Cystatin C and Cardiovascular Disease

BACKGROUND Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of creatinine-based

[1]  L. Wilkins Comparison of Heritability of Cystatin C- and Creatinine-Based Estimates of Kidney Function and Their Relation to Heritability of Cardiovascular Disease , 2015, Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease.

[2]  P. Almgren,et al.  Cystatin C Is Not Causally Related to Coronary Artery Disease , 2015, PloS one.

[3]  Ross M. Fraser,et al.  Genetic studies of body mass index yield new insights for obesity biology , 2015, Nature.

[4]  M. Nöthen,et al.  Serum Lipid Levels, Body Mass Index, and Their Role in Coronary Artery Calcification: A Polygenic Analysis , 2015, Circulation: Cardiovascular Genetics.

[5]  P. Magnusson,et al.  Comparison of Heritability of Cystatin C‐ and Creatinine‐Based Estimates of Kidney Function and Their Relation to Heritability of Cardiovascular Disease , 2015, Journal of the American Heart Association.

[6]  S. Burgess Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome , 2014, International journal of epidemiology.

[7]  Tanya M. Teslovich,et al.  Discovery and refinement of loci associated with lipid levels , 2013, Nature Genetics.

[8]  Josef Coresh,et al.  Cystatin C versus creatinine in determining risk based on kidney function. , 2013, The New England journal of medicine.

[9]  W. März,et al.  Cystatin C is independently associated with total and cardiovascular mortality in individuals undergoing coronary angiography. The Ludwigshafen Risk and Cardiovascular Health (LURIC) study. , 2013, Atherosclerosis.

[10]  Ellen T. Gelfand,et al.  The Genotype-Tissue Expression (GTEx) project , 2013, Nature Genetics.

[11]  Tom R. Gaunt,et al.  Loci influencing blood pressure identified using a cardiovascular gene-centric array. , 2013, Human molecular genetics.

[12]  H. Westra,et al.  A Genome-Wide Association Study of Circulating Galectin-3 , 2012, PloS one.

[13]  Simon C. Potter,et al.  Mapping cis- and trans-regulatory effects across multiple tissues in twins , 2012, Nature Genetics.

[14]  Yun Li,et al.  Population-specific coding variant underlies genome-wide association with adiponectin level. , 2012, Human molecular genetics.

[15]  W. Rathmann,et al.  Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque , 2011, Nature Genetics.

[16]  Thomas W. Mühleisen,et al.  Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease , 2011, Nature Genetics.

[17]  Ayellet V. Segrè,et al.  Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis , 2010, Nature Genetics.

[18]  Olli Saarela,et al.  Contribution of 30 Biomarkers to 10-Year Cardiovascular Risk Estimation in 2 Population Cohorts: The MONICA, Risk, Genetics, Archiving, and Monograph (MORGAM) Biomarker Project , 2010, Circulation.

[19]  Eric Boerwinkle,et al.  Association of Genome-Wide Variation With the Risk of Incident Heart Failure in Adults of European and African Ancestry: A Prospective Meta-Analysis From the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium , 2010, Circulation. Cardiovascular genetics.

[20]  Silke Szymczak,et al.  Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility , 2010, PloS one.

[21]  Uwe Völker,et al.  New loci associated with kidney function and chronic kidney disease , 2010, Nature Genetics.

[22]  Tariq Ahmad,et al.  Meta-analysis and imputation refines the association of 15q25 with smoking quantity , 2010, Nature Genetics.

[23]  Mark N. Wass,et al.  Genetic loci influencing kidney function and chronic kidney disease , 2010, Nature Genetics.

[24]  Simon C. Potter,et al.  New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk , 2010, Nature Genetics.

[25]  Ming D. Li,et al.  Genome-wide meta-analyses identify multiple loci associated with smoking behavior , 2010, Nature Genetics.

[26]  O. Wagner,et al.  Cystatin C and the Risk for Cardiovascular Events in Patients With Asymptomatic Carotid Atherosclerosis , 2010, Stroke.

[27]  M. Pencina,et al.  Novel and conventional biomarkers for prediction of incident cardiovascular events in the community. , 2009, JAMA.

[28]  Yurii S. Aulchenko,et al.  Multiple loci associated with indices of renal function and chronic kidney disease , 2009, Nature Genetics.

[29]  R. Schnabel,et al.  Cystatin C and cardiovascular mortality in patients with coronary artery disease and normal or mildly reduced kidney function: results from the AtheroGene study. , 2009, European heart journal.

[30]  D. Levy,et al.  Clinical correlates and heritability of cystatin C (from the Framingham Offspring Study). , 2008, The American journal of cardiology.

[31]  John P A Ioannidis,et al.  Interpretation of tests of heterogeneity and bias in meta-analysis. , 2008, Journal of evaluation in clinical practice.

[32]  M. Farkouh,et al.  Serum cystatin C and increased coronary heart disease prevalence in US adults without chronic kidney disease. , 2008, The American journal of cardiology.

[33]  R. Hui,et al.  Cystatin C, Associated With Hemorrhagic and Ischemic Stroke, Is a Strong Predictor of the Risk of Cardiovascular Events and Death in Chinese , 2007, Stroke.

[34]  Qiong Yang,et al.  A genome-wide association for kidney function and endocrine-related traits in the NHLBI's Framingham Heart Study , 2007, BMC Medical Genetics.

[35]  M. Shlipak,et al.  Association of Cystatin C With Mortality, Cardiovascular Events, and Incident Heart Failure Among Persons With Coronary Heart Disease: Data From the Heart and Soul Study , 2006, Circulation.

[36]  D. Siscovick,et al.  Cystatin C and the risk of death and cardiovascular events among elderly persons. , 2005, The New England journal of medicine.

[37]  Gerard Tromp,et al.  Evidence of linkage and association on chromosome 20 for late-onset Alzheimer disease , 2004, Neurogenetics.

[38]  D. Altman,et al.  Measuring inconsistency in meta-analyses , 2003, BMJ : British Medical Journal.

[39]  S. Ebrahim,et al.  'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? , 2003, International journal of epidemiology.

[40]  P. Libby,et al.  Cystatin C deficiency in human atherosclerosis and aortic aneurysms. , 1999, The Journal of clinical investigation.

[41]  D. Croteau-Chonka,et al.  New genetic loci link adipose and insulin biology to body fat distribution , 2015 .

[42]  C. Sudlow,et al.  Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies , 2012, The Lancet Neurology.

[43]  George Davey Smith,et al.  Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology , 2008, Statistics in medicine.

[44]  M. Staufenbiel,et al.  Cystatin C modulates cerebral beta-amyloidosis. , 2007, Nature genetics.

[45]  Juliane,et al.  Edinburgh Research Explorer Common variants at 10 genomic loci influence hemoglobin A(C) levels via glycemic and nonglycemic pathways , 2010 .