Genes in a “Single Gene” Disorder , 2008, Journal of autism and developmental disorders.

[77]  Lexin Li,et al.  CGG repeat length correlates with age of onset of motor signs of the fragile X‐associated tremor/ataxia syndrome (FXTAS) , 2007, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[78]  Margaret L. Kern,et al.  Health benefits: Meta-analytically determining the impact of well-being on objective health outcomes , 2007 .

[79]  J. Malter,et al.  FMRP Mediates mGluR5-Dependent Translation of Amyloid Precursor Protein , 2007, PLoS biology.

[80]  Nancy D. Giles,et al.  Psychological well-being of mothers of youth with fragile X syndrome: syndrome specificity and within-syndrome variability. , 2006, Journal of intellectual disability research : JIDR.

[81]  P. Hagerman,et al.  The (CGG)n repeat element within the 5' untranslated region of the FMR1 message provides both positive and negative cis effects on in vivo translation of a downstream reporter. , 2003, Human molecular genetics.

[82]  William J Doyle,et al.  Emotional Style and Susceptibility to the Common Cold , 2003, Psychosomatic medicine.

[83]  W. Miller,et al.  Psychometric properties of the Activities-specific Balance Confidence Scale among individuals with a lower-limb amputation. , 2003, Archives of physical medicine and rehabilitation.

[84]  Michael Alexander,et al.  Age-Related Differences in Movement Representation , 2002, NeuroImage.

[85]  S. Warren,et al.  Reduced FMRP and increased FMR1 transcription is proportionally associated with CGG repeat number in intermediate-length and premutation carriers. , 2001, Human molecular genetics.

[86]  W. Friesen,et al.  PERSONALITY PROCESSES AND INDIVIDUAL DIFFERENCES Positive Emotions in Early Life and Longevity : Findings from the Nun Study , 2004 .

[87]  T. Godfrey,et al.  Elevated levels of FMR1 mRNA in carrier males: a new mechanism of involvement in the fragile-X syndrome. , 2000, American journal of human genetics.

[88]  R. Kirk.  Practical Significance: A Concept Whose Time Has Come , 1996 .

[89]  M A Hughes,et al.  The relationship of postural sway to sensorimotor function, functional performance, and disability in the elderly. , 1996, Archives of physical medicine and rehabilitation.

[90]  L. E. Powell,et al.  The Activities-specific Balance Confidence (ABC) Scale. , 1995, The journals of gerontology. Series A, Biological sciences and medical sciences.

[91]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .

[92]  E. Diener,et al.  Review of the Satisfaction with Life Scale , 1993 .

[93]  R. Larsen,et al.  The Satisfaction with Life Scale , 1985, Journal of personality assessment.

[94]  D. Cox,et al.  An Analysis of Transformations , 1964 .