Epstein-Barr virus and genetic risk variants as determinants of T-bet+ B cell-driven autoimmune diseases.
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[1] Hali Broncucia,et al. Identification of an anergic BND cell–derived activated B cell population (BND2) in young-onset type 1 diabetes patients , 2023, The Journal of experimental medicine.
[2] S. Gregory,et al. An EBV-associated atypical B cell signature in clinically isolated syndrome is implicated in progression of multiple sclerosis , 2023, medRxiv.
[3] J. Smolders,et al. Selective emergence of antibody-secreting cells in the multiple sclerosis brain , 2023, EBioMedicine.
[4] Vina Fan,et al. Gammaherpesvirus infection drives age-associated B cells toward pathogenicity in EAE and MS , 2022, Science advances.
[5] H. Scherer,et al. Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis , 2022, Arthritis Research & Therapy.
[6] T. White,et al. Multiple sclerosis risk variants influence the peripheral B‐cell compartment early in life in the general population , 2022, European journal of neurology.
[7] M. Luftig,et al. Epstein-Barr virus perpetuates B cell germinal center dynamics and generation of autoimmune-associated phenotypes in vitro , 2022, Frontiers in Immunology.
[8] C. Münz,et al. Altered Immune Response to the Epstein–Barr Virus as a Prerequisite for Multiple Sclerosis , 2022, Cells.
[9] R. Scofield,et al. Polygenic autoimmune disease risk alleles impacting B cell tolerance act in concert across shared molecular networks in mouse and in humans , 2022, Frontiers in Immunology.
[10] P. Lieberman,et al. Epstein–Barr virus and multiple sclerosis , 2022, Nature reviews. Microbiology.
[11] M. Luftig,et al. Time-resolved transcriptomes reveal diverse B cell fate trajectories in the early response to Epstein-Barr virus infection. , 2022, Cell reports.
[12] J. Casanova,et al. Human T-bet governs the generation of a distinct subset of CD11chighCD21low B cells , 2022, Science Immunology.
[13] Lucas E. Wange,et al. EBNA2-EBF1 complexes promote MYC expression and metabolic processes driving S-phase progression of Epstein-Barr virus–infected B cells , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[14] U. Boschert,et al. Human T-bet+ B cell development is associated with BTK activity and suppressed by evobrutinib , 2022, JCI insight.
[15] M. Horwitz,et al. Age-associated B cells in autoimmune diseases , 2022, Cellular and Molecular Life Sciences.
[16] A. Bozec,et al. Age-associated B cells contribute to the pathogenesis of rheumatoid arthritis by inducing activation of fibroblast-like synoviocytes via TNF-α-mediated ERK1/2 and JAK-STAT1 pathways , 2022, Annals of the Rheumatic Diseases.
[17] A. Sawalha,et al. The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope , 2022, Communications Biology.
[18] A. Garyfallos,et al. Involvement of age-associated B cells in EBV-triggered autoimmunity , 2022, Immunologic Research.
[19] Y. Ye,et al. Age-associated B cells indicate disease activity in rheumatoid arthritis. , 2022, Cellular immunology.
[20] M. Horwitz,et al. Age-associated B cells are long-lasting effectors that restrain reactivation of latent γHV68 , 2022, bioRxiv.
[21] Timothy J. Peters,et al. STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological dysregulation of NKG2Dhi CD8 killer T cells , 2022, bioRxiv.
[22] A. Damasceno,et al. Cytotoxic B Cells in Relapsing-Remitting Multiple Sclerosis Patients , 2022, Frontiers in Immunology.
[23] O. Boyman,et al. Systematic Review of Safety and Efficacy of Second- and Third-Generation CD20-Targeting Biologics in Treating Immune-Mediated Disorders , 2022, Frontiers in Immunology.
[24] S. Elledge,et al. Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis , 2022, Science.
[25] A. Perl,et al. Adenosine receptor 2a agonists target mouse CD11c+T-bet+ B cells in infection and autoimmunity , 2022, Nature communications.
[26] N. Hattori,et al. Dysregulated B cell differentiation towards antibody-secreting cells in neuromyelitis optica spectrum disorder , 2022, Journal of Neuroinflammation.
