Conflicts at the heart of the FRAX tool

Although the presence of osteoporosis, on average, predicts future fractures at the population level, accumulating evidence indicates that both the identification of fracture-prone individuals and the effectiveness of bone-targeted medications in preventing fractures are limited. In fact, most

[1]  E. M. Lewiecki,et al.  Clinician’s Guide to Prevention and Treatment of Osteoporosis , 2014, Osteoporosis International.

[2]  Kim Brixen,et al.  Risk assessment tools to identify women with increased risk of osteoporotic fracture: Complexity or simplicity? A systematic review , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[3]  J. Kanis,et al.  Incidence of Hip Fracture in Romania and the Development of a Romanian FRAX Model , 2013, Calcified Tissue International.

[4]  C. Seife.  Is drug research trustworthy? The pharmaceutical industry funnels money to prominent scientists who are doing research that affects its products--and nobody can stop it. , 2012, Scientific American.

[5]  C. Seife.  Is drug research trustworthy , 2012 .

[6]  Fordyce Re,et al.  The strangest bird: recent fossil discoveries reveal the surprising evolutionary history of penguins. , 2012 .

[7]  Gary S Collins,et al.  Fracture Risk Assessment: State of the Art, Methodologically Unsound, or Poorly Reported? , 2012, Current Osteoporosis Reports.

[8]  C. Cooper,et al.  Interpretation and use of FRAX in clinical practice , 2011, Osteoporosis International.

[9]  S. Cummings,et al.  Estimates of the Proportion of Older White Women Who Would Be Recommended for Pharmacologic Treatment by the New U.S. National Osteoporosis Foundation Guidelines , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[10]  O. Johnell,et al.  FRAX™ and the assessment of fracture probability in men and women from the UK , 2008, Osteoporosis International.

[11]  Ari Heinonen,et al.  Shifting the focus in fracture prevention from osteoporosis to falls , 2008, BMJ : British Medical Journal.