A spatial scan statistic

The scan statistic is commonly used to test if a one dimensional point process is purely random, or if any clusters can be detected. Here it is simultaneously extended in three directions:(i) a spatial scan statistic for the detection of clusters in a multi-dimensional point process is proposed, (ii) the area of the scanning window is allowed to vary, and (iii) the baseline process may be any inhomogeneous Poisson process or Bernoulli process with intensity pro-portional to some known function. The main interest is in detecting clusters not explained by the baseline process. These methods are illustrated on an epidemiological data set, but there are other potential areas of application as well.

[1]  M. Dwass Modified Randomization Tests for Nonparametric Hypotheses , 1957 .

[2]  E G Knox,et al.  The Detection of Space‐Time Interactions , 1964 .

[3]  J. Naus Clustering of random points in two dimensions , 1965 .

[4]  J. Naus The Distribution of the Size of the Maximum Cluster of Points on a Line , 1965 .

[5]  Bernard Saperstein,et al.  The Generalized Birthday Problem , 1972 .

[6]  Joseph Naus Probabilities for a Generalized Birthday Problem , 1974 .

[7]  R. Davies Hypothesis testing when a nuisance parameter is present only under the alternative , 1977 .

[8]  M A Weinstock,et al.  A generalised scan statistic test for the detection of clusters. , 1981, International journal of epidemiology.

[9]  Multiple clusters on the line , 1983 .

[10]  A. Whittemore,et al.  A test to detect clusters of disease , 1987 .

[11]  N. Cressie,et al.  Spatial Modeling of Regional Variables , 1993 .

[12]  C R Weinberg,et al.  Testing for a pulse in seasonal event data. , 1989, Biometrics.

[13]  J. Cuzick,et al.  Spatial clustering for inhomogeneous populations , 1990 .

[14]  B. Turnbull,et al.  Monitoring for clusters of disease: application to leukemia incidence in upstate New York. , 1990, American journal of epidemiology.

[15]  C. Loader Large-deviation approximations to the distribution of scan statistics , 1991, Advances in Applied Probability.

[16]  P J Diggle,et al.  Second-order analysis of spatial clustering for inhomogeneous populations. , 1991, Biometrics.

[17]  S. Sahu,et al.  Effect of relative risk and cluster configuration on the power of the one-dimensional scan statistic. , 1993, Statistics in medicine.

[18]  S Wallenstein,et al.  Power of the scan statistic for detection of clustering. , 1993, Statistics in medicine.

[19]  Joseph Naus,et al.  Power of the scan statistic in detecting a changed segment in a Bernoulli sequence , 1994 .

[20]  M Kulldorff,et al.  Spatial disease clusters: detection and inference. , 1995, Statistics in medicine.

[21]  M. Kulldorff,et al.  Childhood leukaemia in Sweden: using GIS and a spatial scan statistic for cluster detection. , 1996, Statistics in medicine.