Restriction of food intake prevents postinfarction heart failure by enhancing autophagy in the surviving cardiomyocytes.

[1]  M. Seishima,et al.  Resveratrol reverses remodeling in hearts with large, old myocardial infarctions through enhanced autophagy-activating AMP kinase pathway. , 2013, American Journal of Pathology.

[2]  Takeshi Kimura,et al.  Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice. , 2011, Journal of molecular and cellular cardiology.

[3]  L. Guarente,et al.  SIRT1-mediated acute cardioprotection. , 2011, American journal of physiology. Heart and circulatory physiology.

[4]  M. Seishima,et al.  The role of autophagy emerging in postinfarction cardiac remodelling. , 2011, Cardiovascular research.

[5]  B. Viollet,et al.  AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1 , 2011, Nature Cell Biology.

[6]  B. Viollet,et al.  Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy , 2011, Science.

[7]  Hong-Gang Wang,et al.  The Association of AMPK with ULK1 Regulates Autophagy , 2010, PloS one.

[8]  M. Seishima,et al.  Functional significance and morphological characterization of starvation-induced autophagy in the adult heart. , 2009, The American journal of pathology.

[9]  R. Gottlieb,et al.  Autophagy in Ischemic Heart Disease , 2009, Circulation research.

[10]  B. Turk,et al.  AMPK phosphorylation of raptor mediates a metabolic checkpoint. , 2008, Molecular cell.

[11]  Chengqun Huang,et al.  A method to measure cardiac autophagic flux in vivo , 2008, Autophagy.

[12]  Masaaki Komatsu,et al.  Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice , 2007, Cell.

[13]  C. Leeuwenburgh,et al.  Autophagy in the heart and liver during normal aging and calorie restriction. , 2007, Rejuvenation research.

[14]  Yasushi Matsumura,et al.  The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress , 2007, Nature Medicine.

[15]  T. Aoyama,et al.  Inhibition of Fas-associated apoptosis in granulation tissue cells accompanies attenuation of postinfarction left ventricular remodeling by olmesartan. , 2007, American journal of physiology. Heart and circulatory physiology.

[16]  T. Asano,et al.  Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion: Roles of AMP-Activated Protein Kinase and Beclin 1 in Mediating Autophagy , 2007, Circulation research.

[17]  G. Takemura,et al.  Autophagic Degeneration and Death of Cardiomyocytes in Heart Failure , 2006, Autophagy.

[18]  Lin Yan,et al.  Autophagy in chronically ischemic myocardium. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[19]  Takeshi Tokuhisa,et al.  The role of autophagy during the early neonatal starvation period , 2004, Nature.

[20]  Daniel J. Klionsky,et al.  Autophagy in Health and Disease: A Double-Edged Sword , 2004, Science.

[21]  D. Reinberg,et al.  Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. , 2004, Molecular cell.

[22]  G. Takemura,et al.  Critical Roles for the Fas/Fas Ligand System in Postinfarction Ventricular Remodeling and Heart Failure , 2004, Circulation research.

[23]  C. Bode,et al.  Human hibernating myocardium is jeopardized by apoptotic and autophagic cell death. , 2004, Journal of the American College of Cardiology.

[24]  P. Clarke,et al.  Developmental cell death: morphological diversity and multiple mechanisms , 2004, Anatomy and Embryology.

[25]  K. Inoki,et al.  TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival , 2003, Cell.

[26]  Minyoung Lee,et al.  AMP-activated Protein Kinase Activity Is Critical for Hypoxia-inducible Factor-1 Transcriptional Activity and Its Target Gene Expression under Hypoxic Conditions in DU145 Cells* , 2003, Journal of Biological Chemistry.

[27]  I. Shiojima,et al.  Akt Activity Negatively Regulates Phosphorylation of AMP-activated Protein Kinase in the Heart* , 2003, Journal of Biological Chemistry.

[28]  J. Schaper,et al.  Progression From Compensated Hypertrophy to Failure in the Pressure-Overloaded Human Heart: Structural Deterioration and Compensatory Mechanisms , 2003, Circulation.

[29]  Takeshi Noda,et al.  LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing , 2000, The EMBO journal.

[30]  Tobias Schmelzle,et al.  TOR, a Central Controller of Cell Growth , 2000, Cell.

[31]  P. Seglen,et al.  Inhibition of hepatocytic autophagy by adenosine, aminoimidazole-4-carboxamide riboside, and N6-mercaptopurine riboside. Evidence for involvement of amp-activated protein kinase. , 1998, The Journal of biological chemistry.

[32]  W. Schaper,et al.  Hibernating myocardium: an incomplete adaptation to ischemia. , 1997, Circulation.

[33]  D. Mann,et al.  The role of cytokines in disease progression in heart failure. , 1997, Current opinion in cardiology.

[34]  H. Duff,et al.  Developmental changes in the delayed rectifier K+ channels in mouse heart. , 1996, Circulation research.

[35]  H. Duff,et al.  Effects of intracellular calcium on sodium current density in cultured neonatal rat cardiac myocytes. , 1995, The Journal of physiology.

[36]  A. Meijer,et al.  Phosphorylation of Ribosomal Protein S6 Is Inhibitory for Autophagy in Isolated Rat Hepatocytes (*) , 1995, The Journal of Biological Chemistry.

[37]  M. Pfeffer.  Left ventricular remodeling after acute myocardial infarction. , 1995, Annual review of medicine.

[38]  V. Richard,et al.  Reperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental models. , 1993, The American journal of cardiology.

[39]  M. Weisfeldt,et al.  Cellular mechanisms of myocardial infarct expansion. , 1988, Circulation.

[40]  N. LaRusso,et al.  Effect of chloroquine on the form and function of hepatocyte lysosomes. Morphologic modifications and physiologic alterations related to the biliary excretion of lipids and proteins. , 1983, Gastroenterology.

[41]  B Poole,et al.  Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents. , 1978, Proceedings of the National Academy of Sciences of the United States of America.