The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators.

[1]  G M Kasof,et al.  Livin, a Novel Inhibitor of Apoptosis Protein Family Member* , 2001, The Journal of Biological Chemistry.

[2]  D. Maier,et al.  Dynamic expression of Drosophila TRAF1 during embryogenesis and larval development , 2001, Mechanisms of Development.

[3]  M. Eby,et al.  The Ectodermal Dysplasia Receptor Activates the Nuclear Factor-κB, JNK, and Cell Death Pathways and Binds to Ectodysplasin A* , 2001, The Journal of Biological Chemistry.

[4]  Zhong-Ping Feng,et al.  Cross-talk between G-protein and Protein Kinase C Modulation of N-type Calcium Channels Is Dependent on the G-protein β Subunit Isoform* , 2000, The Journal of Biological Chemistry.

[5]  S. Srinivasula,et al.  Activation of the IκB Kinases by RIP via IKKγ/NEMO-mediated Oligomerization* , 2000, The Journal of Biological Chemistry.

[6]  Hiroshi Takayanagi,et al.  T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ , 2000, Nature.

[7]  G. Salvesen,et al.  ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas , 2000, Current Biology.

[8]  K. Matsumoto,et al.  ASK1 Inhibits Interleukin-1-induced NF-κB Activity through Disruption of TRAF6-TAK1 Interaction* , 2000, The Journal of Biological Chemistry.

[9]  Zhijian J. Chen,et al.  Activation of the IκB Kinase Complex by TRAF6 Requires a Dimeric Ubiquitin-Conjugating Enzyme Complex and a Unique Polyubiquitin Chain , 2000, Cell.

[10]  Peter Jackson,et al.  The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases. , 2000, Trends in cell biology.

[11]  M. Fenton,et al.  Interleukin-1/Toll receptor family members: receptor structure and signal transduction pathways. , 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[12]  A. Ma,et al.  Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice. , 2000, Science.

[13]  J C Reed,et al.  Molecular basis for CD40 signaling mediated by TRAF3. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[14]  P. Lucas,et al.  An Induced Proximity Model for NF-κB Activation in the Nod1/RICK and RIP Signaling Pathways , 2000 .

[15]  T. Hunter,et al.  The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. , 2000, The Journal of biological chemistry.

[16]  D. Golenbock,et al.  The biology of Toll-like receptors. , 2000, Cytokine & growth factor reviews.

[17]  D. Goeddel,et al.  T6BP, a TRAF6-interacting protein involved in IL-1 signaling. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[18]  P. Scheurich,et al.  Inhibition of Death Receptor-mediated Gene Induction by a Cycloheximide-sensitive Factor Occurs at the Level of or Upstream of Fas-associated Death Domain Protein (FADD)* , 2000, The Journal of Biological Chemistry.

[19]  D. Goeddel,et al.  MIP-T3, a Novel Protein Linking Tumor Necrosis Factor Receptor-associated Factor 3 to the Microtubule Network* , 2000, The Journal of Biological Chemistry.

[20]  C. Thompson,et al.  TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs. , 2000, The American journal of pathology.

[21]  H. Wu,et al.  Thermodynamic characterization of the interaction between TRAF2 and tumor necrosis factor receptor peptides by isothermal titration calorimetry. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[22]  P. Vidalain,et al.  CD40 signaling in human dendritic cells is initiated within membrane rafts , 2000, The EMBO journal.

[23]  J. Treanor,et al.  Taci Is a Traf-Interacting Receptor for Tall-1, a Tumor Necrosis Factor Family Member Involved in B Cell Regulation , 2000, The Journal of experimental medicine.

[24]  Y. E. Chin,et al.  Stat1 as a Component of Tumor Necrosis Factor Alpha Receptor 1-TRADD Signaling Complex To Inhibit NF-κB Activation , 2000, Molecular and Cellular Biology.

[25]  Young Chul Park,et al.  A Novel Mechanism of TRAF Signaling Revealed by Structural and Functional Analyses of the TRADD–TRAF2 Interaction , 2000, Cell.