[27] Timothy J. Peters,et al. Overactive STAT3 drives accumulation of disease-associated CD21low B cells , 2021, bioRxiv.
[28] M. Wampole,et al. Bruton’s Tyrosine Kinase (BTK) Inhibitors and Autoimmune Diseases: Making Sense of BTK Inhibitor Specificity Profiles and Recent Clinical Trial Successes and Failures , 2021, Frontiers in Immunology.
[29] J. Casanova,et al. The expansion of human T-bethighCD21low B cells is T cell dependent , 2021, Science Immunology.
[30] D. Absher,et al. STAT3-mediated allelic imbalance of novel genetic variant rs1047643 and B cell specific super-enhancer in association with systemic lupus erythematosus , 2021, bioRxiv.
[31] J. Holoshitz,et al. The Cusp theory: is there more to HLA-disease association? , 2021, Rheumatology.
[32] Aaron M. Rosenfeld,et al. Altered function and differentiation of age-associated B cells contribute to the female bias in lupus mice , 2021, Nature Communications.
[33] Q. Lu,et al. A novel humanized cutaneous lupus erythematosus mouse model mediated by IL-21-induced age-associated B cells. , 2021, Journal of autoimmunity.
[34] K. Brown,et al. Latent gammaherpesvirus exacerbates arthritis through modification of age-associated B cells , 2021, eLife.
[35] Maxim N. Artyomov,et al. Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders , 2021, Science.
[36] P. Lieberman,et al. Epigenetic Plasticity Enables CNS-Trafficking of EBV-infected B Lymphocytes , 2021, PLoS pathogens.
[37] K. Tarte,et al. Mass Cytometry Identifies Expansion of T-bet+ B Cells and CD206+ Monocytes in Early Multiple Sclerosis , 2021, Frontiers in Immunology.
[38] M. Hertl,et al. Detection of autoreactive CD4+ T cells by MHC class II multimers in HLA-linked human autoimmune diseases. , 2021, The Journal of clinical investigation.
[39] P. Heeringa,et al. B Cell Activation and Escape of Tolerance Checkpoints: Recent Insights from Studying Autoreactive B Cells , 2021, Cells.
[40] B. Becher,et al. Mass Cytometry of CSF Identifies an MS-Associated B-cell Population , 2021, Neurology: Neuroimmunology & Neuroinflammation.
[41] L. Aira,et al. Skin-homing regulatory B cells required for suppression of cutaneous inflammation. , 2021, The Journal of investigative dermatology.
[42] M. Sahraian,et al. Clinical Features of Late-Onset Multiple Sclerosis: a Systematic Review and Meta-analysis. , 2021, Multiple sclerosis and related disorders.
[43] J. Guéry,et al. Escape from X Chromosome Inactivation and the Female Predominance in Autoimmune Diseases , 2021, International journal of molecular sciences.
[44] T. Matsushita,et al. Suppression of IL-23-mediated psoriasis-like inflammation by regulatory B cells , 2021, Scientific Reports.
[45] D. Tenen,et al. Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines. , 2021, Gene.
[46] T. Dörner,et al. Toll-like receptor signalling in B cells during systemic lupus erythematosus , 2020, Nature Reviews Rheumatology.
[47] M. Altfeld,et al. Heterogeneous Escape from X Chromosome Inactivation Results in Sex Differences in Type I IFN Responses at the Single Human pDC Level , 2020, Cell Reports.
[48] S. Brunak,et al. Type I Interferons Promote Germinal Centers Through B Cell Intrinsic Signaling and Dendritic Cell Dependent Th1 and Tfh Cell Lineages , 2020, bioRxiv.
[49] L. Staudt,et al. Rewiring of B cell receptor signaling by Epstein–Barr virus LMP2A , 2020, Proceedings of the National Academy of Sciences.
[50] A. Syvänen,et al. Function of multiple sclerosis-protective HLA class I alleles revealed by genome-wide protein-quantitative trait loci mapping of interferon signalling , 2020, PLoS genetics.
[51] M. V. van Zelm,et al. The association of Epstein‐Barr virus infection with CXCR3+ B‐cell development in multiple sclerosis: impact of immunotherapies , 2020, European journal of immunology.
[52] J. Smolders,et al. Naive B cells in neuromyelitis optica spectrum disorders: impact of steroid use and relapses , 2020, Brain communications.
