Butyrate inhibits IL-1β-induced inflammatory gene expression by suppression of NF-κB activity in pancreatic beta cells
暂无分享,去创建一个
[1] Xiao Wang,et al. Sodium butyrate potentiates insulin secretion from rat islets at the expense of compromised expression of β cell identity genes , 2022, Cell death & disease.
[2] M. Qiao,et al. Butyrate Protects Pancreatic Beta Cells from Cytokine-Induced Dysfunction , 2021, International journal of molecular sciences.
[3] Yulong Yin,et al. Butyrate in Energy Metabolism: There Is Still More to Learn , 2021, Trends in Endocrinology & Metabolism.
[4] M. Lorincz,et al. Transcription shapes genome-wide histone acetylation patterns , 2021, Nature Communications.
[5] E. Kostenis,et al. FFA2-, but not FFA3-agonists inhibit GSIS of human pseudoislets: a comparative study with mouse islets and rat INS-1E cells , 2020, Scientific Reports.
[6] O. Pedersen,et al. Gut microbiota in human metabolic health and disease , 2020, Nature Reviews Microbiology.
[7] Annika Lundqvist,et al. The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study. , 2020, Cell metabolism.
[8] J. Weitz,et al. Dysfunction of Persisting β Cells Is a Key Feature of Early Type 2 Diabetes Pathogenesis. , 2020, Cell reports.
[9] P. de Vos,et al. Acetate and Butyrate Improve β-cell Metabolism and Mitochondrial Respiration under Oxidative Stress , 2020, International journal of molecular sciences.
[10] N. Billestrup,et al. Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications , 2019, Molecular and Cellular Endocrinology.
[11] M. Gannon,et al. The Beta Cell in Type 2 Diabetes , 2019, Current Diabetes Reports.
[12] Wen-Jeng Wu,et al. Epigenetic regulation of COX-2 expression by DNA hypomethylation via NF-κB activation in ketamine-induced ulcerative cystitis , 2019, International journal of molecular medicine.
[13] S. Han,et al. Short-chain Fatty Acids Inhibit Staphylococcal Lipoprotein-induced Nitric Oxide Production in Murine Macrophages , 2019, Immune network.
[14] Jingyuan Fu,et al. Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases , 2019, Nature Genetics.
[15] R. Gómez,et al. Butyrate Modulates Inflammation in Chondrocytes via GPR43 Receptor , 2018, Cellular Physiology and Biochemistry.
[16] Jing Chen,et al. Sodium butyrate mitigates type 2 diabetes by inhibiting PERK-CHOP pathway of endoplasmic reticulum stress. , 2018, Environmental toxicology and pharmacology.
[17] Chenlin Gao,et al. Sodium butyrate supplementation ameliorates diabetic inflammation in db/db mice. , 2018, The Journal of endocrinology.
[18] Matthew V. Holt,et al. Early butyrate induced acetylation of histone H4 is proteoform specific and linked to methylation state , 2018, Epigenetics.
[19] T. R. Licht,et al. Aberrant intestinal microbiota in individuals with prediabetes , 2018, Diabetologia.
[20] B. Wagner,et al. Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes , 2017, The Journal of Biological Chemistry.
[21] M. Donath,et al. The Role of Inflammation in β-cell Dedifferentiation , 2017, Scientific Reports.
[22] T. Sparer,et al. Pancreatic islet inflammation: an emerging role for chemokines. , 2017, Journal of molecular endocrinology.
[23] M. Zwinderman,et al. Histone deacetylase 3 (HDAC 3) as emerging drug target in NF-κB-mediated inflammation. , 2016, Current opinion in chemical biology.
[24] T. Umehara,et al. Histone H4 lysine 20 acetylation is associated with gene repression in human cells , 2016, Scientific Reports.
[25] Danhong Lu,et al. IL-1β reciprocally regulates chemokine and insulin secretion in pancreatic β-cells via NF-κB. , 2015, American journal of physiology. Endocrinology and metabolism.
[26] G. Jena,et al. Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat. , 2014, Chemico-biological interactions.
[27] S. Ghosh,et al. Regulation of the NF-κB-Mediated Transcription of Inflammatory Genes , 2014, Front. Immunol..
[28] Danhong Lu,et al. NF-κB and STAT1 control CXCL1 and CXCL2 gene transcription. , 2014, American journal of physiology. Endocrinology and metabolism.
[29] C. Workman,et al. Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection , 2014, Proceedings of the National Academy of Sciences.
[30] D. Hallinger,et al. Association of proinflammatory cytokines and islet resident leucocytes with islet dysfunction in type 2 diabetes , 2014, Diabetologia.
