Monitoring silver diamine fluoride application with optical coherence tomography

This study investigated the utility of using OCT to monitor SDF application over time. Twenty dentin blocks each with 5 windows were exposed to a demineralization solution to produce carious lesions. Treatment windows included sound, sound+SDF, lesion, lesion+SDF, lesion+SDF+SDF. Lesion depth, mean reflectivity over the lesion depth and optical penetration through the lesions were monitored with OCT for 12 weeks. OCT was able to show changes in the reflectivity and optical penetration in demineralized and sound dentin after SDF application over time. Such changes can potentially be monitored to determine if and when re-application of SDF is needed.

[1]  Hobin Kang,et al.  Longitudinal monitoring of demineralization peripheral to orthodontic brackets using cross polarization optical coherence tomography. , 2014, Journal of dentistry.

[2]  Daniel Fried,et al.  Nondestructive assessment of dentin demineralization using polarization-sensitive optical coherence tomography after exposure to fluoride and laser irradiation. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[3]  Kenneth H. Chan,et al.  Multispectral cross-polarization reflectance measurements suggest high contrast of demineralization on tooth surfaces at wavelengths beyond 1300 nm due to reduced light scattering in sound enamel. , 2018, Journal of biomedical optics.

[4]  M. Burrow,et al.  3D imaging of proximal caries in posterior teeth using optical coherence tomography , 2020, Scientific Reports.

[5]  Daniel Fried,et al.  Clinical assessment of early tooth demineralization using polarization sensitive optical coherence tomography , 2010, Lasers in surgery and medicine.

[6]  Daniel Fried,et al.  Polarization-sensitive optical coherence tomographic imaging of artificial demineralization on exposed surfaces of tooth roots. , 2009, Dental materials : official publication of the Academy of Dental Materials.

[7]  Daniel Fried,et al.  Clinical monitoring of early caries lesions using cross polarization optical coherence tomography , 2013, Photonics West - Biomedical Optics.

[8]  I. Yokomizo,et al.  Diammine silver fluoride and its clinical application. , 1972, The Journal of Osaka University Dental School.

[9]  J. Mellberg.  Hard-tissue Substrates for Evaluation of Cariogenic and Anti-cariogenic Activity in situ , 1992, Journal of dental research.

[10]  Daniel Fried,et al.  Imaging caries lesions and lesion progression with polarization-sensitive optical coherence tomography , 2002, SPIE BiOS.

[11]  M. Mei,et al.  Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children , 2016, JDR clinical and translational research.

[12]  C. Chu,et al.  Effectiveness of Silver Diamine Fluoride and Sodium Fluoride Varnish in Arresting Dentin Caries in Chinese Pre-school Children , 2002, Journal of dental research.

[13]  Cláudia C. B. O. Mota,et al.  Silver nanoparticles as optical clearing agent enhancers to improve caries diagnostic by optical coherence tomography , 2018, BiOS.

[14]  B T Amaechi,et al.  Use of optical coherence tomography for assessment of dental caries: quantitative procedure. , 2001, Journal of oral rehabilitation.

[15]  Robert C. Lee,et al.  Non‐destructive clinical assessment of occlusal caries lesions using near‐IR imaging methods , 2011, Lasers in surgery and medicine.

[16]  M. Mei,et al.  An ex vivo study of arrested primary teeth caries with silver diamine fluoride therapy. , 2014, Journal of dentistry.

[17]  Daniel Fried,et al.  Polarization-sensitive optical coherence tomography for the nondestructive assessment of the remineralization of dentin. , 2009, Journal of biomedical optics.

[18]  H. Margolis,et al.  Effect of fluoride on artificial caries lesion progression and repair in human enamel: regulation of mineral deposition and dissolution under in vivo-like conditions. , 2007, Archives of oral biology.

[19]  Ruikang K. Wang,et al.  Propylene glycol as a contrasting agent for optical coherence tomography to image gastrointestinal tissues , 2002, Lasers in surgery and medicine.

[20]  H. Meyer-Lueckel,et al.  Caries-Preventive Effect of NaF, NaF plus TCP, NaF plus CPP-ACP, and SDF Varnishes on Sound Dentin and Artificial Dentin Caries in vitro , 2018, Caries Research.

[21]  J. Horst,et al.  UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent. , 2016, Journal of the California Dental Association.

[22]  Hobin Kang,et al.  Clinical monitoring of smooth surface enamel lesions using CP‐OCT during nonsurgical intervention , 2016, Lasers in surgery and medicine.

[23]  R. Niederman,et al.  Silver Diamine Fluoride: A Caries “Silver-Fluoride Bullet” , 2009, Journal of dental research.

[24]  Daniel Fried,et al.  High-resolution PS-OCT of enamel remineralization , 2008, SPIE BiOS.

[25]  M. Mei,et al.  Arresting Dentine Caries with Silver Diamine Fluoride: What’s Behind It? , 2018, Journal of dental research.