论文信息 - Analgesic effects of quetiapine in two cases

Analgesic effects of quetiapine in two cases

To the Editor, Quetiapine is an atypical antipsychotic, frequently used for bipolar disorder and schizophrenia. Furthermore quetiapine is approved as a combination treatment for major depression. Combining quetiapine with SSRIs or venlafaxine increases drug response and relieves comorbid anxiety and residual depressive symptoms.1 Interestingly there are mounting data, denoting potential analgesic effect of quetiapine. There are several reports pointing out quetiapine relieves pain in fibromyalgia, migraine and chronic regional pain syndrome.2 Here we report two case report who benefited from analgesic effect of quetiapine.

Ebru Fındıklı | M. Camkurt | Serkan Güneş

[1] A. Gendron,et al. Quetiapine Fumarate Extended‐Release for the Treatment of Major Depression With Comorbid Fibromyalgia Syndrome: A Double‐Blind, Randomized, Placebo‐Controlled Study , 2014, Arthritis & rheumatology.

[2] S. Pridmore,et al. Will the Atypical Antipsychotics be Analgesics? , 2003 .

[3] K. Någren,et al. Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity , 2002, PAIN.

[4] A. McIntyre,et al. Quetiapine adjunct to selective serotonin reuptake inhibitors or venlafaxine in patients with major depression, comorbid anxiety, and residual depressive symptoms: a randomized, placebo‐controlled pilot study , 2007, Depression and anxiety.