Gene expression microarray analysis in cancer biology, pharmacology, and drug development: progress and potential.
暂无分享,去创建一个
R. Wooster | P. Workman | R. Wooster | P. Clarke | R. T. te Poele | P A Clarke | R te Poele | R Wooster | P Workman | R. Te Poele | R. Poele
[1] H. Beug,et al. Translation control: bridging the gap between genomics and proteomics? , 2001, Trends in biochemical sciences.
[2] S H Kim,et al. Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. , 1998, Science.
[3] E. Southern,et al. Molecular interactions on microarrays , 1999, Nature Genetics.
[4] Yudong D. He,et al. Functional Discovery via a Compendium of Expression Profiles , 2000, Cell.
[5] K. Kinzler,et al. Serial Analysis of Gene Expression , 1995, Science.
[6] P. Brown,et al. Drug target validation and identification of secondary drug target effects using DNA microarrays , 1998, Nature Medicine.
[7] G. Church,et al. Systematic determination of genetic network architecture , 1999, Nature Genetics.
[8] J. V. Moran,et al. Initial sequencing and analysis of the human genome. , 2001, Nature.
[9] P. Deloukas,et al. A Gene Map of the Human Genome , 1996, Science.
[10] John Quackenbush,et al. Gene Index analysis of the human genome estimates approximately 120,000 genes , 2000, Nature Genetics.
[11] M. Bittner,et al. Monitoring the expression profiles of doxorubicin-induced and doxorubicin-resistant cancer cells by cDNA microarray. , 2000, Cancer research.
[12] Mark A. Watson,et al. EGR1 Target Genes in Prostate Carcinoma Cells Identified by Microarray Analysis* , 2000, The Journal of Biological Chemistry.
[13] S. P. Fodor,et al. Light-directed, spatially addressable parallel chemical synthesis. , 1991, Science.
[14] P. Brown,et al. DNA arrays for analysis of gene expression. , 1999, Methods in enzymology.
[15] L. Furness,et al. Pharmacogenomics - it's not just pharmacogenetics. , 1998, Current opinion in biotechnology.
[16] Ash A. Alizadeh,et al. Genome-wide analysis of DNA copy-number changes using cDNA microarrays , 1999, Nature Genetics.
[17] Jutta Heim,et al. Comparative microarray analysis of gene expression during apoptosis-induction by growth factor deprivation or protein kinase C inhibition , 2000, Oncogene.
[18] G. S. Johnson,et al. An Information-Intensive Approach to the Molecular Pharmacology of Cancer , 1997, Science.
[19] P. Workman. Scoring a bull's-eye against cancer genome targets. , 2001, Current opinion in pharmacology.
[20] E. Dougherty,et al. Gene-expression profiles in hereditary breast cancer. , 2001, The New England journal of medicine.
[21] T. Jenssen,et al. A literature network of human genes for high-throughput analysis of gene expression , 2001 .
[22] Preston Hunter,et al. Genome-directed primers for selective labeling of bacterial transcripts for DNA microarray analysis , 2000, Nature Biotechnology.
[23] T R Zacharewski,et al. Assessment of clone identity and sequence fidelity for 1189 IMAGE cDNA clones. , 2001, Nucleic acids research.
[24] Rithy K. Roth,et al. Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays , 2000, Nature Biotechnology.
[25] E Mahlamäki,et al. Hormone therapy failure in human prostate cancer: analysis by complementary DNA and tissue microarrays. , 1999, Journal of the National Cancer Institute.
[26] M. Bittner,et al. Expression profiling using cDNA microarrays , 1999, Nature Genetics.
[27] Michael Bittner,et al. Data analysis and integration: of steps and arrows , 1999, Nature Genetics.
[28] Ash A. Alizadeh,et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling , 2000, Nature.
[29] R. Sam Niedbala,et al. Up-converting phosphor reporters for nucleic acid microarrays , 2001, Nature Biotechnology.
[30] Elaine S. Jaffe,et al. A revised European-American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group. , 1994, Blood.
[31] R. Stoughton,et al. Experimental annotation of the human genome using microarray technology , 2001, Nature.
[32] C. Pilarsky,et al. Microarrays--chances and challenges. , 1999, Current opinion in molecular therapeutics.
[33] David K. Hanzel,et al. Mining the human genome using microarrays of open reading frames , 2000, Nature Genetics.
[34] D. Botstein,et al. Cluster analysis and display of genome-wide expression patterns. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[35] P. Workman,et al. Discovering novel chemotherapeutic drugs for the third millennium. , 1999, European journal of cancer.
[36] Jonathan Knight,et al. When the chips are down , 2001, Nature.
[37] Timothy B. Stockwell,et al. The Sequence of the Human Genome , 2001, Science.
[38] A. Pardee,et al. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. , 1992, Science.
[39] T. Hughes,et al. Signaling and circuitry of multiple MAPK pathways revealed by a matrix of global gene expression profiles. , 2000, Science.
[40] Christian A. Rees,et al. Molecular portraits of human breast tumours , 2000, Nature.
[41] L. Penland,et al. Use of a cDNA microarray to analyse gene expression patterns in human cancer , 1996, Nature Genetics.
[42] T Tanaka,et al. Identification by cDNA microarray of genes involved in ovarian carcinogenesis. , 2000, Cancer research.
[43] J. Styles,et al. Gene expression and amplification in breast carcinoma cells with intrinsic and acquired doxorubicin resistance , 2001, Oncogene.