[26]  K. Tyler,et al.  MEK kinase 1 gene disruption alters cell migration and c-Jun NH2-terminal kinase regulation but does not cause a measurable defect in NF-kappa B activation. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[27]  P. Vandenabeele,et al.  TTRAP, a Novel Protein That Associates with CD40, Tumor Necrosis Factor (TNF) Receptor-75 and TNF Receptor-associated Factors (TRAFs), and That Inhibits Nuclear Factor-κB Activation* , 2000, The Journal of Biological Chemistry.

[28]  D H Tsao,et al.  Solution structure of N-TRADD and characterization of the interaction of N-TRADD and C-TRAF2, a key step in the TNFR1 signaling pathway. , 2000, Molecular cell.

[29]  F. Martinon,et al.  Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor , 2000, Nature Cell Biology.

[30]  G. Bishop,et al.  Recruitment of CD40 and Tumor Necrosis Factor Receptor-associated Factors 2 and 3 to Membrane Microdomains during CD40 Signaling* , 2000, The Journal of Biological Chemistry.

[31]  M. Eby,et al.  TAJ, a Novel Member of the Tumor Necrosis Factor Receptor Family, Activates the c-Jun N-terminal Kinase Pathway and Mediates Caspase-independent Cell Death* , 2000, The Journal of Biological Chemistry.

[32]  G. Nemerow,et al.  MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[33]  Yili Yang,et al.  Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. , 2000, Science.

[34]  T. Honjo,et al.  Alymphoplasia (aly)-Type Nuclear Factor κB–Inducing Kinase (Nik) Causes Defects in Secondary Lymphoid Tissue Chemokine Receptor Signaling and Homing of Peritoneal Cells to the Gut-Associated Lymphatic Tissue System , 2000, The Journal of experimental medicine.

[35]  A. Godzik,et al.  The Drosophila Tumor Necrosis Factor Receptor-associated Factor-1 (DTRAF1) Interacts with Pelle and Regulates NFκB Activity* , 2000, The Journal of Biological Chemistry.

[36]  H. Shu,et al.  Activation of NF-κB by FADD, Casper, and Caspase-8* , 2000, The Journal of Biological Chemistry.

[37]  H. Nakano,et al.  The atypical PKC‐interacting protein p62 channels NF‐κB activation by the IL‐1–TRAF6 pathway , 2000, The EMBO journal.

[38]  K. Yamaguchi,et al.  Requirement of Tumor Necrosis Factor Receptor–Associated Factor (Traf)6 in Interleukin 17 Signal Transduction , 2000, The Journal of experimental medicine.

[39]  K. Irie,et al.  TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. , 2000, Molecular cell.

[40]  M. Kelliher,et al.  The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. , 2000, Immunity.

[41]  G Cantarella,et al.  Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation. , 2000, Immunity.

[42]  J. Tschopp,et al.  Caspase‐induced inactivation of the anti‐apoptotic TRAF1 during Fas ligand‐mediated apoptosis , 2000, FEBS letters.

[43]  M. Lenardo,et al.  A crucial role for p80 TNF‐R2 in amplifying p60 TNF‐R1 apoptosis signals in T lymphocytes , 2000, European journal of immunology.

[44]  F. Urano,et al.  Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. , 2000, Science.

[45]  P. Freemont Ubiquitination: RING for destruction? , 2000, Current Biology.

[46]  A. Leonardi,et al.  Physical and Functional Interaction of Filamin (Actin-binding Protein-280) and Tumor Necrosis Factor Receptor-associated Factor 2* , 2000, The Journal of Biological Chemistry.

[47]  S. Lederman,et al.  TRAF-3 interacts with p62 nucleoporin, a component of the nuclear pore central plug that binds classical NLS-containing import complexes. , 2000, Molecular immunology.

[48]  H. Hanafusa,et al.  TRANCE, a TNF family member, activates Akt/PKB through a signaling complex involving TRAF6 and c-Src. , 1999, Molecular cell.