[31] M. Kleerebezem,et al. Modulation of the microbial fermentation in the gut by fermentable carbohydrates , 2013 .
[32] Danhong Lu,et al. Regulation of iNOS gene transcription by IL-1β and IFN-γ requires a coactivator exchange mechanism. , 2013, Molecular endocrinology.
[33] Ming-qing Li,et al. Butyrate alleviates metabolic impairments and protects pancreatic β cell function in pregnant mice with obesity. , 2013, International journal of clinical and experimental pathology.
[34] Fredrik H. Karlsson,et al. Gut metagenome in European women with normal, impaired and diabetic glucose control , 2013, Nature.
[35] M. Schmitz,et al. The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB , 2012, Nucleic acids research.
[36] I. Lundquist,et al. Pancreatic β‐cell dysfunction, expression of iNOS and the effect of phosphodiesterase inhibitors in human pancreatic islets of type 2 diabetes , 2012, Diabetes, obesity & metabolism.
[37] Qiang Feng,et al. A metagenome-wide association study of gut microbiota in type 2 diabetes , 2012, Nature.
[38] N. Morgan,et al. Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children , 2012, Diabetologia.
[39] Chunliu Yang,et al. Short-Chain Fatty Acids Suppress Lipopolysaccharide-Induced Production of Nitric Oxide and Proinflammatory Cytokines Through Inhibition of NF-κB Pathway in RAW264.7 Cells , 2012, Inflammation.
[40] S. Shoelson,et al. Type 2 diabetes as an inflammatory disease , 2011, Nature Reviews Immunology.
[41] P. Halban,et al. Cytokine production by islets in health and diabetes: cellular origin, regulation and function , 2010, Trends in Endocrinology & Metabolism.
[42] H. Ellingsgaard,et al. Islet inflammation impairs the pancreatic beta-cell in type 2 diabetes. , 2009, Physiology.
[43] P. Woster,et al. A novel histone deacetylase inhibitor prevents IL‐1β induced metabolic dysfunction in pancreatic β‐cells , 2009, Journal of cellular and molecular medicine.
[44] N. Morgan,et al. Islet-associated macrophages in type 2 diabetes , 2009, Diabetologia.
[45] W. Cefalu,et al. Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice , 2009, Diabetes.
[46] H. Afif,et al. Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E2 production in human chondrocytes. , 2008, Osteoarthritis and cartilage.
[47] A. Burny,et al. A pervasive role of histone acetyltransferases and deacetylases in an NF-kappaB-signaling code. , 2008, Trends in biochemical sciences.
[48] R. Mahato,et al. iNOS gene silencing prevents inflammatory cytokine-induced beta-cell apoptosis. , 2008, Molecular pharmaceutics.
[49] M. V. Suresh,et al. Regulatory roles for histone deacetylation in IL-1β-induced nitric oxide release in pancreatic β-cells , 2007, Journal of cellular and molecular medicine.
[50] H. Ellingsgaard,et al. Increased Number of Islet-Associated Macrophages in Type 2 Diabetes , 2007, Diabetes.
[51] Allan Vaag,et al. Interleukin-1-receptor antagonist in type 2 diabetes mellitus. , 2007, The New England journal of medicine.
[52] E. Seidman,et al. Dual effect of butyrate on IL-1beta--mediated intestinal epithelial cell inflammatory response. , 2007, DNA and cell biology.
[53] N. Sang,et al. Histone deacetylase inhibitors synergize p300 autoacetylation that regulates its transactivation activity and complex formation. , 2007, Cancer research.
[54] Hee-Sun Kim,et al. Anti-inflammatory effects of short chain fatty acids in IFN-γ-stimulated RAW 264.7 murine macrophage cells : Involvement of NF-κB and ERK signaling pathways , 2007 .
[55] S. G. Rønn,et al. Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells , 2007, Diabetologia.
[56] Zhi-yuan Yu,et al. Targeted histone H4 acetylation via phosphoinositide 3-kinase- and p70s6-kinase-dependent pathways inhibits iNOS induction in mesangial cells. , 2006, American journal of physiology. Renal physiology.
[57] D. Eizirik,et al. Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor κB-mediated gene expression in insulin-producing INS-1E cells , 2005, Diabetologia.
[58] R. Place,et al. HDAC inhibition prevents NF-κB activation by suppressing proteasome activity: Down-regulation of proteasome subunit expression stabilizes IκBα , 2005 .
[59] A. Pautz,et al. Regulation of the expression of inducible nitric oxide synthase. , 2004, European journal of pharmacology.
[60] C. Van Lint,et al. Regulation at multiple levels of NF-kappaB-mediated transactivation by protein acetylation. , 2004, Biochemical pharmacology.
