Parkinson's disease classification using gait characteristics and wavelet-based feature extraction

This paper proposes a method to classify idiopathic PD patients and healthy controls using both the gait characteristics of idiopathic PD patients and wavelet-based feature extraction. Using the characteristics of idiopathic PD patients who shuffle their feet while they are walking, we implemented the following three preprocessing methods: (i) we used the difference between two signals that each represented the sum of eight sensor outputs from one foot; (ii) we used the difference between the maximum and minimum records among the vertical ground reaction force outputs from the eight sensors under the left foot; and (iii) we used method (i) again, but on the signals each obtained from one foot by method (ii). After thus conducting the three preprocessing tasks, we created approximation coefficients and detail coefficients using wavelet transforms (WTs). Then, we extracted 40 features from these coefficients by using statistical approaches, including frequency distributions and their variabilities. Using the 40 features as inputs to the neural network with weighted fuzzy membership functions (NEWFM), we compared the performances of the three abovementioned methods. When idiopathic PD patients and healthy controls were classified using the NEWFM, theaccuracy, specificity, and sensitivity of the results were, respectively, as follows: 74.32%, 81.63%, and 73.77% by method (i); 75.18%, 74.67%, and 75.24% by method (ii); or 77.33%, 65.48%, and 81.10% by method (iii).

[1]  S. Fahn Unified Parkinson's Disease Rating Scale, In : S. Fahn, CD. Marsden, DB. Calne, M. Goldstein, Recent Developments in Parkinson's Disease , 1987 .

[2]  Academisch Proefschrift,et al.  UvA-DARE ( Digital Academic Repository ) Clinimetrics , clinical profile and prognosis in early Parkinson ’ s disease , 2009 .

[3]  Jose Alvarez-Ramirez,et al.  Limb dominance changes in walking evolution explored by asymmetric correlations in gait dynamics , 2010 .

[4]  Sang-Hong Lee,et al.  Minimized Stock Forecasting Features Selection by Automatic Feature Extraction Method , 2009 .

[5]  Sang-Hong Lee,et al.  Extracting Input Features and Fuzzy Rules for Classifying Epilepsy Based on NEWFM , 2009 .

[6]  Sang-Hong Lee,et al.  Forecasting KOSPI based on a neural network with weighted fuzzy membership functions , 2011, Expert Syst. Appl..

[7]  Ki-Hyeon Kwon,et al.  An Optimization of Hashing Mechanism for the DHP Association Rules Mining Algorithm , 2010 .

[8]  Robert E Gross,et al.  Deep brain stimulation for Parkinson's disease: Surgical technique and perioperative management , 2006, Movement disorders : official journal of the Movement Disorder Society.

[9]  Dianhui Wang,et al.  A neuro-fuzzy approach for diagnosis of antibody deficiency syndrome , 2006, Neurocomputing.

[10]  W. Koller,et al.  Falls and Parkinson's disease. , 1989, Clinical neuropharmacology.

[11]  Stéphane Mallat,et al.  Zero-crossings of a wavelet transform , 1991, IEEE Trans. Inf. Theory.

[12]  Sang-Hong Lee,et al.  Features Extraction for Classifying Parkinson's Disease Based on Gait Analysis , 2010 .

[13]  Ray-Yau Wang,et al.  Relationships between gait and dynamic balance in early Parkinson's disease. , 2008, Gait & posture.

[14]  Joon S. Lim,et al.  Finding Features for Real-Time Premature Ventricular Contraction Detection Using a Fuzzy Neural Network System , 2009, IEEE Transactions on Neural Networks.

[15]  Do-Young Kwon,et al.  Comparison of Movement of Rapid Alternating Movements of Hands in Idiopathic Parkinson's Disease Patients and Normal Subjects using Angular Velocity Measurement System , 2010 .

[16]  M Richards,et al.  Interrater reliability of the unified Parkinson's disease rating scale motor examination , 1994, Movement disorders : official journal of the Movement Disorder Society.

[17]  Akihiro Takeuchi,et al.  Analysis of gait variability in Parkinson's disease the relationship between frequency-domain features and the severity of the disease , 2006 .

[18]  Xuemei Huang,et al.  Arm swing magnitude and asymmetry during gait in the early stages of Parkinson's disease. , 2010, Gait & posture.

[19]  Gwang-Moon Eom,et al.  Comparison of the Total Stance Time And the Phase Ratio in Parkinson's Disease Patients And Normal Subjects , 2006 .

[20]  P. Martínez-Martín,et al.  Unified Parkinson's disease rating scale characteristics and structure , 1994, Movement disorders : official journal of the Movement Disorder Society.

[21]  Kara K. Patterson,et al.  Evaluation of gait symmetry after stroke: a comparison of current methods and recommendations for standardization. , 2010, Gait & posture.

[22]  N. Malmurugan,et al.  Neural classification of lung sounds using wavelet coefficients , 2004, Comput. Biol. Medicine.

[23]  M. Morris Movement disorders in people with Parkinson disease: a model for physical therapy. , 2000, Physical therapy.

[24]  Byung Jo Kim,et al.  Dynamic Foot Pressure Measurement in Parkinson's Disease with Foot Scan System , 2007 .

[25]  Gábor Fazekas,et al.  Analysis of finger-tapping movement , 2005, Journal of Neuroscience Methods.