Screening for obstructive sleep apnoea based on the electrocardiogram-the computers in cardiology challenge

The authors present a method of screening for obstructive sleep apnoea based on the electrocardiogram (ECG). The algorithm combines information from the ECG-derived respiration (EDR) signal and the RR interval tachogram. Power spectral features from the EDR signal were computed using the discrete harmonic wavelet transform, considering the power at the respiratory frequency and at frequencies below 0.1 Hz. Cycles of tachy/bradycardia (consistent with an arousal from sleep, as would be expected at the end of an episode of apnoea) were identified front the RR interval tachogram. Features were collated into minute-by-minute vectors and passed to a classifier. The algorithm correctly classified 81% of all minutes in the test database, with 29/30 patients correctly identified as apnoea or normal. Visual classification produced 92% correct classification, with all 30 patients correct.

[1]  R. J. Peppin An Introduction to Random Vibrations, Spectral and Wavelet Analysis , 1994 .

[2]  A.,et al.  FAST FOURIER TRANSFORMS FOR NONEQUISPACED DATA * , 2022 .

[3]  L. Johnson,et al.  The orienting reflex during waking and sleeping. , 1967, Electroencephalography and clinical neurophysiology.

[4]  Geoffrey J. McLachlan,et al.  Mixture models : inference and applications to clustering , 1989 .

[5]  J. Samet,et al.  Sleep-disordered Breathing and Hypertension: More Research Is Still Needed , 2000 .

[6]  W. Flemons,et al.  Sleep apnea and cardiac arrhythmias. Is there a relationship? , 1993, The American review of respiratory disease.

[7]  W. Kinnear,et al.  Sleep on the cheap: the role of overnight oximetry in the diagnosis of sleep apnoea hypopnoea syndrome , 1999, Thorax.

[8]  Daniel J Buysse,et al.  Sleep–Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research , 2000 .

[9]  E. Fletcher Hypertension in patients with sleep apnoea, a combined effect? , 2000, Thorax.

[10]  J W Winkelman,et al.  The evoked heart rate response to periodic leg movements of sleep. , 1999, Sleep.

[11]  T. Young,et al.  The occurrence of sleep-disordered breathing among middle-aged adults. , 1993, The New England journal of medicine.

[12]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[13]  L. Findley,et al.  Vigilance and automobile accidents in patients with sleep apnea or narcolepsy. , 1995, Chest.

[14]  M. Hilton,et al.  Validation of British Thoracic Society guidelines for the diagnosis of the sleep apnoea/hypopnoea syndrome: can polysomnography be avoided? , 1995, Thorax.

[15]  J. Stradling,et al.  Arterial blood pressure responses to graded transient arousal from sleep in normal humans. , 1993, Journal of applied physiology.