[49]  D. Baltimore,et al.  NF‐κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK‐related kinase , 1999, The EMBO journal.

[50]  B. Seed,et al.  Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. , 1999, Immunity.

[51]  R. Beyaert,et al.  TRAF1 is a TNF inducible regulator of NF‐κB activation , 1999 .

[52]  D. Payan,et al.  TNIK, a Novel Member of the Germinal Center Kinase Family That Activates the c-Jun N-terminal Kinase Pathway and Regulates the Cytoskeleton* , 1999, The Journal of Biological Chemistry.

[53]  C. Hauser,et al.  TRAF Family Proteins Interact with the Common Neurotrophin Receptor and Modulate Apoptosis Induction* , 1999, The Journal of Biological Chemistry.

[54]  Zhengbin Yao,et al.  Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1) , 1999, Oncogene.

[55]  G. Cheng,et al.  TANK Potentiates Tumor Necrosis Factor Receptor-Associated Factor-Mediated c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase Activation through the Germinal Center Kinase Pathway , 1999, Molecular and Cellular Biology.

[56]  Y. Lin,et al.  Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. , 1999, Genes & development.

[57]  J C Reed,et al.  Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases , 1999, The EMBO journal.

[58]  A. Leonardi,et al.  TNF-mediated activation of the stress-activated protein kinase pathway: TNF receptor-associated factor 2 recruits and activates germinal center kinase related. , 1999, Journal of immunology.

[59]  E. Kieff,et al.  The structural basis for the recognition of diverse receptor sequences by TRAF2. , 1999, Molecular cell.

[60]  R. Paus,et al.  Death deflected: IL‐15 inhibits TNF‐α‐mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL‐15Rα chain , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[61]  C. Janeway,et al.  ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. , 1999, Genes & development.

[62]  T. Alber,et al.  High-affinity interactions of tumor necrosis factor receptor-associated factors (TRAFs) and CD40 require TRAF trimerization and CD40 multimerization. , 1999, Biochemistry.

[63]  R. Ross,et al.  Apoptosis overrides survival signals through a caspase-mediated dominant-negative NF-κB loop , 1999, Nature Cell Biology.

[64]  J. Holton,et al.  Crystallographic analysis of CD40 recognition and signaling by human TRAF2. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[65]  A. Baldwin,et al.  Apoptosis Promotes a Caspase-induced Amino-terminal Truncation of IκBα That Functions as a Stable Inhibitor of NF-κB* , 1999, The Journal of Biological Chemistry.

[66]  Peter Scheurich,et al.  The Human Tumor Necrosis Factor (TNF) Receptor-associated Factor 1 Gene (TRAF1) Is Up-regulated by Cytokines of the TNF Ligand Family and Modulates TNF-induced Activation of NF-κB and c-Jun N-terminal Kinase* , 1999, The Journal of Biological Chemistry.

[67]  G. Stark,et al.  IRAK-M Is a Novel Member of the Pelle/Interleukin-1 Receptor-associated Kinase (IRAK) Family* , 1999, The Journal of Biological Chemistry.

[68]  G. Stark,et al.  Mutant Cells That Do Not Respond to Interleukin-1 (IL-1) Reveal a Novel Role for IL-1 Receptor-Associated Kinase , 1999, Molecular and Cellular Biology.

[69]  R. Geha,et al.  Structure of the murine TRAF1 gene. , 1999, Molecular immunology.

[70]  M. Diaz-Meco,et al.  The interaction of p62 with RIP links the atypical PKCs to NF‐κB activation , 1999, The EMBO journal.

[71]  M. Karin,et al.  Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain. , 1999, Genes & development.

[72]  T. Serikawa,et al.  Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase , 1999, Nature Genetics.

[73]  K. Burns,et al.  Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB. , 1999, The Biochemical journal.

[74]  S. Morony,et al.  TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling. , 1999, Genes & development.

[75]  Michael Karin,et al.  Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation , 1999 .

