Properties of artificial membrane functionalized with sugar

The properties of monolayer of mixed p-10,12- pentacosadiynoic acid (PDA)/p-10,12-pentacosadiyne-1-N- 3,6,9-trioxaundecyl-a-D-mannopyranoside (MPDA) were studied. The monolayer of mixed PDA/MPDA could be recognized by Escherichia coli (E.coli) K12. When incubating with E.coli K12, the color of monolayer changed from blue to red. The response is selective, and can be quantified by visible absorption spectrophotometry.