GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
暂无分享,去创建一个
Andrew D. Johnson | P. Elliott | C. Sudlow | J. Danesh | R. Marioni | M. Nalls | Sonia Shah | O. Franco | A. Hofman | A. Uitterlinden | C. Carty | A. Reiner | I. Deary | D. Lawlor | T. Lehtimäki | L. Kiemeney | U. Thorsteinsdóttir | K. Stefánsson | E. Boerwinkle | V. Salomaa | S. Yusuf | M. Kanai | Y. Kamatani | Y. Okada | P. Ridker | D. Chasman | S. Ring | C. Lewis | V. Gudnason | E. Schadt | P. Ellinor | R. Sacco | H. Völzke | P. D. de Bakker | Albert Vernon Smith | C. Schmidt | S. Humphries | C. Kooperberg | A. Hingorani | K. Rexrode | A. Zonderman | M. Evans | D. Leys | E. Tai | J. Björkegren | A. Smit | O. Raitakari | A. Dehghan | Qiong Yang | Shih-Jen Hwang | F. Rivadeneira | G. Thorleifsson | B. Psaty | A. Newman | P. Rothwell | R. Huntley | R. Lovering | B. Penninx | P. Whincup | H. Snieder | E. Ingelsson | D. Trégouët | P. Almgren | O. Melander | K. Taylor | J. Rotter | F. Hsu | L. Lind | M. O’Donnell | A. Havulinna | B. Hedblad | Wei-Min Chen | T. Harris | R. Rauramaa | M. Dichgans | P. Amouyel | W. Rosamond | S. Kittner | B. Kissela | Carlos Cruchaga | S. Pulit | C. Langefeld | N. Wareham | K. Rice | Xiaofeng Zhu | S. Hägg | A. Isaacs | S. Gustafsson | A. Hamsten | E. V. van Leeuwen | C. V. van Duijn | S. Grétarsdóttir | T. Pastinen | U. de Faire | M. Scholz | M. Kubo | M. Loeffler | Xiuqing Guo | Robert D. Brown | J. Jukema | C. O’Donnell | C. Tzourio | R. Schmidt | H. Schmidt | J. Wardlaw | A. Teumer | U. Völker | G. Heiss | D. Saleheen | James G. Wilson | J. Bis | X. Jian | J. Kooner | S. Rich | V. Plagnol | J. Howson | P. Joshi | H. Campbell | E. Holliday | L. Launer | James F. Wilson | Julie A. Johnson | S. Heckbert | W. Post | G. Howard | A. DeStefano | T. Mosley | S. Seshadri | E. Grossi | T. Winkler | N. Franceschini | S. Musani | R. Noordam | T. Bartz | S. Tajuddin | I. Nolte | F. Takeuchi | A. Correa | R. de Mutsert | Q. Duan | Jiang He | C. Langenberg | D. Bowden | J. Chambers | N. Kato | P. van der Harst | D. Mook-Kanamori | W. Palmas | A. Morrison | U. Schminke | E. Mannarino | A. Lindgren | P. McArdle | D. O'leary | H. Markus | R. Strawbridge | K. Gertow | B. Sennblad | F. Veglia | D. Baldassarre | E. Tremoli | L. Lyytikäinen | A. Wong | M. Kumari | M. Kivimaki | D. Kuh | D. Sanghera | T. Ninomiya | T. Galesloot | J. Maguire | A. Butterworth | G. Paré | J. Casas | K. Dhana | R. Hardy | J. Hata | M. Kavousi | S. McLachlan | J. Price | M. Dörr | T. Rundek | Hieab H. H. Adams | G. Chauhan | W. Longstreth | M. Sitzer | D. Woo | B. Pasaniuc | S. Debette | M. Walters | S. Lubitz | S. Trompet | S. W. van der Laan | J. Haessler | A. Cox | L. Lange | R. Morris | V. Thijs | L. Holdt | D. Teupser | T. Tatlisumak | S. Engelter | S. Wannamethee | P. Roussos | J. Hopewell | M. Civelek | A. Manichaikul | A. Mishra | A. Rolfs | O. Benavente | N. Rost | H. Ay | J. Rosand | A. Giese | E. Hofer | J. Lee | A. Słowik | D. Strbian | G. Falcone | I. Férnandez-Cadenas | C. Carrera | C. Jern | S. Wassertheil-Smoller | P. Giral | J. Thiery | M. Irvin | J. Deanfield | S. Sakaue | M. Sale | R. Malik | R. Burkhardt | L. Raffield | M. Sargurupremraj | M. Graff | C. Giambartolomei | Q. Wong | C. Finan | M. Ikram | F. Beutner | C. Roselli | M. den Hoed | P. D. de Vries | O. Franzén | K. Wiggins | J. de Graaf | L. Rutten-Jacobs | J. Meschia | C. Wassel | R. Gottesman | J. Halcox | Pankaj Sharma | D. Kleindorfer | R. Grewal | Lingyi Lu | Keith L. Keene | B. Worrall | C. Dale | H. Hyacinth | M. Traylor | S. Bevan | G. Boncoraglio | M. Chong | T. Shah | R. Lemmens | T. Ago | Veronica Codoni | J. Cole | P. Magnusson | J. Engmann | N. Pitkänen | S. Kurl | Y. Saba | C. Fava | A. Ruusalepp | C. Anderson | I. Cotlarciuc | Ahamad Hassan | J. Jiménez‐Conde | Wei-Yu Lin | E. Lorentzen | K. Rannikmäe | B. Sapkota | C. Tanislav | Steffen Tiedt | Simon Koplev | I. Christophersen | Xiaoling Zhang | A. Britton | Pramod Anugu | Jingjing Liang | O. Rueda-Ochoa | Janne Pott | Yukinori Aniket Loes Anne-Katrin Sander W. Solveig Christop Okada Mishra Rutten-Jacobs Giese van der | Nick Smith | A. Seldenrijk | A. Smith | A. Johnson | J. Jimenez-Conde | S. G. Wannamethee | Caroline Dale | J. Jiménez-Conde | Oscar Franzén | S. Gretarsdottir | P. van der harst | Sonia H. Shah | A. Smith | A. Uitterlinden | M. Kubo | A. Hofman | C. V. van Duijn | B. Psaty | A. Newman | A. Destefano | Kristiina Rannikmäe
