DNA polymerases and human disease
暂无分享,去创建一个
[1] T. Steitz,et al. Structure of the replicating complex of a pol alpha family DNA polymerase. , 2009, Cell.
[2] 福家 聡,et al. DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice , 2008 .
[3] Joshua M. Korn,et al. Mapping and sequencing of structural variation from eight human genomes , 2008, Nature.
[4] W. Filipowicz,et al. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? , 2008, Nature Reviews Genetics.
[5] D. Scadden,et al. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation , 2008, Nature Reviews Genetics.
[6] M. Pera. Stem cells: A new year and a new era , 2008, Nature.
[7] W. Copeland. Inherited mitochondrial diseases of DNA replication. , 2008, Annual review of medicine.
[8] F. Fabre,et al. DNA Polymerase δ Is Preferentially Recruited during Homologous Recombination To Promote Heteroduplex DNA Extension , 2007, Molecular and Cellular Biology.
[9] J Wade Harper,et al. The DNA damage response: ten years after. , 2007, Molecular cell.
[10] K. Eckert,et al. DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences , 2007, Nucleic acids research.
[11] K. Roemer,et al. Epstein–Barr virus-encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5 , 2007, Nucleic acids research.
[12] S. Gerson,et al. The role of DNA damage repair in aging of adult stem cells , 2007, Nucleic acids research.
[13] John N. Hutchinson,et al. Widespread Monoallelic Expression on Human Autosomes , 2007, Science.
[14] Miki Suzuki,et al. Dynamics of human replication factors in the elongation phase of DNA replication , 2007, Nucleic acids research.
[15] L. Loeb,et al. Mutation at the Polymerase Active Site of Mouse DNA Polymerase δ Increases Genomic Instability and Accelerates Tumorigenesis , 2007, Molecular and Cellular Biology.
[16] Wayne Tam,et al. MicroRNAs in tumorigenesis: a primer. , 2007, The American journal of pathology.
[17] T. Kunkel,et al. Yeast DNA Polymerase ε Participates in Leading-Strand DNA Replication , 2007, Science.
[18] A. Lehmann,et al. Translesion synthesis: Y-family polymerases and the polymerase switch. , 2007, DNA repair.
[19] Irving L. Weissman,et al. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age , 2007, Nature.
[20] Massimo Negrini,et al. MicroRNAs in human cancer: from research to therapy , 2007, Journal of Cell Science.
[21] R. Wells,et al. Non-B DNA conformations, mutagenesis and disease. , 2007, Trends in biochemical sciences.
[22] E. De Clercq,et al. 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells. , 2007, Journal of medicinal chemistry.
[23] S. Jentsch,et al. PCNA, the Maestro of the Replication Fork , 2007, Cell.
[24] E. O’Shea,et al. Living with noisy genes: how cells function reliably with inherent variability in gene expression. , 2007, Annual review of biophysics and biomolecular structure.
[25] M. Esteller. Epigenetic gene silencing in cancer: the DNA hypermethylome. , 2007, Human molecular genetics.
[26] M. O’Donnell,et al. Replisome mechanics: insights into a twin DNA polymerase machine. , 2007, Trends in microbiology.
[27] T. Prolla,et al. Mitochondrial point mutations do not limit the natural lifespan of mice , 2007, Nature Genetics.
[28] Peter A. Jones,et al. The Epigenomics of Cancer , 2007, Cell.
[29] T. Kunkel,et al. A unique error signature for human DNA polymerase nu. , 2007, DNA repair.
[30] Yehia Mechref,et al. A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker , 2006, Proceedings of the National Academy of Sciences.
[31] Lawrence D True,et al. Human cancers express a mutator phenotype , 2006, Proceedings of the National Academy of Sciences.
[32] K. Eckert,et al. DNA Polymerases and Human Diseases , 2006, Radiation research.
[33] E. Argyris,et al. Inhibition of endogenous reverse transcription of human and nonhuman primate lentiviruses: potential for development of lentivirucides. , 2006, Virology.
