Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex
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Kris Gevaert | Joel Vandekerckhove | Alan Hall | I. Jordens | A. Hall | K. Gevaert | J. Vandekerckhove | S. Krugmann | Ingrid Jordens | Sonja Krugmann | Mariëtte Driessens | M. Driessens | Ingrid Jordens | A. Hall
[1] C. Monfries,et al. Cdc42hs Facilitates Cytoskeletal Reorganization and Neurite Outgrowth by Localizing the 58-Kd Insulin Receptor Substrate to Filamentous Actin , 2001, The Journal of cell biology.
[2] Elaine Fuchs,et al. Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion , 2000, Cell.
[3] J. Wehland,et al. Mena, a Relative of VASP and Drosophila Enabled, Is Implicated in the Control of Microfilament Dynamics , 1996, Cell.
[4] M. Olson,et al. Yeast two-hybrid system to detect protein-protein interactions with Rho GTPases. , 1995, Methods in Enzymology.
[5] U. Francke,et al. Wiskott–Aldrich Syndrome Protein, a Novel Effector for the GTPase CDC42Hs, Is Implicated in Actin Polymerization , 1996, Cell.
[6] J. Juang,et al. Phosphorylation of Enabled by the DrosophilaAbelson Tyrosine Kinase Regulates the In Vivo Function and Protein-Protein Interactions of Enabled , 1998, Molecular and Cellular Biology.
[7] M. Kirschner,et al. Mechanism of N-Wasp Activation by Cdc42 and Phosphatidylinositol 4,5-Bisphosphate , 2000, The Journal of cell biology.
[8] Yoshimi Takai,et al. Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP , 1998, Nature.
[9] J. Hartwig,et al. WIP regulates N-WASP-mediated actin polymerization and filopodium formation , 2001, Nature Cell Biology.
[10] Y. Nakamura,et al. Identification of BAIAP2 (BAI-associated protein 2), a novel human homologue of hamster IRSp53, whose SH3 domain interacts with the cytoplasmic domain of BAI1 , 1999, Cytogenetic and Genome Research.
[11] P. Cossart,et al. Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation , 1999, Current Biology.
[12] Gary G. Borisy,et al. Arp2/3 Complex and Actin Depolymerizing Factor/Cofilin in Dendritic Organization and Treadmilling of Actin Filament Array in Lamellipodia , 1999, The Journal of cell biology.
[13] D. Jay,et al. The clutch hypothesis revisited: ascribing the roles of actin-associated proteins in filopodial protrusion in the nerve growth cone. , 2000, Journal of neurobiology.
[14] L. Lim,et al. The Ras-related protein Cdc42Hs and bradykinin promote formation of peripheral actin microspikes and filopodia in Swiss 3T3 fibroblasts , 1995, Molecular and cellular biology.
[15] Michael K. Rosen,et al. Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein , 2000, Nature.
[16] R. Roth,et al. Characterization and Cloning of a 58/53-kDa Substrate of the Insulin Receptor Tyrosine Kinase (*) , 1996, The Journal of Biological Chemistry.
[17] Laura M. Machesky,et al. Scar1 and the related Wiskott–Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex , 1998, Current Biology.
[18] Lorene M Lanier,et al. Mena Is Required for Neurulation and Commissure Formation , 1999, Neuron.
[19] U. Walter,et al. The EVH2 Domain of the Vasodilator-stimulated Phosphoprotein Mediates Tetramerization, F-actin Binding, and Actin Bundle Formation* , 1999, The Journal of Biological Chemistry.
[20] Marie-France Carlier,et al. Role of Proteins of the Ena/VASP Family in Actin-based Motility of Listeria monocytogenes , 1999, The Journal of cell biology.
[21] C. Nobes,et al. Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia , 1995, Cell.
[22] J. Wehland,et al. A novel proline‐rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family , 1997, The EMBO journal.
[23] R. Jahn,et al. 16-BAC/SDS-PAGE: a two-dimensional gel electrophoresis system suitable for the separation of integral membrane proteins. , 1996, Analytical biochemistry.
[24] P. Grabham,et al. Recruitment of the Arp2/3 complex and Mena for the stimulation of actin polymerization in growth cones by nerve growth factor , 2000, Journal of neuroscience research.
[25] A. Hall,et al. Measurement of intrinsic nucleotide exchange and GTP hydrolysis rates. , 1995, Methods in enzymology.
[26] James E Bear,et al. Negative Regulation of Fibroblast Motility by Ena/VASP Proteins , 2000, Cell.
[27] M. Abbott,et al. The Insulin Receptor Tyrosine Kinase Substrate p58/53 and the Insulin Receptor Are Components of CNS Synapses , 1999, The Journal of Neuroscience.
[28] Wange Lu,et al. Structure of PAK1 in an Autoinhibited Conformation Reveals a Multistage Activation Switch , 2000, Cell.
[29] A. Hall,et al. A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases (*) , 1995, The Journal of Biological Chemistry.
[30] S. Zigmond. How Wasp Regulates Actin Polymerization , 2000, The Journal of cell biology.
[31] T. Takenawa,et al. IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling , 2000, Nature.
[32] Anne J. Ridley,et al. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.
[33] A. Hall,et al. Rho GTPases and their effector proteins. , 2000, The Biochemical journal.
[34] K. Gevaert,et al. A peptide concentration and purification method for protein characterization in the subpicomole range using matrix assisted laser desorption/ionization‐postsource decay (MALDI‐PSD) sequencing , 1998, Electrophoresis.
[35] K. Gevaert,et al. Peptides adsorbed on reverse‐phase chromatographic beads as targets for femtomole sequencing by post‐source decay matrix assisted laser desorption ionization‐reflectron time of flight mass spectrometry (MALDI‐RETOF‐MS) , 1997, Electrophoresis.
[36] R. Cerione,et al. Flipping the Switch Minireview The Structural Basis for Signaling through the CRIB Motif , 2000, Cell.
[37] M. Sudol,et al. The WW Domain of Neural Protein FE65 Interacts with Proline-rich Motifs in Mena, the Mammalian Homolog of DrosophilaEnabled* , 1997, The Journal of Biological Chemistry.
[38] F. Hoffmann,et al. Genetic suppression of mutations in the Drosophila abl proto-oncogene homolog. , 1990, Science.
[39] U. Walter,et al. A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin‐based cytoskeleton of mammalian cells. , 1995, The EMBO journal.
[40] K. Nagata,et al. Activation of G1 Progression, JNK Mitogen-activated Protein Kinase, and Actin Filament Assembly by the Exchange Factor FGD1* , 1998, The Journal of Biological Chemistry.
[41] J. Vandekerckhove,et al. cAMP-dependent Protein Kinase Phosphorylation of EVL, a Mena/VASP Relative, Regulates Its Interaction with Actin and SH3 Domains* , 2000, The Journal of Biological Chemistry.
[42] Anne J. Ridley,et al. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling , 1992, Cell.
[43] A. Hall,et al. Rho GTPases and the actin cytoskeleton. , 1998, Science.