Combination of linkage mapping and microarray-expression analysis identifies NF-kappaB signaling defect as a cause of autosomal-recessive mental retardation.

[1]  J. Gécz,et al.  Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation. , 2008, American journal of human genetics.

[2]  H. Ropers,et al.  A defect in the TUSC3 gene is associated with autosomal recessive mental retardation. , 2008, American journal of human genetics.

[3]  Benjamin R. Rost,et al.  A defect in the ionotropic glutamate receptor 6 gene (GRIK2) is associated with autosomal recessive mental retardation. , 2007, American journal of human genetics.

[4]  H. Hennies,et al.  A new locus for autosomal recessive non‐syndromic mental retardation maps to 1p21.1–p13.3 , 2007, Clinical genetics.

[5]  Wei Chen,et al.  Homozygosity mapping in consanguineous families reveals extreme heterogeneity of non-syndromic autosomal recessive mental retardation and identifies 8 novel gene loci , 2007, Human Genetics.

[6]  A. Routtenberg,et al.  Evolutionarily‐conserved role of the NF‐κB transcription factor in neural plasticity and memory , 2006, The European journal of neuroscience.

[7]  A. Israël,et al.  NF-κB Regulates Spatial Memory Formation and Synaptic Plasticity through Protein Kinase A/CREB Signaling , 2006, Molecular and Cellular Biology.

[8]  C. Walsh,et al.  The CC2D1A, a member of a new gene family with C2 domains, is involved in autosomal recessive non-syndromic mental retardation , 2005, Journal of Medical Genetics.

[9]  Vinay Tergaonkar,et al.  NFκB pathway: A good signaling paradigm and therapeutic target , 2006 .

[10]  S. Mémet.  NF-kappaB functions in the nervous system: from development to disease. , 2006, Biochemical pharmacology.

[11]  T. Gilmore,et al.  Introduction to NF-kappaB: players, pathways, perspectives. , 2006, Oncogene.

[12]  C. Scheidereit.  IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. , 2006, Oncogene.

[13]  V. Tergaonkar.  NFkappaB pathway: a good signaling paradigm and therapeutic target. , 2006, The international journal of biochemistry & cell biology.

[14]  P. Moynagh,et al.  The NF-κB pathway , 2005, Journal of Cell Science.

[15]  B. Barres,et al.  Signaling between glia and neurons: focus on synaptic plasticity , 2005, Current Opinion in Neurobiology.

[16]  W. Walters,et al.  NIBP, a Novel NIK and IKKβ-binding Protein That Enhances NF-κB Activation* , 2005, Journal of Biological Chemistry.

[17]  R. Malenka,et al.  Differential Regulation of AMPA Receptor and GABA Receptor Trafficking by Tumor Necrosis Factor-α , 2005, The Journal of Neuroscience.

[18]  W. Walters,et al.  NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation. , 2005, The Journal of biological chemistry.

[19]  P. Moynagh,et al.  The NF-kappaB pathway. , 2005, Journal of cell science.

[20]  J. Higgins,et al.  A mutation in a novel ATP-dependent Lon protease gene in a kindred with mild mental retardation , 2004, Neurology.

[21]  P. Patterson,et al.  Activation of the IκB Kinase Complex and Nuclear Factor-κB Contributes to Mutant Huntingtin Neurotoxicity , 2004, The Journal of Neuroscience.

[22]  P. Patterson,et al.  Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. , 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[23]  Jae K. Lee,et al.  Local-pooled-error test for identifying differentially expressed genes with a small number of replicated microarrays , 2003, Bioinform..

[24]  B. Carter,et al.  Activation of the transcription factor NF-κB in Schwann cells is required for peripheral myelin formation , 2003, Nature Neuroscience.

[25]  P. Gean,et al.  A Requirement of Nuclear Factor-κB Activation in Fear-potentiated Startle* , 2002, The Journal of Biological Chemistry.

[26]  A. Munnich,et al.  Truncating Neurotrypsin Mutation in Autosomal Recessive Nonsyndromic Mental Retardation , 2002, Science.

[27]  M. Karin,et al.  Missing Pieces in the NF-κB Puzzle , 2002, Cell.

[28]  P. Gean,et al.  A requirement of nuclear factor-kappaB activation in fear-potentiated startle. , 2002, The Journal of biological chemistry.

[29]  R. Malenka,et al.  Control of synaptic strength by glial TNFalpha. , 2002, Science.

[30]  M. Mattson,et al.  Evidence for the involvement of TNF and NF‐κB in hippocampal synaptic plasticity , 2000, Synapse.

[31]  Y Agid,et al.  Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[32]  P. Baeuerle,et al.  Transcription factor NF-κB is activated in primary neurons by amyloid β peptides and in neurons surrounding early plaques from patients with Alzheimer disease , 1997 .

[33]  Nel Roeleveld,et al.  The prevalence of mental retardation: a critical review of recent literature , 1997, Developmental medicine and child neurology.

[34]  P. Baeuerle,et al.  Transcription factor NF-kappaB is activated in primary neurons by amyloid beta peptides and in neurons surrounding early plaques from patients with Alzheimer disease. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[35]  F. Eusebi,et al.  Tumor necrosis factor alters synaptic transmission in rat hippocampal slices , 1992, Neuroscience Letters.