Does Atrial Fibrillation Beget Ventricular Fibrillation in Patients with Acute Myocardial Infarction?

Background: Atrial fibrillation (AF) is associated with increased mortality and a higher complication rate postmyocardial infarction (MI), but the exact mechanisms are unknown. We investigated whether AF predisposes to ventricular arrhythmia in postmyocardial infarct patients, thereby accounting for increased mortality.

[1]  K. Dickstein,et al.  Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience. , 2005, European heart journal.

[2]  G. Gerstenblith,et al.  Ventricular ectopic activity after premature atrial beats in acute myocardial infarction. , 1977, British heart journal.

[3]  M. Codd,et al.  Hospital mortality of acute myocardial infarction in the thrombolytic era , 1999, Heart.

[4]  M. Allessie,et al.  Atrial Electrophysiologic Remodeling: Another Vicious Circle? , 1998, Journal of cardiovascular electrophysiology.

[5]  J. Molnar,et al.  Enhancement of Myocardial Vulnerability by Atrial Fibrillation , 2004, American journal of therapeutics.

[6]  S. Hohnloser,et al.  Association Between Atrial Fibrillation and Appropriate Implantable Cardioverter Defibrillator Therapy:Results from a Prospective Study , 2000, Cardiovascular Electrophysiology.

[7]  J. McMurray,et al.  Antiarrhythmic effect of carvedilol after acute myocardial infarction: results of the Carvedilol Post-Infarct Survival Control in Left Ventricular Dysfunction (CAPRICORN) trial. , 2005, Journal of the American College of Cardiology.

[8]  A. Ehsani,et al.  Ventricular fibrillation threshold in acute myocardial infarction and its relation to myocardial infarct size. , 1975, Cardiovascular research.

[9]  C. Rinaldi,et al.  MYOCARDIAL STUNNING AND HIBERNATION IN CLINICAL PRACTICE , 2000, International journal of clinical practice.

[10]  D. Zipes,et al.  Atrial induction of ventricular tachycardia: reentry versus triggered automaticity. , 1979, The American journal of cardiology.

[11]  B Lown,et al.  Neural activity and ventricular fibrillation. , 1976, The New England journal of medicine.

[12]  R. Kloner,et al.  Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 1. , 2001, Circulation.

[13]  B. Lerman Mechanoelectrical Feedback: Maturation of a Concept , 1996, Journal of cardiovascular electrophysiology.

[14]  R. Califf,et al.  Atrial fibrillation in the setting of acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries. , 1997, Journal of the American College of Cardiology.

[15]  L. Køber,et al.  Increased risk of sudden and non-sudden cardiovascular death in patients with atrial fibrillation/flutter following acute myocardial infarction. , 2006, European heart journal.

[16]  S. Markowitz,et al.  Heart rate changes preceding ventricular ectopy in patients with ventricular tachycardia caused by reentry, triggered activity, and automaticity. , 1998, American heart journal.

[17]  L. Køber,et al.  The occurrence and prognostic significance of atrial fibrillation/-flutter following acute myocardial infarction. TRACE Study group. TRAndolapril Cardiac Evalution. , 1999, European heart journal.

[18]  A. Maggioni,et al.  Incidence and prognostic significance of atrial fibrillation in acute myocardial infarction: the GISSI-3 data , 2001, Heart.

[19]  J. Bigger,et al.  A model of chronic ischemic arrhythmias: the relation between electrically inducible ventricular tachycardia, ventricular fibrillation threshold and myocardial infarct size. , 1982, The American journal of cardiology.

[20]  M. Allessie,et al.  Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats. , 1995, Circulation.

[21]  A. Skene,et al.  Relevance of clinical trial results in myocardial infarction to medical practice: comparison of four year outcome in participants of a thrombolytic trial, patients receiving routine thrombolysis, and those deemed ineligible for thrombolysis , 1999, Heart.

[22]  E. Negri,et al.  Incidence and prognosis of early primary ventricular fibrillation in acute myocardial infarction--results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI-2) database. , 1998, The American journal of cardiology.

[23]  K. Eagle,et al.  Comparison of outcomes of patients with acute coronary syndromes with and without atrial fibrillation. , 2003, The American journal of cardiology.

[24]  A. Raviele Cardiac Arrhythmias 2005 , 2006 .

[25]  Suneet Mittal,et al.  Do atrial tachyarrhythmias beget ventricular tachyarrhythmias in defibrillator recipients? , 2002, Journal of the American College of Cardiology.

[26]  L. Opie Myocardial metabolism and heart disease. , 1978, Japanese circulation journal.

[27]  M. Allessie,et al.  Electrical remodeling due to atrial fibrillation in chronically instrumented conscious goats: roles of neurohumoral changes, ischemia, atrial stretch, and high rate of electrical activation. , 1997, Circulation.

[28]  O. Rimoldi,et al.  Blood flow in myocardial hibernation. , 1998, Current opinion in cardiology.

[29]  R. Califf,et al.  Atrial Fibrillation in the Setting of Acute Myocardial Infarction: The GUSTO-I Experience , 1997 .