LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer

[1]  Sangkyu Lee,et al.  LDHA Desuccinylase Sirtuin 5 as A Novel Cancer Metastatic Stimulator in Aggressive Prostate Cancer , 2022, Genom. Proteom. Bioinform..

[2]  U. Megwalu,et al.  Thyroid Cancer Incidence and Mortality Trends in the United States: 2000 - 2018. , 2022, Thyroid : official journal of the American Thyroid Association.

[3]  N. Du,et al.  STAT3/LINC00671 axis regulates papillary thyroid tumor growth and metastasis via LDHA-mediated glycolysis , 2021, Cell Death & Disease.

[4]  C. Gong,et al.  Characterizing dedifferentiation of thyroid cancer by integrated analysis , 2021, Science Advances.

[5]  Li Zhao,et al.  Nuclear scaffold protein p54nrb/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma , 2021, Oncogene.

[6]  B. Ahn,et al.  Molecular mechanisms of radioactive iodine refractoriness in differentiated thyroid cancer: Impaired sodium iodide symporter (NIS) expression owing to altered signaling pathway activity and intracellular localization of NIS , 2021, Theranostics.

[7]  Xi Wei,et al.  LDHA induces EMT gene transcription and regulates autophagy to promote the metastasis and tumorigenesis of papillary thyroid carcinoma , 2021, Cell Death & Disease.

[8]  Hong Zhang,et al.  Epigenetic Regulation of Papillary Thyroid Carcinoma by long non-coding RNAs. , 2021, Seminars in cancer biology.

[9]  W. Xue,et al.  SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis , 2021, Nature Communications.

[10]  L. Fournel,et al.  Metabolic Strategies for Inhibiting Cancer Development. , 2021, Advances in nutrition.

[11]  C. Romier,et al.  Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation , 2019, Nature Communications.

[12]  Jiancheng Hu,et al.  Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer , 2020, Journal of experimental & clinical cancer research : CR.

[13]  Junwei Huang,et al.  Up-regulated ANP32E promotes the thyroid carcinoma cell proliferation and migration via activating AKT/mTOR/HK2-mediated glycolysis. , 2020, Gene.

[14]  J. Manzo-Merino,et al.  Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches , 2019, Front. Oncol..

[15]  Yu-qin Pan,et al.  LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor immune cell microenvironment in colorectal cancer by regulating SATB2 , 2019, Molecular Cancer.

[16]  S. Kang,et al.  FDG PET/CT for the early prediction of RAI therapy response in patients with metastatic differentiated thyroid carcinoma , 2019, PloS one.

[17]  F. Su,et al.  Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells , 2019, Nature Cell Biology.

[18]  Yu-qin Pan,et al.  lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer , 2019, Journal of Hematology & Oncology.

[19]  Li Zhao,et al.  SIRT5‐mediated deacetylation of LDHB promotes autophagy and tumorigenesis in colorectal cancer , 2018, Molecular oncology.

[20]  Yu-qin Pan,et al.  The long noncoding RNA SNHG1 regulates colorectal cancer cell growth through interactions with EZH2 and miR-154-5p , 2018, Molecular Cancer.

[21]  E. Ruppin,et al.  Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival , 2018, The EMBO journal.

[22]  Jianjun Liu,et al.  Met is involved in TIGAR-regulated metastasis of non-small-cell lung cancer , 2018, Molecular Cancer.

[23]  Di Chen,et al.  The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma , 2018, Nature Communications.

[24]  A. Veronese,et al.  Non-coding RNAs in the reprogramming of glucose metabolism in cancer. , 2018, Cancer letters.

[25]  G. Brooks.  The Science and Translation of Lactate Shuttle Theory. , 2018, Cell metabolism.

[26]  Y. Li,et al.  Transcriptional Regulation of the Warburg Effect in Cancer by SIX1. , 2018, Cancer cell.

[27]  F. Slack,et al.  Non-coding RNA networks in cancer , 2017, Nature Reviews Cancer.

[28]  Joshua D. Rabinowitz,et al.  Glucose feeds the TCA cycle via circulating lactate , 2017, Nature.

[29]  S. Devesa,et al.  Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013 , 2017, JAMA.

[30]  F. Khuri,et al.  Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis , 2017, Oncogene.

[31]  S. Mandel,et al.  2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer. , 2009, Thyroid : official journal of the American Thyroid Association.

[32]  R. Taboła,et al.  Lactate dehydrogenase 5: an old friend and a new hope in the war on cancer. , 2015, Cancer letters.

[33]  Xuetao Cao,et al.  The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation , 2014, Science.

[34]  J. Geschwind,et al.  Tumor glycolysis as a target for cancer therapy: progress and prospects , 2013, Molecular Cancer.

[35]  Yingming Zhao,et al.  SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. , 2013, Molecular cell.

[36]  Y. Xiong,et al.  Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer. , 2013, Cancer cell.

[37]  D. Hanahan,et al.  Hallmarks of Cancer: The Next Generation , 2011, Cell.

[38]  B. Quistorff,et al.  High brain lactate is not caused by a shift in the lactate dehydrogenase A/B ratio , 2011, Proceedings of the National Academy of Sciences.

[39]  Christopher Korch,et al.  Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification. , 2008, The Journal of clinical endocrinology and metabolism.

[40]  Mithat Gonen,et al.  Real-time prognosis for metastatic thyroid carcinoma based on 2-[18F]fluoro-2-deoxy-D-glucose-positron emission tomography scanning. , 2006, The Journal of clinical endocrinology and metabolism.

[41]  E. Baudin,et al.  Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma: benefits and limits of radioiodine therapy. , 2006, The Journal of clinical endocrinology and metabolism.

[42]  S. Larson,et al.  Resistance of [18f]-fluorodeoxyglucose-avid metastatic thyroid cancer lesions to treatment with high-dose radioactive iodine. , 2001, Thyroid : official journal of the American Thyroid Association.