Clinical and functional outcomes of patients with a pathologic fracture in high‐grade osteosarcoma

There have been variable reports of outcomes of patients with osteosarcoma and pathologic fractures. The purpose of this study was to document outcomes after management of this clinical entity at a single large oncology center.

[1]  D. Jeon,et al.  Prognostic effect of pathologic fracture in localized osteosarcoma: A cohort/case controlled study at a single institute , 2009, Journal of surgical oncology.

[2]  X. Niu,et al.  [The surgical treatment and outcome of nonmetastatic osteosarcoma of the extremity with pathologic fractures]. , 2008, Zhonghua wai ke za zhi [Chinese journal of surgery].

[3]  B. Fuchs,et al.  Cathepsins and osteosarcoma: Expression analysis identifies cathepsin K as an indicator of metastasis , 2008, Molecular carcinogenesis.

[4]  R. Grimer,et al.  Do pathological fractures influence survival and local recurrence rate in bony sarcomas? , 2007, European journal of cancer.

[5]  C. Bombardier,et al.  Development of a measure of physical function for patients with bone and soft tissue sarcoma , 1996, Quality of Life Research.

[6]  S. Ferrari,et al.  Nonmetastatic osteosarcoma of the extremity with pathologic fracture at presentationLocal and systemic control by amputation or limb salvage after preoperative chemotherapy , 2003, Acta orthopaedica Scandinavica.

[7]  D. Zurakowski,et al.  Pathologic Fracture in Osteosarcoma: Prognostic Importance and Treatment Implications , 2002, The Journal of bone and joint surgery. American volume.

[8]  S. Williams,et al.  Limb salvage surgery for pathological fractures in osteosarcoma , 2000, International Orthopaedics.

[9]  R. Grimer,et al.  The surgical treatment and outcome of pathological fractures in localised osteosarcoma. , 1996, The Journal of bone and joint surgery. British volume.

[10]  S. Scully,et al.  The Surgical Treatment of Patients With Osteosarcoma Who Sustain a Pathologic Fracture , 1996, Clinical orthopaedics and related research.

[11]  N. Jaffe,et al.  Pathologic fracture in osteosarcoma. Impact of chemotherapy on primary tumor and survival , 1987, Cancer.

[12]  Dahlin Dc Osteosarcoma of bone and a consideration of prognostic variables. , 1978 .

[13]  H. Woodard,et al.  An analysis of thirty patients surviving longer than ten years after treatment for osteogenic sarcoma. , 1968, The Journal of bone and joint surgery. American volume.