Neuroethics of Non-primary Brain Computer Interface: Focus on Potential Military Applications

The field of neuroethics has had to adapt rapidly in the face of accelerating technological advancement; a particularly striking example is the realm of Brain-Computer Interface (BCI). A significant source of funding for the development of new BCI technologies has been the United States Department of Defense, and while the predominant focus has been restoration of lost function for those wounded in battle, there is also significant interest in augmentation of function to increase survivability, coordination, and lethality of US combat forces. While restoration of primary motor and sensory function (primary BCI) has been the main focus of research, there has been marked progress in interface with areas of the brain subserving memory and association. Non-Primary BCI has a different subset of potential applications, each of which also carries its own ethical considerations. Given the amount of BCI research funding coming from the Department of Defense, it is particularly important that potential military applications be examined from a neuroethical standpoint.

[1]  Vincent P. Clark,et al.  Mechanisms and Effects of Transcranial Direct Current Stimulation , 2017, Dose-response : a publication of International Hormesis Society.

[2]  Michael R. Winograd,et al.  Review of recent studies and issues regarding the P300-based complex trial protocol for detection of concealed information. , 2013, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[3]  T. Rasmussen,et al.  Military-civilian partnership in device innovation: development, commercialization and application of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA). , 2017, The journal of trauma and acute care surgery.

[4]  Mukesh Dhamala,et al.  Interactions Among the Brain Default-Mode, Salience, and Central-Executive Networks During Perceptual Decision-Making of Moving Dots , 2016, Brain Connect..

[5]  Chuck Goodyear,et al.  The Effects of Transcranial Direct Current Stimulation (tDCS) on Multitasking Throughput Capacity , 2016, Front. Hum. Neurosci..

[6]  Shizhen Zhang,et al.  Bilateral anterior capsulotomy and amygdalotomy for mental retardation with psychiatric symptoms and aggression , 2017, Medicine.

[7]  Mohammad Hassan Moradi,et al.  A new approach for EEG feature extraction in P300-based lie detection , 2009, Comput. Methods Programs Biomed..

[8]  Mohammad Hassan Moradi,et al.  A comparison of methods for ERP assessment in a P300-based GKT. , 2006, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[9]  Charles N. Munyon,et al.  Visual-spatial memory may be enhanced with theta burst deep brain stimulation of the fornix: a preliminary investigation with four cases. , 2015, Brain : a journal of neurology.

[10]  Brian Y. Hwang,et al.  Brain-computer interfaces: military, neurosurgical, and ethical perspective. , 2010, Neurosurgical focus.

[11]  Michael C. Anderson,et al.  Parallel Regulation of Memory and Emotion Supports the Suppression of Intrusive Memories , 2017, The Journal of Neuroscience.

[12]  Marcello Ienca,et al.  Towards new human rights in the age of neuroscience and neurotechnology , 2017, Life Sciences, Society and Policy.

[13]  Liyang Sai,et al.  Detecting concealed information using feedback related event-related brain potentials , 2014, Brain and Cognition.

[14]  A. Lozano,et al.  Cosmetic neurosurgery, ethics, and enhancement. , 2015, The lancet. Psychiatry.

[15]  R. Goodman,et al.  Responsive neurostimulation for the treatment of epilepsy. , 2011, Neurosurgery clinics of North America.

[16]  S. Floresco,et al.  Separate Prefrontal-Subcortical Circuits Mediate Different Components of Risk-Based Decision Making , 2012, The Journal of Neuroscience.

[17]  Jennifer Vannest,et al.  Functional MRI-navigated Repetitive Transcranial Magnetic Stimulation Over Supplementary Motor Area in Chronic Tic Disorders , 2014, Brain Stimulation.

[18]  B. Fischer Lessons Learned. , 2016, Schizophrenia bulletin.

[19]  B. Starnes,et al.  Lessons learned from modern military surgery. , 2007, The Surgical clinics of North America.

[20]  Jean A. Orman,et al.  Military-to-civilian translation of battlefield innovations in operative trauma care. , 2015, Surgery.

[21]  Steven E Hyman Emerging Neurotechnologies for Lie-Detection: Where Are We Now? An Appraisal of Wolpe, Foster and Langleben's “Emerging Neurotechnologies for Lie-Detection: Promise and Perils” Five Years Later , 2010, The American journal of bioethics : AJOB.

[22]  Wei Zhao,et al.  Preliminary findings in ablating the nucleus accumbens using stereotactic surgery for alleviating psychological dependence on alcohol , 2010, Neuroscience Letters.

[23]  A. Mincic Neuroanatomical correlates of negative emotionality-related traits: A systematic review and meta-analysis , 2015, Neuropsychologia.

[24]  Xiao Pan Ding,et al.  Detecting Concealed Information Using Functional Near-Infrared Spectroscopy , 2014, Brain Topography.

[25]  Xiaohong Lin,et al.  Novel, ERP-based, concealed information detection: Combining recognition-based and feedback-evoked ERPs , 2016, Biological Psychology.

[26]  Justin C. Sanchez,et al.  DARPA-funded efforts in the development of novel brain–computer interface technologies , 2015, Journal of Neuroscience Methods.

[27]  H. Redkey,et al.  A new approach. , 1967, Rehabilitation record.

[28]  G. J. Annas Military medical ethics--physician first, last, always. , 2008, The New England journal of medicine.

[29]  R Cameron Craddock,et al.  A whole brain fMRI atlas generated via spatially constrained spectral clustering , 2012, Human brain mapping.

[30]  J. Giordano,et al.  Integrating Brain Science and Law: Neuroscientific Evidence and Legal Perspectives on Protecting Individual Liberties , 2017, Front. Neurosci..

[31]  S. Xenakis,et al.  Roles of CIA physicians in enhanced interrogation and torture of detainees. , 2010, JAMA.

[32]  M. Balfe Standardizing psycho-medical torture during the War on Terror: Why it happened, how it happened, and why it didn't work. , 2016, Social science & medicine.