[53] Irah L. King,et al. Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing , 2020, The Journal of experimental medicine.
[54] J. Smolders,et al. B and T Cells Driving Multiple Sclerosis: Identity, Mechanisms and Potential Triggers , 2020, Frontiers in Immunology.
[55] J. Lünemann,et al. Attenuated immune control of Epstein–Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA‐DR15 , 2020, European journal of immunology.
[56] J. Kaler,et al. The Prevalence of Autoimmune Disorders in Women: A Narrative Review , 2020, Cureus.
[57] Aaron M. Rosenfeld,et al. The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans. , 2020, Immunity.
[58] Daniel E. Miller,et al. Epstein–Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci , 2020, bioRxiv.
[59] M. Cancro. Age-Associated B Cells. , 2020, Annual review of immunology.
[60] G. Stewart,et al. The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis , 2020, Scientific Reports.
[61] Gavin Giovannoni,et al. Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies , 2019, Trends in Molecular Medicine.
[62] C. Syrett,et al. When the balance is broken: X‐linked gene dosage from two X chromosomes and female‐biased autoimmunity , 2019, Journal of leukocyte biology.
[63] Simon C. Potter,et al. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility , 2019, Science.
[64] Huji Xu,et al. Excessive CD11c+Tbet+ B cells promote aberrant TFH differentiation and affinity-based germinal center selection in lupus , 2019, Proceedings of the National Academy of Sciences.
[65] I. Mårtensson,et al. CD21−/low B cells associate with joint damage in rheumatoid arthritis patients , 2019, Scandinavian journal of immunology.
[66] D. Kitamura,et al. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets , 2019, eLife.
[67] H. D. de Vries,et al. Induction of brain‐infiltrating T‐bet–expressing B cells in multiple sclerosis , 2019, Annals of neurology.
[68] Nir Hacohen,et al. The immune cell landscape in kidneys of patients with lupus nephritis , 2019, Nature Immunology.
[69] Christopher D. Scharer,et al. IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation , 2019, bioRxiv.
[70] D. Arnold,et al. Placebo-Controlled Trial of an Oral BTK Inhibitor in Multiple Sclerosis. , 2019, The New England journal of medicine.
[71] E. Meffre,et al. Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production. , 2019, Brain : a journal of neurology.
[72] G. Stewart,et al. Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility , 2019, Genome medicine.
[73] M. Cancro,et al. T-bet+ B cells: A common denominator in protective and autoreactive antibody responses? , 2019, Current opinion in immunology.
[74] L. Looger,et al. Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians , 2019, PLoS genetics.
[75] M. Cancro,et al. T‐bet+ memory B cells: Generation, function, and fate , 2019, Immunological reviews.
[76] Shiliang Ma,et al. B Cell Dysfunction Associated With Aging and Autoimmune Diseases , 2019, Front. Immunol..
[77] O. Silvennoinen,et al. Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases , 2019, BioDrugs.
[78] M. Khademi,et al. B cell alterations during BAFF inhibition with belimumab in SLE , 2018, EBioMedicine.
[79] J. Gudjonsson,et al. Sex bias in autoimmunity , 2018, Current opinion in rheumatology.
[80] Xuetao Cao,et al. Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response , 2018, Cell.
[81] Huixia Wu,et al. The risk of systemic lupus erythematosus associated with Epstein–Barr virus infection: a systematic review and meta-analysis , 2018, Clinical and Experimental Medicine.
[82] Vaishali R. Moulton. Sex Hormones in Acquired Immunity and Autoimmune Disease , 2018, Front. Immunol..
[83] G. Gibson,et al. Distinct Effector B Cells Induced by Unregulated Toll‐like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus , 2018, Immunity.
[84] Radleigh G. Santos,et al. Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis , 2018, Cell.
[85] Cameron S. Osborne,et al. Enhancer control of miR-155 expression in Epstein-Barr virus infected B cells , 2018, bioRxiv.
[86] Y. Kawasawa,et al. B-Cell-Intrinsic Type 1 Interferon Signaling Is Crucial for Loss of Tolerance and the Development of Autoreactive B Cells , 2018, Cell reports.
[87] D. Al-Sadeq,et al. Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update , 2018, Front. Oncol..