[44] E. Winzeler,et al. Genomics, gene expression and DNA arrays , 2000, Nature.
[45] Andrius Kazlauskas,et al. Diverse Signaling Pathways Activated by Growth Factor Receptors Induce Broadly Overlapping, Rather Than Independent, Sets of Genes , 1999, Cell.
[46] J. Robert. Resistance to cytotoxic agents. , 2001, Current opinion in pharmacology.
[47] Z. Szallasi. Gene expression patterns and cancer , 1998, Nature Biotechnology.
[48] E. Jaffe,et al. Detection of differentially expressed genes in lymphomas using cDNA arrays: identification of clusterin as a new diagnostic marker for anaplastic large-cell lymphomas. , 2000, Blood.
[49] J Silvio Gutkind,et al. Distinct pattern of expression of differentiation and growth-related genes in squamous cell carcinomas of the head and neck revealed by the use of laser capture microdissection and cDNA arrays , 2000, Oncogene.
[50] P. Brown,et al. Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[51] J. Hudson,et al. In vivo gene expression profile analysis of human breast cancer progression. , 1999, Cancer research.
[52] M. Boguski,et al. dbEST — database for “expressed sequence tags” , 1993, Nature Genetics.
[53] P. Workman,et al. Innovative cancer drug targets: genomics, transcriptomics and clinomics , 2001, Expert opinion on pharmacotherapy.
[54] J N Weinstein,et al. Identification of epidermal growth factor receptor and c-erbB2 pathway inhibitors by correlation with gene expression patterns. , 1997, Journal of the National Cancer Institute.
[55] M. Dowsett,et al. Preoperative chemotherapy induces apoptosis in early breast cancer , 1997, The Lancet.
[56] D. Botstein,et al. A gene expression database for the molecular pharmacology of cancer , 2000, Nature Genetics.
[57] M. Bittner,et al. Data management and analysis for gene expression arrays , 1998, Nature Genetics.
[58] A Guiseppi-Elie,et al. New developments in microarray technology. , 2001, Current opinion in biotechnology.
[59] S. Gygi,et al. Correlation between Protein and mRNA Abundance in Yeast , 1999, Molecular and Cellular Biology.
[60] N. Sampas,et al. Molecular classification of cutaneous malignant melanoma by gene expression profiling , 2000, Nature.
[61] D. Lockhart,et al. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[62] P. Brown,et al. Comparative genome-scale analysis of gene expression profiles in T cell lymphoma cells during malignant progression using a complementary DNA microarray. , 2001, The American journal of pathology.
[63] C Stratowa,et al. Gene expression profiling in drug discovery and development. , 1999, Current opinion in molecular therapeutics.
[64] P. Workman. New drug targets for genomic cancer therapy: successes, limitations, opportunities and future challenges. , 2001, Current cancer drug targets.
[65] I. Roninson,et al. Pleiotropic resistance to DNA-interactive drugs is associated with increased expression of genes involved in DNA replication, repair, and stress response. , 2000, Cancer research.
[66] D. Botstein,et al. The transcriptional program in the response of human fibroblasts to serum. , 1999, Science.
[67] P. Workman,et al. Gene expression profiling of human colon cancer cells following inhibition of signal transduction by 17-allylamino-17-demethoxygeldanamycin, an inhibitor of the hsp90 molecular chaperone , 2000, Oncogene.
[68] J. Seilhamer,et al. A comparison of selected mRNA and protein abundances in human liver , 1997, Electrophoresis.
[69] M. Bittner,et al. Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses , 1999, Oncogene.
[70] J. Mesirov,et al. Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[71] M. Bittner,et al. Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays. , 1998, Cancer research.
[72] T G Myers,et al. DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90. , 1999, Journal of the National Cancer Institute.
[73] S. P. Fodor,et al. High density synthetic oligonucleotide arrays , 1999, Nature Genetics.
[74] Christian A. Rees,et al. Systematic variation in gene expression patterns in human cancer cell lines , 2000, Nature Genetics.
[75] Hongyue Dai,et al. Widespread aneuploidy revealed by DNA microarray expression profiling , 2000, Nature Genetics.
[76] Ronald W. Davis,et al. A genome-wide transcriptional analysis of the mitotic cell cycle. , 1998, Molecular cell.
[77] M. Jackson,et al. Gene expression profiles of laser-captured adjacent neuronal subtypes , 1999, Nature Medicine.
[78] N. Lee,et al. Identification of c-myc responsive genes using rat cDNA microarray. , 2000, Cancer research.
[79] D. Hanahan,et al. The Hallmarks of Cancer , 2000, Cell.
[80] J. Mesirov,et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. , 1999, Science.
[81] Eric S. Lander,et al. Genomic analysis of metastasis reveals an essential role for RhoC , 2000, Nature.
[82] M. Eisen,et al. Gene expression informatics —it's all in your mine , 1999, Nature Genetics.
[83] R. Young,et al. Biomedical Discovery with DNA Arrays , 2000, Cell.
[84] Roger E Bumgarner,et al. Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. , 2001, Science.
[85] N. Lee,et al. A concise guide to cDNA microarray analysis. , 2000, BioTechniques.
[86] Yudong D. He,et al. Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer , 2001, Nature Biotechnology.
[87] P. Workman,et al. Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis. , 2001, Cancer research.
[88] Michael L. Bittner,et al. cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene. , 1999 .