[34] A. Malhotra,et al. Muscle-specific microRNA miR-206 promotes muscle differentiation , 2006, The Journal of cell biology.
[35] P. Hanawalt,et al. DNA repair: from molecular mechanism to human disease. , 2006, DNA repair.
[36] A. Chatterjee,et al. Mitochondrial DNA mutations in human cancer , 2006, Oncogene.
[37] Samuel H. Wilson,et al. Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. , 2006, Cancer research.
[38] P. Lambin,et al. Lysine 63-Polyubiquitination Guards against Translesion Synthesis–Induced Mutations , 2006, PLoS genetics.
[39] C. Geula,et al. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons , 2006, Nature Genetics.
[40] T. Hudson,et al. Influence of human genome polymorphism on gene expression. , 2006, Human molecular genetics.
[41] S. Salipante,et al. Phylogenetic fate mapping. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[42] E. Kool,et al. Remarkable sensitivity to DNA base shape in the DNA polymerase active site. , 2006, Angewandte Chemie.
[43] Nicholas B. Griner,et al. Mitochondrial DNA integrity is not dependent on DNA polymerase-β activity , 2006 .
[44] N. Maizels. Immunoglobulin gene diversification. , 2005, Annual review of genetics.
[45] D. Wallace. A Mitochondrial Paradigm of Metabolic and Degenerative Diseases, Aging, and Cancer: A Dawn for Evolutionary Medicine , 2005, Annual review of genetics.
[46] U. Hübscher,et al. Phosphorylation of human DNA polymerase λ by the cyclin-dependent kinase Cdk2/cyclin A complex is modulated by its association with proliferating cell nuclear antigen , 2005, Nucleic acids research.
[47] W. Copeland,et al. Consequences of mutations in human DNA polymerase γ , 2005 .
[48] A. Trifunovic,et al. Mitochondrial DNA polymerase gamma is essential for mammalian embryogenesis. , 2005, Human molecular genetics.
[49] T. Hollis,et al. The Human TREX2 3′ → 5′-Exonuclease Structure Suggests a Mechanism for Efficient Nonprocessive DNA Catalysis* , 2005, Journal of Biological Chemistry.
[50] P. Burgers,et al. DNA Polymerases that Propagate the Eukaryotic DNA Replication Fork , 2005, Critical reviews in biochemistry and molecular biology.
[51] I. Bahar,et al. High-efficiency bypass of DNA damage by human DNA polymerase Q. , 2004, The EMBO journal.
[52] S. Benkovic,et al. DNA polymerase fidelity: kinetics, structure, and checkpoints , 2004 .
[53] J. Sweasy,et al. Is There a Link Between DNA Polymerase Beta and Cancer? , 2004, Cell cycle.
[54] A. Lehmann,et al. Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage. , 2004, Molecular cell.
[55] T. Kunkel. DNA Replication Fidelity* , 2004, Journal of Biological Chemistry.
[56] J. Hurwitz,et al. Primer Utilization by DNA Polymerase α-Primase Is Influenced by Its Interaction with Mcm10p* , 2004, Journal of Biological Chemistry.
[57] Sean J. Johnson,et al. Structures of Mismatch Replication Errors Observed in a DNA Polymerase , 2004, Cell.
[58] L. McLaughlin. Faculty Opinions recommendation of Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. , 2004 .
[59] T. Kunkel,et al. Preferential cis–syn thymine dimer bypass by DNA polymerase η occurs with biased fidelity , 2004, Nature.
[60] T. Kunkel,et al. Unique Error Signature of the Four-subunit Yeast DNA Polymerase ϵ* , 2003, Journal of Biological Chemistry.
[61] Samuel H. Wilson,et al. Structural insights into the origins of DNA polymerase fidelity. , 2003, Structure.
[62] Y. Shinkai,et al. Polκ protects mammalian cells against the lethal and mutagenic effects of benzo[a]pyrene , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[63] D. Ramsden,et al. Association of DNA Polymerase μ (pol μ) with Ku and Ligase IV: Role for pol μ in End-Joining Double-Strand Break Repair , 2002, Molecular and Cellular Biology.