[88] S. Rahman,et al. IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE , 2018, Nature Communications.
[89] A. Bar-Or,et al. Effect of ocrelizumab on vaccine responses in patients with multiple sclerosis , 2018, Neurology.
[90] M. Rovaris,et al. HLA alleles modulate EBV viral load in multiple sclerosis , 2018, Journal of Translational Medicine.
[91] R. Jessberger,et al. Regulation of Age-associated B cells by IRF5 in systemic autoimmunity , 2018, Nature Immunology.
[92] Daniel E. Miller,et al. Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity , 2018, Nature Genetics.
[93] A. Canivet,et al. TLR7 escapes X chromosome inactivation in immune cells , 2018, Science Immunology.
[94] M. Ban,et al. Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells , 2018, Brain : a journal of neurology.
[95] E. A. Mills,et al. Next-generation anti-CD20 monoclonal antibodies in autoimmune disease treatment , 2017, Autoimmunity Highlights.
[96] K. Tarte,et al. IL-2 imprints human naive B cell fate towards plasma cell through ERK/ELK1-mediated BACH2 repression , 2017, Nature Communications.
[97] P. Marrack,et al. T-bet expressing B cells - Novel target for autoimmune therapies? , 2017, Cellular immunology.
[98] E. Kieff,et al. The Epstein-Barr Virus Regulome in Lymphoblastoid Cells. , 2017, Cell host & microbe.
[99] Lingling Wu,et al. T-bet+CD11c+ B cells are critical for antichromatin immunoglobulin G production in the development of lupus , 2017, Arthritis Research & Therapy.
[100] Marjolein J. W. de Bruijn,et al. Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease , 2017, Arthritis & rheumatology.
[101] H. Eibel,et al. High SYK Expression Drives Constitutive Activation of CD21low B Cells , 2017, The Journal of Immunology.
[102] P. Marrack,et al. B cells expressing the transcription factor T-bet drive lupus-like autoimmunity , 2017, The Journal of clinical investigation.
[103] M. Cancro,et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens , 2017, The Journal of clinical investigation.
[104] Cisca Wijmenga,et al. The MHC locus and genetic susceptibility to autoimmune and infectious diseases , 2017, Genome Biology.
[105] Joseph H. Marcus,et al. Overexpression of the Cytokine BAFF and Autoimmunity Risk , 2017, The New England journal of medicine.
[106] M. Ostrowski,et al. T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response. , 2017, JCI insight.
[107] X. Zuo,et al. A genome-wide association study identifies six novel risk loci for primary biliary cholangitis , 2022 .
[108] C. Mackay,et al. c-Myb Regulates the T-Bet-Dependent Differentiation Program in B Cells to Coordinate Antibody Responses. , 2017, Cell reports.
[109] Genita Metzler,et al. Altered B cell signalling in autoimmunity , 2017, Nature Reviews Immunology.
[110] T. Kurosaki,et al. The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help , 2017, The Journal of experimental medicine.
[111] D. M. van der Heijde,et al. Baricitinib versus Placebo or Adalimumab in Rheumatoid Arthritis , 2017, The New England journal of medicine.
[112] Bernhard Hemmer,et al. Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis , 2017, The New England journal of medicine.
[113] J. Tobias,et al. Age-Associated B Cells Express a Diverse Repertoire of VH and Vκ Genes with Somatic Hypermutation , 2017, The Journal of Immunology.
[114] E. Kieff,et al. Epstein–Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation , 2016, Proceedings of the National Academy of Sciences.
[115] N. Hellings,et al. Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients , 2016, The Journal of Immunology.
[116] WangJinjing,et al. T-bet-Expressing B Cells Are Positively Associated with Crohn's Disease Activity and Support Th1 Inflammation , 2016 .
[117] Fredrick R. Schumacher,et al. Modeling disease risk through analysis of physical interactions between genetic variants within chromatin regulatory circuitry , 2016, Nature Genetics.
[118] E. Wherry,et al. Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells , 2016, The Journal of Immunology.
[119] E. Meffre,et al. PTPN22 inhibition resets defective human central B cell tolerance , 2016, Science Immunology.
[120] M. V. van Zelm,et al. B-Cell Dysregulation in Crohn's Disease Is Partially Restored with Infliximab Therapy , 2016, PloS one.