[76]  Hao Wu,et al.  Structural basis for self-association and receptor recognition of human TRAF2 , 1999, Nature.

[77]  B. Aggarwal,et al.  Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif. , 1999, The Journal of biological chemistry.

[78]  J. Ninomiya-Tsuji,et al.  The kinase TAK1 can activate the NIK-IκB as well as the MAP kinase cascade in the IL-1 signalling pathway , 1999, Nature.

[79]  Guo-liang Yu,et al.  Identification of a Novel Activation-inducible Protein of the Tumor Necrosis Factor Receptor Superfamily and Its Ligand* , 1999, The Journal of Biological Chemistry.

[80]  G. Bren,et al.  Activation of IκB Kinase β by Protein Kinase C Isoforms , 1999, Molecular and Cellular Biology.

[81]  P. Scheurich,et al.  TNF receptor associated factors in cytokine signaling. , 1999, Cytokine & growth factor reviews.

[82]  D. Wallach,et al.  Identification of a cell protein (FIP-3) as a modulator of NF-κB activity and as a target of an adenovirus inhibitor of tumor necrosis factor α-induced apoptosis , 1999 .

[83]  G. Khursigara,et al.  Association of the p75 Neurotrophin Receptor with TRAF6* , 1999, The Journal of Biological Chemistry.

[84]  E. Skolnik,et al.  A Drosophila TNF-receptor-associated factor (TRAF) binds the Ste20 kinase Misshapen and activates Jun kinase , 1999, Current Biology.

[85]  D. Goeddel,et al.  Prevention of constitutive TNF receptor 1 signaling by silencer of death domains. , 1999, Science.

[86]  H. Stein,et al.  Tumor necrosis factor receptor-associated factor 1 is overexpressed in Reed-Sternberg cells of Hodgkin's disease and Epstein-Barr virus-transformed lymphoid cells. , 1999, Blood.

[87]  A. Giordano,et al.  Binding of CDK9 to TRAF2 , 1998, Journal of cellular biochemistry.

[88]  P. Scheurich,et al.  Identification of a TRAF (TNF Receptor-Associated Factor) Gene in Caenorhabditis elegans , 1998, Journal of Molecular Evolution.

[89]  H. Engelmann,et al.  CD40 induces resistance to TNF‐mediated apoptosis in a fibroblast cell line , 1998, European Journal of Immunology.

[90]  R. Steinman,et al.  The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor* , 1998, The Journal of Biological Chemistry.

[91]  P. Scheurich,et al.  TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60. , 1998, Journal of immunology.

[92]  C. Y. Wang,et al.  NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. , 1998, Science.

[93]  K. Miyazono,et al.  ASK1 is essential for JNK/SAPK activation by TRAF2. , 1998, Molecular cell.

[94]  J. Kyriakis,et al.  Tumor Necrosis Factor Signaling to Stress-activated Protein Kinase (SAPK)/Jun NH2-terminal Kinase (JNK) and p38 , 1998, The Journal of Biological Chemistry.

[95]  B. Aggarwal,et al.  Characterization of the intracellular domain of receptor activator of NF-kappaB (RANK). Interaction with tumor necrosis factor receptor-associated factors and activation of NF-kappab and c-Jun N-terminal kinase. , 1998, The Journal of biological chemistry.

[96]  M. Kehry,et al.  CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization. , 1998, Biochemistry.

[97]  F. Martinon,et al.  Identification of CARDIAK, a RIP-like kinase that associates with caspase-1 , 1998, Current Biology.

[98]  V. Dixit,et al.  RIP2 Is a Novel NF-κB-activating and Cell Death-inducing Kinase* , 1998, The Journal of Biological Chemistry.

[99]  M. Boes,et al.  The TNF receptor family member CD27 signals to Jun N‐terminal kinase via Traf‐2 , 1998, European journal of immunology.

[100]  D. Ferrari,et al.  Apoptosis signaling by death receptors. , 1998, European journal of biochemistry.

