A population study on changes in wave aberrations with accommodation.

Wave aberrations were measured with a Shack-Hartmann wavefront sensor (SHWS) in the right eye of a large young adult population when accommodative demands of 0, 3, and 6 D were presented to the tested eye through a Badal system. Three SHWS images were recorded at each accommodative demand and wave aberrations were computed over a 5-mm pupil (through 6th order Zernike polynomials). The accommodative response was calculated from the Zernike defocus over the central 3-mm diameter zone. Among all individual Zernike terms, spherical aberration showed the greatest change with accommodation. The change of spherical aberration was always negative, and was proportional to the change in accommodative response. Coma and astigmatism also changed with accommodation, but the direction of the change was variable. Despite the large inter-subject variability, the population average of the root mean square for all aberrations (excluding defocus) remained constant for accommodative levels up to 3.0 D. Even though aberrations change with accommodation, the magnitude of the aberration change remains less than the magnitude of the uncorrected aberrations, even at high accommodative levels. Therefore, a typical eye will benefit over the entire accommodative range (0-6 D) if aberrations are corrected for distance viewing.

[1]  L. Garner,et al.  Changes in ocular dimensions and refraction with accommodation. , 1997, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[2]  G L Mitchell,et al.  Accommodation and induced with-the-rule astigmatism in emmetropes. , 2001, Optometry and vision science : official publication of the American Academy of Optometry.

[3]  Hiroshi Uozato,et al.  Accommodation Causes With-the-Rule Astigmatism in Emmetropes , 2000, Optometry and vision science : official publication of the American Academy of Optometry.

[4]  A. Bradley,et al.  Statistical variation of aberration structure and image quality in a normal population of healthy eyes. , 2002, Journal of the Optical Society of America. A, Optics, image science, and vision.

[5]  A. Bradley,et al.  Accuracy and precision of objective refraction from wavefront aberrations. , 2004, Journal of vision.

[6]  Arthur Bradley,et al.  A statistical model of the aberration structure of normal, well‐corrected eyes , 2002, Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians.

[7]  D. R. Iskander,et al.  Corneal Topography and Accommodation , 2003, Cornea.

[8]  Norberto López-Gil,et al.  Ocular wave-front aberration statistics in a normal young population , 2002, Vision Research.

[9]  Takashi Fujikado,et al.  Changes of ocular aberration with accommodation. , 2002, American journal of ophthalmology.

[10]  R. Held,et al.  Change in corneal shape and corneal wave-front aberrations with accommodation. , 2003, Journal of vision.

[11]  Larry N Thibos,et al.  Metrics of optical quality derived from wave aberrations predict visual performance. , 2004, Journal of vision.

[12]  Jane F. Koretz,et al.  Analysis of human crystalline lens curvature as a function of accommodative state and age , 1984, Vision Research.

[13]  Tatsuo Yamaguchi,et al.  Changes in corneal curvature in accommodation , 2003, Journal of cataract and refractive surgery.

[14]  Jenkins Tc,et al.  ABERRATIONS OF THE EYE AND THEIR EFFECTS ON VISION: 1. SPHERICAL ABERRATION. , 1963 .

[15]  Leon N. McLin,et al.  Changing size (looming) as a stimulus to accommodation and vergence , 1988, Vision Research.

[16]  Geunyoung Yoon,et al.  How Far Can We Extend the Limits of Human Vision ? , 2003 .

[17]  M Millodot,et al.  VARIATION OF ASTIGMATISM WITH ACCOMMODATION AND ITS RELATIONSHIP WITH DARK FOCUS , 1985, Ophthalmic & physiological optics.

[18]  C. A. Cook,et al.  Aging of the human lens: changes in lens shape upon accommodation and with accommodative loss. , 2002, Journal of the Optical Society of America. A, Optics, image science, and vision.

[19]  D. Williams,et al.  Monochromatic aberrations of the human eye in a large population. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[20]  David A. Atchison,et al.  Measurement of monochromatic ocular aberrations of human eyes as a function of accommodation by the howland aberroscope technique , 1995, Vision Research.