[121] T. Kurosaki,et al. Regulated selection of germinal-center cells into the memory B cell compartment , 2016, Nature Immunology.
[122] M. Shlomchik,et al. Continuous inhibitory signaling by both SHP-1 and SHIP-1 pathways is required to maintain unresponsiveness of anergic B cells , 2016, The Journal of experimental medicine.
[123] D. Rawlings,et al. B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6 , 2016, The Journal of experimental medicine.
[124] F. Borrego,et al. Fc Receptor–like 5 Expression Distinguishes Two Distinct Subsets of Human Circulating Tissue–like Memory B Cells , 2016, The Journal of Immunology.
[125] Y. Kochi. Genetics of autoimmune diseases: perspectives from genome-wide association studies. , 2016, International immunology.
[126] M. Atchison,et al. Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X , 2016, Proceedings of the National Academy of Sciences.
[127] Kyoung-Jae Won,et al. EBNA2 Drives Formation of New Chromosome Binding Sites and Target Genes for B-Cell Master Regulatory Transcription Factors RBP-jκ and EBF1 , 2016, PLoS pathogens.
[128] M. Shlomchik,et al. Requirement for Transcription Factor Ets1 in B Cell Tolerance to Self-Antigens , 2015, The Journal of Immunology.
[129] Ivan V. Gregoretti,et al. Diversity, cellular origin and autoreactivity of antibody-secreting cell expansions in acute Systemic Lupus Erythematosus , 2015, Nature Immunology.
[130] P. Marrack,et al. TLR7, IFNγ, and T-bet: their roles in the development of ABCs in female-biased autoimmunity. , 2015, Cellular immunology.
[131] A. Betz,et al. The Novel Kinase Inhibitor PRT062070 (Cerdulatinib) Demonstrates Efficacy in Models of Autoimmunity and B-Cell Cancer , 2014, The Journal of Pharmacology and Experimental Therapeutics.
[132] P. Lipsky,et al. Increased Frequency of a Unique Spleen Tyrosine Kinase Bright Memory B Cell Population in Systemic Lupus Erythematosus , 2014, Arthritis & rheumatology.
[133] M. Daly,et al. Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants , 2014, Nature.
[134] L. Hutt-Fletcher,et al. Epstein-Barr Virus Glycoprotein gB and gHgL Can Mediate Fusion and Entry in trans, and Heat Can Act as a Partial Surrogate for gHgL and Trigger a Conformational Change in gB , 2014, Journal of Virology.
[135] Z. Zhou,et al. Assembly and Architecture of the EBV B Cell Entry Triggering Complex , 2014, PLoS pathogens.
[136] P. Mccombe,et al. Gender differences in autoimmune disease , 2014, Frontiers in Neuroendocrinology.
[137] A. Satterthwaite,et al. A Balance between B Cell Receptor and Inhibitory Receptor Signaling Controls Plasma Cell Differentiation by Maintaining Optimal Ets1 Levels , 2014, The Journal of Immunology.
[138] P. Gaffney,et al. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. , 2014, American journal of human genetics.
[139] S. Tangye,et al. Cytokine-Mediated Regulation of Plasma Cell Generation: IL-21 Takes Center Stage , 2014, Front. Immunol..
[140] J. Casanova,et al. IL-21 signalling via STAT3 primes human naive B cells to respond to IL-2 to enhance their differentiation into plasmablasts. , 2013, Blood.
[141] J. Casanova,et al. Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells , 2013, The Journal of experimental medicine.
[142] M. Carrington,et al. Fine-Mapping the Genetic Association of the Major Histocompatibility Complex in Multiple Sclerosis: HLA and Non-HLA Effects , 2013, PLoS genetics.
[143] L. Hurst,et al. Genes That Escape X-Inactivation in Humans Have High Intraspecific Variability in Expression, Are Associated with Mental Impairment but Are Not Slow Evolving , 2013, Molecular biology and evolution.
[144] P. Marrack,et al. T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance , 2013, Proceedings of the National Academy of Sciences.
[145] L. Davis,et al. SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature , 2013, PloS one.
[146] D. Hafler,et al. Specific peripheral B cell tolerance defects in patients with multiple sclerosis. , 2013, The Journal of clinical investigation.
