EVAP: A two-photon imaging tool to study conformational changes in endogenous Kv2 channels in live tissues

Thapa et al. present a method to label Kv2 potassium channels in live tissue using a variant of the tarantula toxin guangxitoxin-1E and to image them using two-photon microscopy. Their approach enables the inference of conformational changes in situ from changes in fluorescence intensity.

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