[101]  Crafford A. Harris,et al.  Interleukin (IL)-1 Receptor–associated Kinase (IRAK) Requirement for Optimal Induction of Multiple IL-1 Signaling Pathways and IL-6 Production , 1998, The Journal of experimental medicine.

[102]  R. Gascoyne,et al.  TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues. , 1998, The American journal of pathology.

[103]  M. Kasahara,et al.  The MHC class I ligand‐generating system: roles of immunoproteasomes and the interferon‐4gMY‐inducible proteasome activator PA28 , 1998, Immunological reviews.

[104]  T. Mak,et al.  CD28-independent, TRAF2-dependent Costimulation of Resting T Cells by 4-1BB Ligand , 1998, The Journal of experimental medicine.

[105]  F. Martinon,et al.  MyD88, an Adapter Protein Involved in Interleukin-1 Signaling* , 1998, The Journal of Biological Chemistry.

[106]  D. Lacey,et al.  Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation , 1998, Cell.

[107]  J C Reed,et al.  IAPs block apoptotic events induced by caspase‐8 and cytochrome c by direct inhibition of distinct caspases , 1998, The EMBO journal.

[108]  Takashi Uchiyama,et al.  Activation of OX40 Signal Transduction Pathways Leads to Tumor Necrosis Factor Receptor-associated Factor (TRAF) 2- and TRAF5-mediated NF-κB Activation* , 1998, The Journal of Biological Chemistry.

[109]  Stefan Grimm,et al.  The Death Domain Kinase RIP Mediates the TNF-Induced NF-κB Signal , 1998 .

[110]  D. Sassoon,et al.  Peg3/Pw1 is an imprinted gene involved in the TNF-NFκB signal transduction pathway , 1998, Nature Genetics.

[111]  H. Lodish,et al.  Tumor Necrosis Factor Receptor (TNFR)-associated Factor 2A (TRAF2A), a TRAF2 Splice Variant with an Extended RING Finger Domain That Inhibits TNFR2-mediated NF-κB Activation* , 1998, The Journal of Biological Chemistry.

[112]  M. Mattei,et al.  Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development , 1998, Mechanisms of Development.

[113]  K. Okazaki,et al.  Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6) Stimulates Extracellular Signal–regulated Kinase (ERK) Activity in CD40 Signaling Along a Ras-independent Pathway , 1998, The Journal of experimental medicine.

[114]  C. Thompson,et al.  4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB , 1998, Molecular and Cellular Biology.

[115]  R. Steinman,et al.  TRANCE (Tumor Necrosis Factor [TNF]-related Activation-induced Cytokine), a New TNF Family Member Predominantly Expressed in T cells, Is a Dendritic Cell–specific Survival Factor , 1997, The Journal of experimental medicine.

[116]  C. Ware,et al.  Dominant Negative Mutants of TRAF3 Reveal an Important Role for the Coiled Coil Domains in Cell Death Signaling by the Lymphotoxin-β Receptor* , 1997, The Journal of Biological Chemistry.

[117]  Z. Cao,et al.  MyD88: an adapter that recruits IRAK to the IL-1 receptor complex. , 1997, Immunity.

[118]  John Calvin Reed,et al.  The c‐IAP‐1 and c‐IAP‐2 proteins are direct inhibitors of specific caspases , 1997, The EMBO journal.

[119]  P. Feng,et al.  IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling. , 1997, Science.

[120]  H. Horvitz,et al.  Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro * , 1997, The Journal of Biological Chemistry.

[121]  R. Dubose,et al.  A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function , 1997, Nature.

[122]  C. Thompson,et al.  CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival. , 1997, Genes & development.

[123]  D. Goeddel,et al.  Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice. , 1997, Immunity.

[124]  D. Goeddel,et al.  Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[125]  P. Scheurich,et al.  Organization of the human tumour necrosis factor receptor-associated factor 1 (TRAF1) gene and mapping to chromosome 9q33-34. , 1997, Gene.

[126]  Guy S. Salvesen,et al.  X-linked IAP is a direct inhibitor of cell-death proteases , 1997, Nature.