[147] R. Moon,et al. A disease-associated PTPN22 variant promotes systemic autoimmunity in murine models. , 2013, The Journal of clinical investigation.
[148] J. Cambier. Autoimmunity risk alleles: hotspots in B cell regulatory signaling pathways. , 2013, The Journal of clinical investigation.
[149] D. Cantrell,et al. The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway , 2013, Immunity.
[150] P. Marrack,et al. TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice , 2012, Immunologic Research.
[151] Toshihide Kobayashi,et al. Role for Phospholipid Flippase Complex of ATP8A1 and CDC50A Proteins in Cell Migration* , 2012, The Journal of Biological Chemistry.
[152] E. Coccia,et al. Epstein–Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis , 2012, Annals of the rheumatic diseases.
[153] J. Lünemann,et al. Persistence of Epstein-Barr Virus in Self-Reactive Memory B Cells , 2012, Journal of Virology.
[154] B. Arnulf,et al. The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells. , 2012, Blood.
[155] G. Nienhaus,et al. Human B cells differentiate into granzyme B‐secreting cytotoxic B lymphocytes upon incomplete T‐cell help , 2012, Immunology and cell biology.
[156] L. Criswell,et al. Emerging patterns of genetic overlap across autoimmune disorders , 2012, Genome Medicine.
[157] Robert M. Plenge,et al. Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis , 2011, Nature Genetics.
[158] H. Lassmann,et al. Epstein–Barr virus in the multiple sclerosis brain: a controversial issue—report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria , 2011, Brain : a journal of neurology.
[159] P. Marrack,et al. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity. , 2011, Blood.
[160] Kasper Lage,et al. Pervasive Sharing of Genetic Effects in Autoimmune Disease , 2011, PLoS genetics.
[161] A. Davidson,et al. BAFF and selection of autoreactive B cells. , 2011, Trends in immunology.
[162] K. Peterson,et al. TLR7 and TLR9 trigger distinct neuroinflammatory responses in the CNS. , 2011, The American journal of pathology.
[163] D. Iliopoulos,et al. Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression , 2011, Annals of the rheumatic diseases.
[164] Kenneth M. Murphy,et al. Batf controls the global regulators of class switch recombination in both B and T cells , 2011, Nature Immunology.
[165] M. Tardieu,et al. Interferon-Alpha Triggers B Cell Effector 1 (Be1) Commitment , 2011, PloS one.
[166] Yonggang Sha,et al. B Cells as a Therapeutic Target for IFN-β in Relapsing–Remitting Multiple Sclerosis , 2011, The Journal of Immunology.
[167] M. Cancro,et al. A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice. , 2011, Blood.
[168] N. Raab-Traub,et al. Epstein-Barr Virus LMP1 Activates EGFR, STAT3, and ERK through Effects on PKCδ , 2011, Journal of Virology.
[169] Charles Peterfy,et al. An oral Syk kinase inhibitor in the treatment of rheumatoid arthritis: a three-month randomized, placebo-controlled, phase II study in patients with active rheumatoid arthritis that did not respond to biologic agents. , 2011, Arthritis and rheumatism.
[170] M. Genovese,et al. An oral spleen tyrosine kinase (Syk) inhibitor for rheumatoid arthritis. , 2010, The New England journal of medicine.
[171] M. Colonna,et al. Type I IFN enhances follicular B cell contribution to the T cell–independent antibody response , 2010, The Journal of experimental medicine.
[172] A. Ascherio,et al. Primary infection with the Epstein‐Barr virus and risk of multiple sclerosis , 2010, Annals of neurology.
[173] Philippa Marrack,et al. Genetic and hormonal factors in female-biased autoimmunity. , 2010, Autoimmunity reviews.
[174] Ryan M. O’Connell,et al. Inositol phosphatase SHIP1 is a primary target of miR-155 , 2009, Proceedings of the National Academy of Sciences.
[175] P. Gaffney,et al. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. , 2009, Arthritis and rheumatism.
[176] Michael R. Johnson,et al. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. , 2009, Human molecular genetics.
[177] M. Cancro,et al. BAFF and the plasticity of peripheral B cell tolerance. , 2008, Current opinion in immunology.