[21]  Pablo Artal,et al.  Are optical aberrations during accommodation a significant problem for refractive surgery? , 2002, Journal of refractive surgery.

[22]  S A Burns,et al.  Measurement of the wave-front aberration of the eye by a fast psychophysical procedure. , 1998, Journal of the Optical Society of America. A, Optics, image science, and vision.

[23]  Adrian Glasser,et al.  Wave aberrations of the isolated crystalline lens. , 2004, Journal of vision.

[24]  N. Brown,et al.  The change in shape and internal form of the lens of the eye on accommodation. , 1973, Experimental eye research.

[25]  P. Artal,et al.  Compensation of corneal aberrations by the internal optics in the human eye. , 2001, Journal of vision.

[26]  J. Schwiegerling,et al.  Customized corneal ablation and super vision. , 2000, Journal of refractive surgery.

[27]  A. Guirao,et al.  A Method to Predict Refractive Errors from Wave Aberration Data , 2003, Optometry and vision science : official publication of the American Academy of Optometry.

[28]  A. S. Vilupuru,et al.  Spatially variant changes in lens power during ocular accommodation in a rhesus monkey eye. , 2004, Journal of vision.

[29]  T. Jenkins,et al.  ABERRATIONS OF THE EYE AND THEIR EFFECTS ON VISION: 1. SPHERICAL ABERRATION. , 1963, The British journal of physiological optics.

[30]  George Smith,et al.  The spherical aberration of the crystalline lens of the human eye , 2001, Vision Research.

[31]  Richard Held,et al.  Wave-front aberrations in the anterior corneal surface and the whole eye. , 2003, Journal of the Optical Society of America. A, Optics, image science, and vision.

[32]  L. Thibos,et al.  Standards for reporting the optical aberrations of eyes. , 2002, Journal of refractive surgery.

[33]  E. Sarver,et al.  Interaction between aberrations to improve or reduce visual performance , 2003, Journal of cataract and refractive surgery.

[34]  S. Burns,et al.  Monochromatic aberrations in the accommodated human eye , 2000, Vision Research.

[35]  K P Thompson,et al.  Measurement of ocular local wavefront distortion with a spatially resolved refractometer. , 1992, Applied optics.

[36]  H. Howland,et al.  Computing high order wave aberration coefficients from variations of best focus for small artificial pupils , 1989, Vision Research.

[37]  F Berny.  [Study of the formation of retinal images and determination of the spherical aberration of the human eye]. , 1969, Vision research.

[38]  G. van den Brink,et al.  Measurements of the geometrical aberrations of the eye , 1962 .

[39]  R A Applegate,et al.  Optics of aberroscopy and super vision , 2001, Journal of cataract and refractive surgery.

[40]  A. Ivanoff,et al.  About the spherical aberration of the eye. , 1956, Journal of the Optical Society of America.

[41]  F. Berny,et al.  Contribution of the crystalline lens to the spherical aberration of the eye. , 1973, Journal of the Optical Society of America.

[42]  K Ukai,et al.  Changes in Ocular Astigmatism Over the Whole Range of Accommodation , 1991, Optometry and vision science : official publication of the American Academy of Optometry.

[43]  S A Burns,et al.  Age-related changes in monochromatic wave aberrations of the human eye. , 2001, Investigative ophthalmology & visual science.

[44]  M. Campbell,et al.  Presbyopia and the optical changes in the human crystalline lens with age , 1998, Vision Research.

[45]  H. Kasprzak,et al.  Corneal shape change during accommodation , 2001, Eye.

[46]  G Smith,et al.  Changes in Equivalent and Gradient Refractive Index of the Crystalline Lens with Accommodation , 1997, Optometry and vision science : official publication of the American Academy of Optometry.

[47]  Junzhong Liang,et al.  Aberrations and retinal image quality of the normal human eye. , 1997, Journal of the Optical Society of America. A, Optics, image science, and vision.

[48]  W. Bobier,et al.  Effects of Topical Anesthetics on Phenylephrine‐lnduced Mydriasis , 1977, American journal of optometry and physiological optics.