[64] J. Stringer,et al. Embryonic stem cells and somatic cells differ in mutation frequency and type , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[65] G. Dianov,et al. Reconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme. , 2002, The Journal of biological chemistry.
[66] C. Limoli,et al. UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, γ-H2AX formation, and Mre11 relocalization , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[67] E. Koonin,et al. Eukaryotic DNA Polymerases: Proposal for a Revised Nomenclature* , 2001, The Journal of Biological Chemistry.
[68] Xiaohua Wu,et al. Accessibility of DNA polymerases to repair synthesis during nucleotide excision repair in yeast cell-free extracts. , 2001, Nucleic acids research.
[69] M. Tagawa,et al. DNA polymerase kappa, implicated in spontaneous and DNA damage-induced mutagenesis, is overexpressed in lung cancer. , 2001, Cancer research.
[70] R. Goldsby,et al. Defective DNA polymerase-δ proofreading causes cancer susceptibility in mice , 2001, Nature Medicine.
[71] Thomas A. Steitz,et al. Structure of the Replicating Complex of a Pol α Family DNA Polymerase , 2001, Cell.
[72] Samuel H. Wilson,et al. 5'-Deoxyribose Phosphate Lyase Activity of Human DNA Polymerase ɩ in Vitro , 2001, Science.
[73] T. Lindahl,et al. Quality control by DNA repair. , 1999, Science.
[74] Chikahide Masutani,et al. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η , 1999, Nature.
[75] Samuel H. Wilson,et al. DNA polymerase β expression differences in selected human tumors and cell lines , 1999 .
[76] O. Popanda,et al. Detection of mutations in the DNA polymerase δ gene of human sporadic colorectal cancers and colon cancer cell lines , 1999, International journal of cancer.
[77] J. Mullins,et al. Lethal mutagenesis of HIV with mutagenic nucleoside analogs. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[78] L. Orgel,et al. Oligomerization of activated D- and L-guanosine mononucleotides on templates containing D- and L-deoxycytidylate residues. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[79] Y. Canitrot,et al. Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[80] P. V. Shcherbakova,et al. 3' -> 5' Exonucleases of DNA Polymerases ε and δ Correct Base Analog Induced DNA Replication Errors on opposite DNA Strands in Saccharomyces Cerevisiae , 1996 .
[81] J. Syväoja,et al. Human DNA polymerase epsilon is expressed during cell proliferation in a manner characteristic of replicative DNA polymerases. , 1995, Nucleic acids research.
[82] R. Jessberger,et al. A mammalian protein complex that repairs double-strand breaks and deletions by recombination. , 1993, The Journal of biological chemistry.
[83] P. Hanawalt,et al. Translesion DNA synthesis in the dihydrofolate reductase domain of UV-irradiated CHO cells. , 1992, Biochemistry.
[84] L. Loeb,et al. Mutator phenotype may be required for multistage carcinogenesis. , 1991, Cancer research.
[85] S. Jain,et al. DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[86] L. Meisner,et al. DNA polymerase alpha defect in the N syndrome. , 1990, American journal of medical genetics.
[87] R. Wood,et al. Complementation of the xeroderma pigmentosum DNA repair defect in cell-free extracts , 1988, Cell.
[88] L. Loeb,et al. Animal Cell Dna Polymerases , 1986 .
[89] M. Goodman,et al. Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[90] T. Mohandas,et al. Assignment of the gene for human DNA polymerase alpha to the X chromosome. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[91] R. Conaway,et al. Synthesis by the DNA primase of Drosophila melanogaster of a primer with a unique chain length. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[92] L. Loeb,et al. Mutagenesis during in vitro DNA synthesis. , 1978, Proceedings of the National Academy of Sciences of the United States of America.
[93] J. Byrnes,et al. A new mammalian DNA polymerase with 3' to 5' exonuclease activity: DNA polymerase delta. , 1976, Biochemistry.
[94] L. Loeb,et al. Errors in DNA replication as a basis of malignant changes. , 1974, Cancer research.
