Detection of Cancer Biomarkers with Nanotechnology

Early detection of cancer biomarkers with high prec ision is critically important for cancer therapy. A variety of sensors based on different nanostructured materi als have attracted intensive research interest due to their potential for highly sensitive and selective detect ion of cancer biomarkers. This review covers the us e of a variety of nanostructured materials, including carb on nanotubes, silicon nanowires, gold nanoparticles and quantum dots, in the fabrication of sensors. Emphas es are placed on how the detection systems work and what detection limits can be achieved. Some assays described in this review outperform established methods for cancer biomarker detection. It is highl y promising that these sensors would soon move into commercial-scale production and find routine use in hospitals.

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