Bioresponsive poly(amidoamine)s designed for intracellular protein delivery.

[1]  A. Kim,et al.  Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[2]  G. Miserocchi,et al.  A biophysical model of intracellular distribution and perinuclear accumulation of particulate matter. , 2011, Biophysical chemistry.

[3]  J. Engbersen,et al.  Functionalized linear poly(amidoamine)s are efficient vectors for intracellular protein delivery. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[4]  C. Mirkin,et al.  Cellular response of polyvalent oligonucleotide-gold nanoparticle conjugates. , 2010, ACS nano.

[5]  K. Kataoka,et al.  pDNA/poly(L-lysine) Polyplexes Functionalized with a pH-Sensitive Charge-Conversional Poly(aspartamide) Derivative for Controlled Gene Delivery to Human Umbilical Vein Endothelial Cells. , 2010, Macromolecular rapid communications.

[6]  Chad A. Mirkin,et al.  Gold nanoparticles for biology and medicine. , 2010, Angewandte Chemie.

[7]  N. Nishiyama,et al.  Efficient delivery of bioactive antibodies into the cytoplasm of living cells by charge-conversional polyion complex micelles. , 2010, Angewandte Chemie.

[8]  N. Nishiyama,et al.  Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm. , 2009, Angewandte Chemie.

[9]  R. Duncan,et al.  Poly(amidoamine) conjugates containing doxorubicin bound via an acid-sensitive linker. , 2009, Macromolecular bioscience.

[10]  J. Engbersen,et al.  The role of the disulfide group in disulfide-based polymeric gene carriers , 2009 .

[11]  Chad A. Mirkin,et al.  Gene regulation with polyvalent siRNA-nanoparticle conjugates. , 2009, Journal of the American Chemical Society.

[12]  J. Feijen,et al.  Novel poly(amido amine)s with bioreducible disulfide linkages in their diamino-units: structure effects and in vitro gene transfer properties. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[13]  T. Park,et al.  Enhanced intracellular delivery of quantum dot and adenovirus nanoparticles triggered by acidic pH via surface charge reversal. , 2008, Bioconjugate chemistry.

[14]  J. Feijen,et al.  Poly(amido amine)s as Gene Delivery Vectors: Effects of Quaternary Nicotinamide Moieties in the Side Chains , 2008, ChemMedChem.

[15]  J. Feijen,et al.  Bioreducible poly(amido amine)s with oligoamine side chains: synthesis, characterization, and structural effects on gene delivery. , 2008, Journal of controlled release : official journal of the Controlled Release Society.

[16]  J. Feijen,et al.  Random and block copolymers of bioreducible poly(amido amine)s with high- and low-basicity amino groups: study of DNA condensation and buffer capacity on gene transfection. , 2007, Journal of controlled release : official journal of the Controlled Release Society.

[17]  Kazunori Kataoka,et al.  A protein nanocarrier from charge-conversion polymer in response to endosomal pH. , 2007, Journal of the American Chemical Society.

[18]  J. Feijen,et al.  Linear poly(amido amine)s with secondary and tertiary amino groups and variable amounts of disulfide linkages: synthesis and in vitro gene transfer properties. , 2006, Journal of controlled release : official journal of the Controlled Release Society.

[19]  B. Ranjbar,et al.  Stepwise modification of lysine residues of glucose oxidase with citraconic anhydride. , 2006, International journal of biological macromolecules.

[20]  Chad A. Mirkin,et al.  Oligonucleotide-Modified Gold Nanoparticles for Intracellular Gene Regulation , 2006, Science.

[21]  K. Kataoka,et al.  pH-responsive three-layered PEGylated polyplex micelle based on a lactosylated ABC triblock copolymer as a targetable and endosome-disruptive nonviral gene vector. , 2006, Bioconjugate chemistry.

[22]  R. Cavalli,et al.  Synthesis, physicochemical properties, and preliminary biological characterizations of a novel amphoteric agmatine-based poly(amidoamine) with RGD-like repeating units. , 2006, Biomacromolecules.

[23]  A. Bernkop‐Schnürch Thiomers: a new generation of mucoadhesive polymers. , 2005, Advanced drug delivery reviews.

