2022-RA-591-ESGO Twenty years of experience with less radical fertility-sparing surgery in early-stage cervical cancer: pregnancy outcomes

2022-RA-595-ESGO Figure 1 Abstracts Int J Gynecol Cancer 2022;32(Suppl 2):A1–A504 A171 on D ecem er 5, 2022 by gest. P rocted by coright. http/ijgc.bm jcom / nt J G ynecol C acer: frst pulished as 10.11ijgc-2022-E S G O .68 on 20 O cber 222. D ow nladed fom Results The cell population included large consistency of positive cells (A) which were analyzed in their vitality using the PC5-conjugated-7-AAD viability marker. Almost the full population, namely 95.7% of Ddx4 cells were found viable among a minority equal to 4.3% of dead cells (B-C), suggesting that the fragments cryopreservation in liquid nitrogen is almost indolent on the OSC viability. Conclusion The consistency of OSC population from a single cryopreserved ovarian cortex after thawing suggest that this population is apparently resistant to the temperature stress for freezing and thawing, thus reinforcing interest for stemness studies in treatment of female CTRI. 2022-VA-596-ESGO LAPAROSCOPIC VAGINAL RADICAL TRACHELECTOMY IN THE POST LACC ERA: STEP BY STEP SURGICAL PROCEDURE Benedetta Guani, Vincent Balaya, Fabrice Lecuru, Patrice Matehvet. CHUV, Lausanne, Switzerland; HFR, Fribourg, Switzerland; Hopital Foch, suresnes, France; Hopital Curie, Paris, France 10.1136/ijgc-2022-ESGO.369 Introduction/Background Therapeutic management of early stage cervical cancer is mainly based on surgery. Radical trachelectomy is a strategy to preserve the fertility of young patients with cervical cancer. In the ESGO and NCCN Guidelines, Radical Trachelectomy type B is indicated in case of cervical cancer stage 1B1. The prospective CONCERV study shows the safety of the simple conisation in early-stage cervical cancer <2 cm in case of stroll invasion <10 mm and no lymph vascular space invasion.Actually the indication to the radical trachelectomy remains:-Cervical cancer <2 cm-FIGO stage not more 1B1-Negative lymph node-Positive LVSI The oncological safety of the minimally invasive approach has recently questioned by the international randomized LACC trial. This result have therefore renewed interest in the vaginal approach, associated to lymph node staging by laparoscopy. Methodology We described the indication and the procedure in a video. Results In this video we described the radical trachelectomy by the laparoscopic vaginal approach in 10 steps. Abstract 2022-VA-596-ESGO Figure 1 Conclusion This technique is a safe oncological procedure in the post-LACC era.2022-VA-596-ESGO Figure 1 Conclusion This technique is a safe oncological procedure in the post-LACC era. 2022-RA-598-ESGO PROGNOSTIC FACTORS FOR ADVERSE OBSTETRIC OUTCOMES IN PREGNANT CANCER PATIENTS AN UPDATE ON 2174 CASES REGISTERED IN THE INCIP REGISTRY Charlotte Maggen, Joosje Heimovaara, Kristel van Calsteren, Elyce Cardonick, Annouschka Laenen, Roman G Shmakov, Vera Wolters, Mina Mhallem Gziri, Christianne Lok, Evgeniya Polushkina, Jeroen Blommaert, Michael Halaska, Robert Fruscio, Alvaro Cabrera-Garcia, Ingrid A Boere, Ingrid A Boere, Petronella Ottevanger, Giovanna Scarfone, Jorine de Haan, Frédéric Amant. Obstetrics and perinatal medicine, UZ Brussels, Jette, Belgium; KU Leuven, Leuven, Belgium; University Hospitals of Leuven, Leuven, Belgium; Department of Obstetrics and Gynecology, Cooper, University Health Care, Camden, NJ, USA, Camden, NJ; Statistics, KU Leuven, Leuven, Belgium; National Medical Research Centre for Obstetrics, Gynecology and Perinatology named after Academician V.I. Kulakov of the Ministry of Healthcare of Russian Federation, Moscow, Russia, Moscow, Russian Federation; Department of Gynecology, Antoni van Leeuwenhoek – Netherlands Cancer Institute, Amsterdam, The Netherlands, Amsterdam, Netherlands; Department of Obstetrics, Cliniques Universitaires St Luc, UCL, Sint-Lambrechts-Woluwe, Belgium, Sint-Lambrechts-Woluwe, Belgium; Faculty Hospital Kralovske, Vinohrady and 3rd Medical Faculty, Charles University, Prague, Czech Republic, Prague, Czech Republic; Clinic of Obstetrics and Gynecology, University of Milan – Bicocca, San Gerardo Hospital, Monza, Italy, Milan, Italy; Hospital Regional de Alta Especialidad de Ixtapaluca (HRAEI) ‘ Reference clinic for hemato-oncological diseases during pregnancy CREHER’ Estado de México, México, Mexico, Mexico; Department of Medical Oncology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands., Rotterdam, Netherlands; Department of Obstetrics and Gynecology, University of Turin, Città della Salute e della Scienza, Sant’Anna Hospital, via Ventimiglia 1, 10126, Turin, Italy., Turin, Italy; Department of Medical Oncology, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands., Nijmegen, Netherlands; Gynecological Oncology Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Ca’ Granda Ospedale Maggiore Policlinico Milan, Milan, Italy., Milan, Italy; Department of Obstetrics and Gynecology, Amsterdam University Medical Centers, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Amsterdam, Netherlands 10.1136/ijgc-2022-ESGO.370 Introduction/Background Following the increasing evidence on fetal safety, over time more pregnant women are receiving cancer treatment, including chemotherapy, in order to safeguard maternal prognosis. To evaluate current clinical practice obstetric and neonatal outcomes of women registered by the International Network on Cancer, Infertility and Pregnancy (INCIP) were assessed. Abstract 2022-RA-598-ESGO Figure 1 Distribution of cancer types and cancer stages at diagnosis by cancer type (n=2174) Abstracts2022-RA-598-ESGO Figure 1 Distribution of cancer types and cancer stages at diagnosis by cancer type (n=2174) Abstracts A172 Int J Gynecol Cancer 2022;32(Suppl 2):A1–A504 on D ecem er 5, 2022 by gest. P rocted by coright. http/ijgc.bm jcom / nt J G ynecol C acer: frst pulished as 10.11ijgc-2022-E S G O .68 on 20 O cber 222. D ow nladed fom