[178] K. Rajewsky,et al. LMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switch recombination to IgG1. , 2008, Blood.
[179] J. Minárovits,et al. Regulation and dysregulation of Epstein–Barr virus latency: Implications for the development of autoimmune diseases , 2008, Autoimmunity.
[180] R. Reynolds,et al. Dysregulated Epstein-Barr virus infection in the multiple sclerosis brain , 2007, The Journal of experimental medicine.
[181] Feifei Zhao,et al. Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor. , 2007, Clinical immunology.
[182] C. Cunningham-Rundles,et al. CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance , 2007, The Journal of experimental medicine.
[183] J. Mrázek,et al. Epstein-Barr Virus-Encoded Latent Membrane Protein 1 (LMP1) Induces the Expression of the Cellular MicroRNA miR-146a , 2007, RNA biology.
[184] R. Hardy,et al. Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b. , 2007, Immunity.
[185] R. Straub,et al. Estrogens and Autoimmune Diseases , 2006, Annals of the New York Academy of Sciences.
[186] A. Ascherio,et al. Infectious mononucleosis and risk for multiple sclerosis: A meta‐analysis , 2006, Annals of neurology.
[187] H. Eibel,et al. A new CD21low B cell population in the peripheral blood of patients with SLE. , 2004, Clinical immunology.
[188] P. Emery,et al. Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. , 2004, The New England journal of medicine.
[189] S. Pierce,et al. Cbl-b Negatively Regulates B Cell Antigen Receptor Signaling in Mature B Cells through Ubiquitination of the Tyrosine Kinase Syk , 2003, The Journal of experimental medicine.
[190] Nathalie Balandraud,et al. Epstein-Barr virus load in the peripheral blood of patients with rheumatoid arthritis: accurate quantification using real-time polymerase chain reaction. , 2003, Arthritis and rheumatism.
[191] L. Young,et al. Epstein-Barr Virus Latent Membrane Protein 1 (LMP1) Activates the Phosphatidylinositol 3-Kinase/Akt Pathway to Promote Cell Survival and Induce Actin Filament Remodeling* , 2003, The Journal of Biological Chemistry.
[192] S. Szabo,et al. T-bet regulates IgG class switching and pathogenic autoantibody production , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[193] R. Longnecker,et al. Epstein-Barr Virus Latent Membrane Protein 2a (Lmp2a) Employs the Slp-65 Signaling Module , 2001, The Journal of experimental medicine.
[194] M. Ueffing,et al. Latent membrane protein 1 of Epstein–Barr virus interacts with JAK3 and activates STAT proteins , 1999, The EMBO journal.
[195] G. Ebers. Interferon β treatment for multiple sclerosis , 1999, The Lancet.
[196] S. Anderson,et al. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals. , 1998, Immunity.
[197] D. Thorley-Lawson,et al. EBV persistence in memory B cells in vivo. , 1998, Immunity.
[198] Qingxue Li,et al. Epstein-Barr Virus Uses Different Complexes of Glycoproteins gH and gL To Infect B Lymphocytes and Epithelial Cells , 1998, Journal of Virology.
[199] J. Harley,et al. An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus. , 1997, The Journal of clinical investigation.
[200] J. Todd,et al. HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus , 1987, Nature.
[201] E. Kieff,et al. Epstein-barr virus gp350/220 binding to the B lymphocyte C3d receptor mediates adsorption, capping, and endocytosis , 1987, Cell.
[202] E. Tan,et al. Seroepidemiological study of relationships between Epstein-Barr virus and rheumatoid arthritis. , 1981, The Journal of clinical investigation.
[203] T. Kanda. EBV-Encoded Latent Genes. , 2018, Advances in experimental medicine and biology.
[204] J. Holoshitz,et al. MHC molecules in health and disease: At the cusp of a paradigm shift. , 2011, Self/nonself.
[205] I. Sanz,et al. Altered B cell receptor signaling in human systemic lupus erythematosus. , 2009, Autoimmunity reviews.
[206] A. Zhernakova,et al. Detecting shared pathogenesis from the shared genetics of immune-related diseases , 2009, Nature Reviews Genetics.
[207] R. Reynolds,et al. Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology. , 2007, Brain : a journal of neurology.
[208] S. Ness,et al. Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism. , 1998, Molecular cell.