An Antibiotic from Penicillium sp. Covering the Cocoon of the Leaf-rolling Moth, Dactylioglypha tonica

An antibiotic-producing Penicillium sp. strain was isolated from cocoons of the leaf-rolling moth, Dactylioglypha tonica. An antibacterial compound was isolated from the cultured broth, and the chemical structure of the principle was determined by spectroscopic data to be a derivative of isocoumarincarboxylate.