Effects of Modified Ultrafiltration in Pediatric Cardiac Surgery

当施設で施行された体重15kg以 下の小児根治的開心術86例 について, modined ultrafiltration (MUF) の効果を無輸血症例 (34例) と輸血施行症例 (52例) とに分け検討した. 無輸血症例, 輸血施行症例とも にMUF施 行群は, MUF未 施行群に比べて体外循環終了20分 後 (MUF終 了後) のヘマ トクリット値 と血 清蛋白値を有意に上昇させた. また両群 とも, 左房圧を上昇させずに体外循環終了20分 後の収縮期動脈圧 を上昇させ, 左心機能を改善させた. 輸血施行症例において, MUF施 行群はMUF未 施行群に比べて大動 脈遮断解除6, 12, 24時 間後の肺酸素化能 (PaO2/FiO2) を有意に改善 させ, 輸血量も少ない傾向にあっ た. 小児開心術症例において, 無輸血症例, 輸血症例ともにMUFは 非常に有用な手段と考えられた. 日心 外会誌30巻6号: 290-294 (2001)

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