[61] S. Kyrylenko,et al. Regulation of microglial inflammatory response by sodium butyrate and short‐chain fatty acids , 2004, British journal of pharmacology.
[62] A. Burny,et al. Potentiation of Tumor Necrosis Factor-Induced NF-κB Activation by Deacetylase Inhibitors Is Associated with a Delayed Cytoplasmic Reappearance of IκBα , 2003, Molecular and Cellular Biology.
[63] T. Menzel,et al. Butyrate Inhibits Interleukin-1-Mediated Nuclear Factor-Kappa B Activation in Human Epithelial Cells , 2001, Digestive Diseases and Sciences.
[64] Mogens Kruhøffer,et al. Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells. , 2003, Diabetes.
[65] J. Davie. Inhibition of histone deacetylase activity by butyrate. , 2003, The Journal of nutrition.
[66] Joachim Spranger,et al. Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. , 2003, Diabetes.
[67] C. Sardet,et al. Post-activation Turn-off of NF-κB-dependent Transcription Is Regulated by Acetylation of p65* , 2003, The Journal of Biological Chemistry.
[68] W. Greene,et al. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF‐κB , 2002, The EMBO journal.
[69] Wenzheng Zhang,et al. Histone deacetylases augment cytokine induction of the iNOS gene. , 2002, Journal of the American Society of Nephrology : JASN.
[70] S. Ghosh,et al. The Phosphorylation Status of Nuclear NF-ΚB Determines Its Association with CBP/p300 or HDAC-1 , 2002 .
[71] P. Becker,et al. Histone acetylation: a switch between repressive and permissive chromatin , 2002, EMBO reports.
[72] S. Saccani,et al. p38-dependent marking of inflammatory genes for increased NF-κB recruitment , 2002, Nature Immunology.
[73] M. M. Mu,et al. The inhibitory action of quercetin on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells. , 2001 .
[74] L. Yin,et al. Butyrate Suppression of Colonocyte NF-κB Activation and Cellular Proteasome Activity* , 2001, The Journal of Biological Chemistry.
[75] Eric Verdin,et al. Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation , 2001, Science.
[76] S. Saccani,et al. Two Waves of Nuclear Factor κb Recruitment to Target Promoters , 2001, The Journal of experimental medicine.
[77] M. Tyers,et al. Duration of Nuclear NF-kB Action Regulated by Reversible Acetylation , 2001 .
[78] J. Galmiche,et al. Butyrate inhibits inflammatory responses through NFkappaB inhibition: implications for Crohn's disease. , 2000, Gut.
[79] G. Spinas. The Dual Role of Nitric Oxide in Islet β-Cells , 1999 .
[80] D. Eizirik,et al. Regulation by cytokines of the inducible nitric oxide synthase promoter in insulin-producing cells , 1998, Diabetologia.
[81] M. Su,et al. Interleukin-1β-induced Rat Pancreatic Islet Nitric Oxide Synthesis Requires Both the p38 and Extracellular Signal-regulated Kinase 1/2 Mitogen-activated Protein Kinases* , 1998, The Journal of Biological Chemistry.
[82] G. Panagiotidis,et al. Interaction of the islet nitric oxide system with L‐arginine‐induced secretion of insulin and glucagon in mice , 1996, British journal of pharmacology.
[83] M. Mcdaniel,et al. Interleukin-1 beta-induced nitric oxide synthase expression by rat pancreatic beta-cells: evidence for the involvement of nuclear factor kappa B in the signaling mechanism. , 1995, Endocrinology.
[84] D. Eizirik,et al. Studies on the molecular regulation of the inducible form of nitric oxide synthase (iNOS) in insulin-producing cells , 1994, Molecular and Cellular Endocrinology.
[85] M. Mcdaniel,et al. Reversibility of interleukin-1 beta-induced islet destruction and dysfunction by the inhibition of nitric oxide synthase. , 1994, The Biochemical journal.
[86] N. Welsh,et al. Cytokines suppress human islet function irrespective of their effects on nitric oxide generation. , 1994, The Journal of clinical investigation.
[87] M. Mcdaniel,et al. Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[88] M. Mcdaniel,et al. Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide. , 1992, The Journal of clinical investigation.
[89] M. Mcdaniel,et al. Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion. , 1991, The Journal of biological chemistry.
[90] I. Green,et al. Inhibition of insulin secretion by interleukin‐1β and tumour necrosis factor‐α via an L‐arginine‐dependent nitric oxide generating mechanism , 1990 .
[91] Norma Banas,et al. Virtual Reality Visualization of 3-D Electromagnetic Fields , 2000 .