[127]  T. Ayres,et al.  Herpesvirus Entry Mediator, a Member of the Tumor Necrosis Factor Receptor (TNFR) Family, Interacts with Members of the TNFR-associated Factor Family and Activates the Transcription Factors NF-κB and AP-1* , 1997, The Journal of Biological Chemistry.

[128]  W. J. Boyle,et al.  ATAR, a Novel Tumor Necrosis Factor Receptor Family Member, Signals through TRAF2 and TRAF5* , 1997, The Journal of Biological Chemistry.

[129]  T. Mak,et al.  Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily. , 1997, Biochemical and biophysical research communications.

[130]  Soo Young Lee,et al.  TRAF-interacting Protein (TRIP): A Novel Component of the Tumor Necrosis Factor Receptor (TNFR)- and CD30-TRAF Signaling Complexes That Inhibits TRAF2-mediated NF-κB Activation , 1997, The Journal of experimental medicine.

[131]  E. Kieff,et al.  Lymphotoxin-β receptor signaling complex: Role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor κB , 1997 .

[132]  D. Wallach,et al.  MAP3K-related kinase involved in NF-KB induction by TNF, CD95 and IL-1 , 1997, Nature.

[133]  Ko Okumura,et al.  Tumor Necrosis Factor Receptor-associated Factor (TRAF) 5 and TRAF2 Are Involved in CD30-mediated NFκB Activation* , 1997, The Journal of Biological Chemistry.

[134]  Minoru Takagi,et al.  Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways , 1997, Science.

[135]  D. Goeddel,et al.  The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[136]  Zhaodan Cao,et al.  TRAF6 is a signal transducer for interleukin-1 , 1996, Nature.

[137]  J. Inoue,et al.  TRAF5, a novel tumor necrosis factor receptor-associated factor family protein, mediates CD40 signaling. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[138]  D. Goeddel,et al.  I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[139]  D. Vaux,et al.  TRAF proteins and meprins share a conserved domain. , 1996, Trends in biochemical sciences.

[140]  D. Goeddel,et al.  The tumor necrosis factor-inducible zinc finger protein A20 interacts with TRAF1/TRAF2 and inhibits NF-kappaB activation. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[141]  C. Ware,et al.  TRAF5, an Activator of NF-κB and Putative Signal Transducer for the Lymphotoxin-β Receptor* , 1996, The Journal of Biological Chemistry.

[142]  D. Baltimore,et al.  TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation. , 1996, Genes & development.

[143]  D. Goeddel,et al.  TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. , 1996, Immunity.

[144]  Soo-Young Lee,et al.  T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors , 1996, The Journal of experimental medicine.

[145]  Hong-Bing Shu,et al.  TRADD–TRAF2 and TRADD–FADD Interactions Define Two Distinct TNF Receptor 1 Signal Transduction Pathways , 1996, Cell.

[146]  K. Tamai,et al.  Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes , 1996, Nature.

[147]  Mike Rothe,et al.  The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins , 1995, Cell.

[148]  George Kollias,et al.  The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor , 1995, Cell.

[149]  P. Basset,et al.  Presence of a New Conserved Domain in CART1, a Novel Member of the Tumor Necrosis Factor Receptor-associated Protein Family, Which Is Expressed in Breast Carcinoma (*) , 1995, The Journal of Biological Chemistry.

[150]  D. Donner,et al.  Association of a RING finger protein with the cytoplasmic domain of the human type-2 tumour necrosis factor receptor. , 1995, The Biochemical journal.

[151]  M. Tewari,et al.  Activation of the B-cell Surface Receptor CD40 Induces A20, a Novel Zinc Finger Protein That Inhibits Apoptosis (*) , 1995, The Journal of Biological Chemistry.

[152]  D. Goeddel,et al.  The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation , 1995, Cell.

[153]  C. Ware,et al.  The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family , 1995, Cell.

[154]  D. Goeddel,et al.  A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor , 1994, Cell.