A rare of Turner syndrom a cas

Turner Syndrome (TS) is a common chromosomal dis order caused by numerical or structural aberrations of se chromosomes occurring in 1:2, 000 to 1:2,500 liveborn females [1]. 45,X monosomy karyotype accounts fo 50-60% of TS cases. Most mosaicisms karyotypes (a 45,X/46,X,X), and partial 45, X with a second structurall abnormal X chromosome consisting of either two short o two long arms [2, 3]. The clinical manifestations of TS in clude short stature, gonadal dysgenesis resulting from de layed puberty, primary amenorrhea, and infertility [4-6]. TS patients produce autoantibodies due to the abnorma X chromosome, which may lead to autoimmune diseases TS patients also have concurrent diseases, such as hypo thyroidism, renal abnormalities, neurocognitive disorders and congenital/acquired cardiovascular diseases [7, 8]. Th relationship between thyroid and TS has been reported pre viously [9]. It has been suggested that there might be a casual rela tionship between aberrations of the X-chromosome and th risk of autoimmune hypothyroidism. Autoimmune hypo thyroidism is common, with an annual incidence of 3.2% i TS. It is suggested that the thyroid function should b checked regularly in TS patients [10]. The aim of this case report presentation is to describ a mosaic 45,X/46,X,i(X)(q10)/47,X,i(X)(q10),i(X)(q10) 49,X,i(X)(q10),i(X)(q10),i(X)(q10),i(X)(q10) with TS, ac companied by a high incidence of autoimmune hypothy roidism.