[1] R. Marioni,et al. DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936 , 2020, Clinical Epigenetics.
[2] Andrew D. Johnson,et al. Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes , 2018, Nature Genetics.
[3] Wen Zhang,et al. A Bayesian Framework for Multiple Trait Colocalization from Summary Association Statistics , 2017, bioRxiv.
[4] G. Schuler,et al. Genome-wide meta-analysis identifies novel loci of plaque burden in carotid artery. , 2017, Atherosclerosis.
[5] John P. Overington,et al. The druggable genome and support for target identification and validation in drug development , 2016, Science Translational Medicine.
[6] K. Hirata,et al. Targeted Disruption of JCAD (Junctional Protein Associated With Coronary Artery Disease)/KIAA1462, a Coronary Artery Disease–Associated Gene Product, Inhibits Angiogenic Processes In Vitro and In Vivo , 2017, Arteriosclerosis, thrombosis, and vascular biology.
[7] Min A. Jhun,et al. Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis , 2016, Circulation. Cardiovascular genetics.
[8] B. Ohlsson,et al. PT05.1: Intake of Different Types of Red Meat, Poultry and Fish and Incident Colorectal Cancer in Women and Men - Results from the Malmö Diet and Cancer Study , 2016 .
[9] Tom Michoel,et al. Cardiometabolic risk loci share downstream cis- and trans-gene regulation across tissues and diseases , 2016, Science.
[10] Mark D. Huffman,et al. Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association , 2016, Circulation.
[11] Yakir A Reshef,et al. Partitioning heritability by functional annotation using genome-wide association summary statistics , 2015, Nature Genetics.
[12] Arno Villringer,et al. The LIFE-Adult-Study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany , 2015, BMC Public Health.
[13] Jean-Francois Mangin,et al. R2* mapping for brain iron: associations with cognition in normal aging , 2015, Neurobiology of Aging.
[14] Michael Q. Zhang,et al. Integrative analysis of 111 reference human epigenomes , 2015, Nature.
[15] M. Biddle,et al. A report from the American Heart Association Council on Cardiovascular and Stroke Nursing. , 2015, The Journal of cardiovascular nursing.
[16] J. Mangin,et al. Magnetization Transfer Ratio Relates to Cognitive Impairment in Normal Elderly , 2014, Front. Aging Neurosci..
[17] Eleazar Eskin,et al. Identifying Causal Variants at Loci with Multiple Signals of Association , 2014, Genetics.
[18] Zoltán Kutalik,et al. Quality control and conduct of genome-wide association meta-analyses , 2014, Nature Protocols.
[19] I. Deary,et al. Vascular risk factors, large-artery atheroma, and brain white matter hyperintensities , 2014, Neurology.
[20] T. Meehan,et al. An atlas of active enhancers across human cell types and tissues , 2014, Nature.
[21] Joseph K. Pickrell. Joint analysis of functional genomic data and genome-wide association studies of 18 human traits , 2013, bioRxiv.
[22] C. Wallace,et al. Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics , 2013, PLoS genetics.
[23] Nick C Fox,et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease , 2013, Nature Genetics.
[24] S. Kardia,et al. Genome-Wide Association Study of Gene by Smoking Interactions in Coronary Artery Calcification , 2013, PloS one.
[25] Sonia Shah,et al. Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis: Mendelian Randomization Analysis , 2013, Circulation. Cardiovascular genetics.
