The Role of Calcium in Insulin Action - V. Importance of Cyclic Guanosine 3':5' Monophosphate and Calcium Ions in Insulin Stimulation of Lipoprotein Lipase Activity and Protein Synthesis in Adipose Tissue

Summary The effects of insulin on cyclic 3':5' guanosine monophos phate (c-GMP), 3H leucine incorporation into total fat cell protein and lipoprotein lipase activity have been studied in rat adipose tissue in vitro. The influence of changes in cal cium concentrations on these processes has also been ex amined.

[1]  P. Nilsson-ehle,et al.  Regulation of lipoprotein lipase. Induction by insulin. , 1976, Biochimica et biophysica acta.

[2]  G. Barritt,et al.  Administration of insulin to rats induces cycloheximide-sensitive changes in the calcium-ion-transport system of mitochondria isolated subsequently from liver. , 1975, Biochemical Society transactions.

[3]  B. Tulloch,et al.  The Role of Calcium in Insulin Action , 1975 .

[4]  C. Hollenberg,et al.  Regulation, by insulin, of lipoprotein lipase and phosphodiesterase activities in rat adipose tissue. , 1975, Israel journal of medical sciences.

[5]  B. Tulloch,et al.  MODE OF INSULIN ACTION , 1975, The Lancet.

[6]  D. Robinson,et al.  Studies on the assay of clearing factor lipase (lipoprotein lipase) , 1974 .

[7]  R. di Lauro,et al.  Stimulation of polypeptide synthesis by cyclic 3'-5'-guanosine monophosphate. , 1973, Archives of biochemistry and biophysics.

[8]  P. Cuatrecasas,et al.  Guanosine 3':5'-cyclic monophosphate and the action of insulin and acetylcholine. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[9]  A. Caswell,et al.  Kinetics of transport of divalent cations across sarcoplasmic reticulum vesicles induced by ionophores. , 1972, Biochemical and biophysical research communications.

[10]  P. Belfrage,et al.  Simple liquid-liquid partition system for isolation of labeled oleic acid from mixtures with glycerides. , 1969, Journal of lipid research.

[11]  R. Butcher,et al.  Effect of insulin on adenosine 3',5'-monophosphate in the rat epididymal fat pad. , 1966, The Journal of biological chemistry.

[12]  J. Fain,et al.  Cyclic guanosine 3':5'-monophosphate and the regulation of lipolysis in rat fat cells. , 1976, Journal of cyclic nucleotide research.

[13]  P. de Nayer.  Effect of cyclic 3'-5' GMP on in vitro protein synthesis. , 1973, Biochimie.