A microchemical facility for the analysis and synthesis of genes and proteins

[1]  L. Hood,et al.  Separation of peptides by reverse-phase high-performance liquid chromatography using propyl- and cyanopropylsilyl supports. , 1984, Analytical biochemistry.

[2]  L. Hood,et al.  Protein sequence analysis: automated microsequencing. , 1983, Science.

[3]  L. Hood,et al.  Isolation of microgram quantities of proteins from polyacrylamide gels for amino acid sequence analysis. , 1983, Methods in enzymology.

[4]  Eric O Long,et al.  A molecular map of the immune response region from the major histocompatibility complex of the mouse , 1982, Nature.

[5]  A. Riggs,et al.  Oligonucleotide-directed mutagenesis as a general and powerful method for studies of protein function. , 1982, Proceedings of the National Academy of Sciences of the United States of America.

[6]  Richard A. Lerner,et al.  Tapping the immunological repertoire to produce antibodies of predetermined specificity , 1982, Nature.

[7]  C. Birr Chemical synthesis and sequencing of peptides and proteins: edited by T. Liu, A. Schechter, R. Heinrikson and P. Condlippe, Elsevier/North-Holland, 1981. $50.00/ Dfl. 125.00 (xxv+ 274 pages) ISBN 0 444 00623 0 , 1982 .

[8]  L. Hood,et al.  Clusters of genes encoding mouse transplantation antigens , 1982, Cell.

[9]  E. Kawashima,et al.  Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[10]  C. Milstein,et al.  Complete sequence of an immunoglobulin mRNA using specific priming and the dideoxynucleotide method of RNA sequencing. , 1981, Nucleic acids research.

[11]  L. Hood,et al.  A gas-liquid solid phase peptide and protein sequenator. , 1981, The Journal of biological chemistry.

[12]  M. Caruthers,et al.  Synthesis of deoxyoligonucleotides on a polymer support , 1981 .

[13]  L. Hood,et al.  Three cDNA clones encoding mouse transplantation antigens: Homology to immunoglobulin genes , 1981, Cell.

[14]  J Messing,et al.  A system for shotgun DNA sequencing. , 1981, Nucleic acids research.

[15]  M. Caruthers,et al.  Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis , 1981 .

[16]  J. G. Sutcliffe,et al.  Chemical synthesis of a polypeptide predicted from nucleotide sequence allows detection of a new retroviral gene product , 1980, Nature.

[17]  F. Sanger,et al.  Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing. , 1980, Journal of molecular biology.

[18]  K. Scheidtmann,et al.  Antibodies specific for the carboxy- and amino-terminal regions of simian virus 40 large tumor antigen. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[19]  R. B. Merrifield,et al.  Properties of swollen polymer networks. Solvation and swelling of peptide-containing resins in solid-phase peptide synthesis , 1980 .

[20]  K. Gibson,et al.  Supports for reverse-phase high-performance liquid chromatography of large proteins. , 1980, Analytical biochemistry.

[21]  M. Engelhard,et al.  Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[22]  M. Mevarech,et al.  Detection and partial sequence analysis of gastrin mRNA by using an oligodeoxynucleotide probe. , 1979, Proceedings of the National Academy of Sciences of the United States of America.

[23]  G. Tarr,et al.  Polyquarternary amines prevent peptide loss from sequenators. , 1978, Analytical biochemistry.

[24]  C. McMartin,et al.  Use of octadecasilyl-silica for the extraction and purification of peptides in biological samples. Application to the identification of circulating metabolites of corticotropin-(1-24)-tetracosapeptide and somatostatin in vivo. , 1977, The Biochemical journal.

[25]  P. O’Farrell High resolution two-dimensional electrophoresis of proteins. , 1975, The Journal of biological chemistry.

[26]  C. Giffin,et al.  An electro—optical detector for focal plane mass spectrometers , 1974 .

[27]  W. Dreyer,et al.  Automatic mass-spectrometric analysis: preliminary report on development of novel mass-spectrometric system for biomedical applications. , 1974, Clinical chemistry.

[28]  M. Caruthers,et al.  CIII. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast , 1972 .

[29]  P. Edman,et al.  A protein sequenator. , 1967, European journal of biochemistry.

[30]  H. I. Waterman,et al.  On the Mechanism of the Phenyl Isothiocyanate Degradation of Peptides. , 1956 .