[24]  R. Duncan,et al.  Synthesis and preliminary evaluation of poly(amidoamine)-melittin conjugates as endosomolytic polymers and/or potential anticancer therapeutics. , 2005, International journal of pharmaceutics.

[25]  K. Khajeh,et al.  Chemical modification of lysine residues in Bacillus licheniformis alpha-amylase: conversion of an endo- to an exo-type enzyme. , 2004, Journal of biochemistry and molecular biology.

[26]  P. Ferruti,et al.  Perspectives on: Recent Advances in Poly(Amidoamine)s Chemistry , 2004 .

[27]  Atsushi Harada,et al.  Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: polymeric micelles that are responsive to intracellular pH change. , 2003, Angewandte Chemie.

[28]  C James Kirkpatrick,et al.  In vitro expression of the endothelial phenotype: comparative study of primary isolated cells and cell lines, including the novel cell line HPMEC-ST1.6R. , 2002, Microvascular research.

[29]  Robert Gurny,et al.  Poly(ortho esters): synthesis, characterization, properties and uses. , 2002, Advanced drug delivery reviews.

[30]  N. Murthy,et al.  A novel strategy for encapsulation and release of proteins: hydrogels and microgels with acid-labile acetal cross-linkers. , 2002, Journal of the American Chemical Society.

[31]  R. Duncan,et al.  Poly(amido‐amine)s: Biomedical Applications , 2002 .

[32]  V. Labhasetwar,et al.  Characterization of nanoparticle uptake by endothelial cells. , 2002, International journal of pharmaceutics.

[33]  R. Duncan,et al.  Poly(amidoamine)-mediated intracytoplasmic delivery of ricin A-chain and gelonin. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[34]  R. Duncan,et al.  Poly(amidoamine)s as potential nonviral vectors: ability to form interpolyelectrolyte complexes and to mediate transfection in vitro. , 2001, Biomacromolecules.

[35]  H. Naderi-manesh,et al.  Chemical modification of lysine residues in Bacillus α-amylases: effect on activity and stability , 2001 .

[36]  Eichman,et al.  The use of PAMAM dendrimers in the efficient transfer of genetic material into cells. , 2000, Pharmaceutical science & technology today.

[37]  D. Scherman,et al.  A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[38]  L. Sartore,et al.  Recent results on functional polymers and macromonomers of interest as biomaterials or for biomaterial modification. , 1994, Biomaterials.

[39]  K. M. Fazili,et al.  Chemical modification of buried lysine residues of bovine serum albumin and its influence on protein conformation and bilirubin binding. , 1992, Biochimica et biophysica acta.

[40]  E. Feener,et al.  Cleavage of disulfide bonds in endocytosed macromolecules. A processing not associated with lysosomes or endosomes. , 1990, The Journal of biological chemistry.

[41]  C H Wu,et al.  Receptor-mediated in vitro gene transformation by a soluble DNA carrier system. , 1987, The Journal of biological chemistry.

[42]  J. Bindels,et al.  The reaction of citraconic anhydride with bovine alpha-crystallin lysine residues. Surface probing and dissociation-reassociation studies. , 1985, Biochimica et biophysica acta.

[43]  J. Kinsella,et al.  Ready separation of proteins from nucleoprotein complexes by reversible modification of lysine residues. , 1980, The Biochemical journal.

[44]  Sidney Udenfriend,et al.  Fluorescamine: A Reagent for Assay of Amino Acids, Peptides, Proteins, and Primary Amines in the Picomole Range , 1972, Science.

[45]  J. Engbersen,et al.  Bioreducible poly(amidoamine)s as carriers for intracellular protein delivery to intestinal cells. , 2012, Biomaterials.

[46]  J. Feijen,et al.  Novel bioreducible poly(amido amine)s for highly efficient gene delivery. , 2007, Bioconjugate chemistry.

[47]  Justin Hanes,et al.  Privileged delivery of polymer nanoparticles to the perinuclear region of live cells via a non-clathrin, non-degradative pathway. , 2007, Biomaterials.

[48]  L. Sartore,et al.  Degradation behaviour of ionic stepwise polyaddition polymers of medical interest. , 1995, Journal of biomaterials science. Polymer edition.

[49]  D. Sgouras,et al.  Poly(amidoamine)s with potential as drug carriers: degradation and cellular toxicity. , 1991, Journal of biomaterials science. Polymer edition.