Bayesian Partitioning for Estimating Disease Risk

This paper presents a Bayesian nonlinear approach for the analysis of spatial count data. It extends the Bayesian partition methodology of Holmes, Denison, and Mallick (1999, Bayesian partitioning for classification and regression, Technical Report, Imperial College, London) to handle data that involve counts. A demonstration involving incidence rates of leukemia in New York state is used to highlight the methodology. The model allows us to make probability statements on the incidence rates around point sources without making any parametric assumptions about the nature of the influence between the sources and the surrounding location.

[1]  Jack Cuzick,et al.  Geographical and environmental epidemiology : methods for small-area studies , 1997 .

[2]  J. Heikkinen Curve and Surface Estimation Using Dynamic Step Functions , 1998 .

[3]  L. Wasserman,et al.  Computing Bayes Factors by Combining Simulation and Asymptotic Approximations , 1997 .

[4]  On the Analysis of Mortality Events Associated with a Prespecified , 1993 .

[5]  W. K. Hastings,et al.  Monte Carlo Sampling Methods Using Markov Chains and Their Applications , 1970 .

[6]  J. Heikkinen,et al.  Non‐parametric Bayesian Estimation of a Spatial Poisson Intensity , 1998 .

[7]  J. Bithell Statistical methods for analysing point-source exposures , 1996 .

[8]  J. Hartigan,et al.  A Bayesian Analysis for Change Point Problems , 1993 .

[9]  Noel A Cressie,et al.  Statistics for Spatial Data. , 1992 .

[10]  P. Diggle,et al.  Non-parametric estimation of spatial variation in relative risk. , 1995, Statistics in medicine.

[11]  L Knorr-Held,et al.  Modelling categorical covariates in Bayesian disease mapping by partition structures. , 2000, Statistics in medicine.

[12]  A. Lawson On the analysis of mortality events associated with a prespecified fixed point. , 1993, Journal of the Royal Statistical Society. Series A,.

[13]  Adrian F. M. Smith,et al.  Sampling-Based Approaches to Calculating Marginal Densities , 1990 .

[14]  Adrian E. Raftery,et al.  Accounting for Model Uncertainty in Survival Analysis Improves Predictive Performance , 1995 .

[15]  J. Heikkinen,et al.  Modeling a Poisson forest in variable elevations: a nonparametric Bayesian approach. , 1999, Biometrics.

[16]  Assessment of disease risk in relation to a pre-specified source , 2001 .

[17]  B. Mallick,et al.  Space-time modelling without distanceD , 1998 .

[18]  Adrian F. M. Smith,et al.  Bayesian Inference for Generalized Linear and Proportional Hazards Models Via Gibbs Sampling , 1993 .

[19]  D. Clayton,et al.  Empirical Bayes estimates of age-standardized relative risks for use in disease mapping. , 1987, Biometrics.

[20]  P. Diggle,et al.  Regression Modelling of Disease Risk in Relation to Point Sources , 1997 .

[21]  Robin Sibson,et al.  Computing Dirichlet Tessellations in the Plane , 1978, Comput. J..

[22]  Robert Haining,et al.  Statistics for spatial data: by Noel Cressie, 1991, John Wiley & Sons, New York, 900 p., ISBN 0-471-84336-9, US $89.95 , 1993 .

[23]  L Knorr-Held,et al.  Bayesian Detection of Clusters and Discontinuities in Disease Maps , 2000, Biometrics.

[24]  J. Besag,et al.  Bayesian image restoration, with two applications in spatial statistics , 1991 .

[25]  Bani K. Mallick,et al.  Bayesian wavelet networks for nonparametric regression , 2000, IEEE Trans. Neural Networks Learn. Syst..