[95] A. Weissbach,et al. The presence of a polyriboadenylic acid-dependent DNA polymerase in eukaryotic cells. , 1972, Archives of biochemistry and biophysics.
[96] L. Chang,et al. Low molecular weight deoxyribonucleic acid polymerase in mammalian cells. , 1971, The Journal of biological chemistry.
[97] A. Weissbach,et al. DNA polymerases from human cells. , 1971, Nature: New biology.
[98] L. Loeb. Purification and properties of deoxyribonucleic acid polymerase from nuclei of sea urchin embryos. , 1969, Journal of Biological Chemistry.
[99] L. Loeb,et al. Induction of DNA polymerase in human lymphocytes by phytohemagglutinin. , 1968, Proceedings of the National Academy of Sciences of the United States of America.
[100] J. Cleaver. Defective Repair Replication of DNA in Xeroderma Pigmentosum , 1968, Nature.
[101] T. Kunkel,et al. The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases , 2008, Cell Research.
[102] T. Kunkel,et al. Yeast DNA polymerase epsilon participates in leading-strand DNA replication. , 2007, Science.
[103] I. Rogozin,et al. Roles of DNA polymerases in replication, repair, and recombination in eukaryotes. , 2006, International review of cytology.
[104] Samuel H. Wilson,et al. Structure and mechanism of DNA polymerase Beta. , 2006, Chemical reviews.
[105] T. Prolla,et al. Mitochondrial DNA integrity is not dependent on DNA polymerase-beta activity. , 2006, DNA Repair.
[106] Christine M Disteche,et al. Dosage compensation of the active X chromosome in mammals , 2006, Nature Genetics.
[107] R. Wood,et al. Loss of DNA polymerase zeta causes chromosomal instability in mammalian cells. , 2006, Cancer research.
[108] T. Eki,et al. Deficiency of the Caenorhabditis elegans DNA polymerase eta homologue increases sensitivity to UV radiation during germ-line development. , 2006, Cell structure and function.
[109] R. Wood,et al. Loss of DNA Polymerase ζ Causes Chromosomal Instability in Mammalian Cells , 2006 .
[110] E. Friedberg,et al. DNA Repair and Mutagenesis , 2006 .
[111] W. Copeland,et al. Consequences of mutations in human DNA polymerase gamma. , 2005, Gene.
[112] J. Hurwitz,et al. Primer utilization by DNA polymerase alpha-primase is influenced by its interaction with Mcm10p. , 2004, Journal of Biological Chemistry.
[113] D. Ramsden,et al. Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair. , 2002, Molecular and cellular biology.
[114] E. G. Frank,et al. 5'-Deoxyribose phosphate lyase activity of human DNA polymerase iota in vitro. , 2001, Science.
[115] R. Goldsby,et al. Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice. , 2001, Nature medicine.
[116] S. H. Wilson,et al. DNA polymerase beta expression differences in selected human tumors and cell lines. , 1999, Carcinogenesis.
[117] P. Modrich,et al. DNA polymerase delta is required for human mismatch repair in vitro. , 1997, The Journal of biological chemistry.
[118] Paul Modrich,et al. DNA Polymerase (cid:100) Is Required for Human Mismatch Repair in Vitro * , 2022 .
[119] P. V. Shcherbakova,et al. 3'-->5' exonucleases of DNA polymerases epsilon and delta correct base analog induced DNA replication errors on opposite DNA strands in Saccharomyces cerevisiae. , 1996, Genetics.
[120] K. Rajewsky,et al. Requirement of mammalian DNA polymerase-beta in base-excision repair. , 1996, Nature.
[121] F. Wedler,et al. Manganese in metabolism and enzyme function , 1986 .
[122] L. Loeb,et al. Chapter 15 - KINETIC AND MAGNETIC RESONANCE STUDIES OF THE INTERACTION OF Mn 2+ , SUBSTRATES AND TEMPLATES WITH DNA POLYMERASES , 1986 .
[123] Thomas A. Kunkel,et al. Rapid and efficient site-specific mutagenesis without phenotypic selection. , 1985, Proceedings of the National Academy of Sciences of the United States of America.