[26] D. Lawlor,et al. Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort , 2012, International journal of epidemiology.
[27] Lihua Julie Zhu,et al. Integrative analysis of ChIP-chip and ChIP-seq dataset. , 2013, Methods in molecular biology.
[28] Sonia Shah,et al. Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk , 2012, Circulation. Cardiovascular genetics.
[29] D. Weiss,et al. The role of lysyl oxidase family members in the stabilization of abdominal aortic aneurysms. , 2012, American journal of physiology. Heart and circulatory physiology.
[30] Data production leads,et al. An integrated encyclopedia of DNA elements in the human genome , 2012 .
[31] J. Marchini,et al. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing , 2012, Nature Genetics.
[32] I. Deary,et al. Brain Aging, Cognition in Youth and Old Age and Vascular Disease in the Lothian Birth Cohort 1936: Rationale, Design and Methodology of the Imaging Protocol* , 2011, International journal of stroke : official journal of the International Stroke Society.
[33] E. Nabel,et al. Genomics of cardiovascular disease. , 2011, The New England journal of medicine.
[34] Donald M Berwick,et al. The "Million Hearts" initiative--preventing heart attacks and strokes. , 2011, The New England journal of medicine.
[35] T. Komori,et al. A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions. , 2011, Biochemical and biophysical research communications.
[36] W. Rathmann,et al. Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque , 2011, Nature Genetics.
[37] P. Visscher,et al. GCTA: a tool for genome-wide complex trait analysis. , 2011, American journal of human genetics.
[38] Joseph,et al. A Comprehensively Examined Sample for Genetic and Epide- miological Studies of Type 2 Diabetes and its Complications , 2011 .
[39] C. Gieger,et al. Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. , 2011, European heart journal.
[40] Mitchell H. Gail,et al. On Combining Data From Genome-Wide Association Studies to Discover Disease-Associated SNPs , 2009, 1010.5046.
[41] P. Donnelly,et al. A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies , 2009, PLoS genetics.
[42] K. Lunetta,et al. Methods in Genetics and Clinical Interpretation Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Design of Prospective Meta-Analyses of Genome-Wide Association Studies From 5 Cohorts , 2010 .
[43] N. Wray,et al. Genomewide Association for Major Depressive Disorder: A possible role for the presynaptic protein Piccolo , 2008, Molecular Psychiatry.
[44] M. Jokela,et al. The Whitehall II Study , 2009 .
[45] Igor Rudan,et al. Runs of homozygosity in European populations. , 2008, American journal of human genetics.
[46] M. McCarthy,et al. Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes , 2008, Nature Genetics.
[47] P. Barberger‐Gateau,et al. Tea Consumption Is Inversely Associated With Carotid Plaques in Women , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[48] B. Team. British Women's Heart and Health Study: Data and study instruments , 2008 .
[49] R. Huupponen,et al. Adulthood : The Cardiovascular Risk in Young Finns Study Risk Factors Identified in Childhood and Decreased Carotid Artery Elasticity in , 2005 .
[50] P. Visscher,et al. The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age 11 to age 70 and beyond , 2007, BMC geriatrics.
[51] U. John,et al. [Mental distress and the use of psychiatric and psychotherapeutic treatments services: results of the Study of Health in Pomerania]. , 2005, Psychiatrische Praxis.
[52] L. Cardon,et al. Linkage disequilibrium in young genetically isolated Dutch population , 2004, European Journal of Human Genetics.
[53] Ian J Deary,et al. The impact of childhood intelligence on later life: following up the Scottish mental surveys of 1932 and 1947. , 2004, Journal of personality and social psychology.
[54] R. Holman,et al. Vascular Factors and Risk of Dementia: Design of the Three-City Study and Baseline Characteristics of the Study Population , 2003, Neuroepidemiology.
[55] H. Steinmetz,et al. C-Reactive Protein and Carotid Intimal Medial Thickness in a Community Population , 2002, Journal of cardiovascular risk.
[56] F. Fazekas,et al. MRI cerebral white matter lesions and paraoxonase PON1 polymorphisms : three-year follow-up of the austrian stroke prevention study. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[57] M. Peyot,et al. Extracellular adenosine induces apoptosis of human arterial smooth muscle cells via A(2b)-purinoceptor. , 2000, Circulation research.
[58] F. Fazekas,et al. Assessment of cerebrovascular risk profiles in healthy persons: definition of research goals and the Austrian Stroke Prevention Study (ASPS). , 1994, Neuroepidemiology.
[59] Mindy Seering,et al. Study protocol. , 1992, Occasional paper.
[60] W. Kannel,et al. An investigation of coronary heart disease in families. The Framingham offspring study. , 1979, American journal of epidemiology.
[61] W. Kannel,et al. The Framingham Study An Epidemiological Approach to Coronary Heart Disease , 1966, Circulation.