Structure-Based Design and Synthesis of Dipeptide Analogues as New Inhibitors of Leucine Aminopeptidase
暂无分享,去创建一个
[1] J. Grembecka,et al. Leucine aminopeptidase as a target for inhibitor design. , 2001, Mini reviews in medicinal chemistry.
[2] V. Dive,et al. Protection of the Hydroxyphosphinyl Function of Phosphinic Dipeptides by Adamantyl. Application to the Solid-Phase Synthesis of Phosphinic Peptides. , 1996, The Journal of organic chemistry.
[3] W. Lipscomb,et al. Two-metal ion mechanism of bovine lens leucine aminopeptidase: active site solvent structure and binding mode of L-leucinal, a gem-diolate transition state analogue, by X-ray crystallography. , 1995, Biochemistry.
[4] W. Lipscomb,et al. Transition state analogue L-leucinephosphonic acid bound to bovine lens leucine aminopeptidase: X-ray structure at 1.65 A resolution in a new crystal form. , 1995, Biochemistry.
[5] W. Lipscomb,et al. X-ray crystallographic determination of the structure of bovine lens leucine aminopeptidase complexed with amastatin: formulation of a catalytic mechanism featuring a gem-diolate transition state. , 1993, Biochemistry.
[6] A. Taylor. Aminopeptidases: towards a mechanism of action. , 1993, Trends in biochemical sciences.
[7] Hans-Joachim Böhm,et al. LUDI: rule-based automatic design of new substituents for enzyme inhibitor leads , 1992, J. Comput. Aided Mol. Des..
[8] P. Bartlett,et al. Phosphorus amino acid analogues as inhibitors of leucine aminopeptidase. , 1987, Journal of medicinal chemistry.
[9] A B Shenvi,et al. alpha-Aminoboronic acid derivatives: effective inhibitors of aminopeptidases. , 1986, Biochemistry.
[10] C. Hassall. Medicinal chemistry advances: Edited by F. G. De Las Heras and S. Vega. Pp. 512. Pergamon Press, Oxford. 1981. £33.00 , 1983 .
[11] R. Wolfenden,et al. alpha-aminoaldehydes: transition state analogue inhibitors of leucine aminopeptidase. , 1982, Biochemistry.
[12] H. Tschesche. Proteolytic Enzyme Inhibitors , 1981 .
[13] T. Aoyagi,et al. Amastatin, an inhibitor of aminopeptidase A, produced by actinomycetes. , 1978, The Journal of antibiotics.
[14] T. Aoyagi,et al. Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. , 1976, The Journal of antibiotics.