Evidence that epithelial glycoprotein 330/megalin mediates uptake of polybasic drugs.
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S. Moestrup | H. Vorum | J. Gliemann | K. Norris | C. Bregengård | S. Bjørn | E. I. Christensen | S. Cui | S. Moestrup
[1] T. Hammond,et al. Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules. , 1995, European journal of cell biology.
[2] M. Farquhar,et al. Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene family. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[3] S. Moestrup,et al. Binding and Endocytosis of Proteins Mediated by Epithelial gp330 , 1994, Annals of the New York Academy of Sciences.
[4] A. Schwartz,et al. The low density lipoprotein receptor-related protein mediates the cellular degradation of tissue factor pathway inhibitor. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[5] K. Orth,et al. Molecular dissection of ligand binding sites on the low density lipoprotein receptor-related protein. , 1994, The Journal of biological chemistry.
[6] J. Rastad,et al. A protein involved in calcium sensing of the human parathyroid and placental cytotrophoblast cells belongs to the LDL-receptor protein superfamily. , 1994, Experimental cell research.
[7] S. Moestrup. The alpha 2-macroglobulin receptor and epithelial glycoprotein-330: two giant receptors mediating endocytosis of multiple ligands. , 1994, Biochimica et biophysica acta.
[8] D. Strickland,et al. Immunological localization of glycoprotein 330, low density lipoprotein receptor related protein and 39 kDa receptor associated protein in embryonic mouse tissues. , 1994, In vivo.
[9] I. Stamenkovic,et al. Organ distribution in rats of two members of the low-density lipoprotein receptor gene family, gp330 and LRP/alpha 2MR, and the receptor-associated protein (RAP). , 1994, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[10] M. Krieger,et al. Structures and functions of multiligand lipoprotein receptors: macrophage scavenger receptors and LDL receptor-related protein (LRP). , 1994, Annual review of biochemistry.
[11] S. Makker. Analysis of glomeruli-eluted Gp330 autoantibodies and of Gp330 antigen of Heymann nephritis. , 1993, Journal of immunology.
[12] S. Moestrup,et al. Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes. , 1993, The Journal of biological chemistry.
[13] S. Moestrup,et al. The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein binds lipoprotein lipase and beta-migrating very low density lipoprotein associated with the lipase. , 1993, The Journal of biological chemistry.
[14] M. Waknitz,et al. Lipoprotein lipase induces catabolism of normal triglyceride-rich lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor in vitro. A process facilitated by cell-surface proteoglycans. , 1993, The Journal of biological chemistry.
[15] S. Moestrup,et al. Alpha 2-macroglobulin-proteinase complexes, plasminogen activator inhibitor type-1-plasminogen activator complexes, and receptor-associated protein bind to a region of the alpha 2-macroglobulin receptor containing a cluster of eight complement-type repeats. , 1993, The Journal of biological chemistry.
[16] W. Liao,et al. Polymyxin B complexes with and cationizes low density lipoproteins. The cause of polymyxin B-induced enhancement of endocytotic catabolism of low density lipoproteins. , 1993, Biochemical pharmacology.
[17] B. Molitoris,et al. Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells. , 1993, The American journal of physiology.
[18] M. Farquhar,et al. Identification of a cell line that expresses a cell surface and a soluble form of the gp330/receptor-associated protein (RAP) Heymann nephritis antigenic complex. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[19] M. Brown,et al. Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. , 1992, The Journal of biological chemistry.
[20] D. Strickland,et al. The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330. , 1992, The Journal of biological chemistry.
[21] S. Moestrup,et al. Renal tubule gp330 is a calcium binding receptor for endocytic uptake of protein. , 1992, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[22] D. Kerjaschki,et al. gp330 associates with a 44-kDa protein in the rat kidney to form the Heymann nephritis antigenic complex. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[23] S. Moestrup,et al. Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes. , 1992, The Journal of biological chemistry.
[24] D. Strickland,et al. A novel mechanism for controlling the activity of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Multiple regulatory sites for 39-kDa receptor-associated protein. , 1992, The Journal of biological chemistry.
[25] W. Liao,et al. Polymyxin B enhances low density lipoprotein catabolism in hepatic and extrahepatic cells. , 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.
[26] J. Kanalas,et al. Identification of the rat Heymann nephritis autoantigen (GP330) as a receptor site for plasminogen. , 1991, The Journal of biological chemistry.
[27] J. Veldman,et al. Ultrastructural localization of gentamicin in the cochlea , 1990, Hearing Research.
[28] M. Costlow,et al. Binding of polymyxin B to rat alveolar macrophages. , 1990, The Journal of infectious diseases.
[29] S. Moestrup,et al. The human alpha 2-macroglobulin receptor contains high affinity calcium binding sites important for receptor conformation and ligand recognition. , 1990, Journal of Biological Chemistry.
[30] K. Norris,et al. Aprotinin and aprotinin analogues expressed in yeast. , 1990, Biological chemistry Hoppe-Seyler.
[31] R. Raychowdhury,et al. Autoimmune target in Heymann nephritis is a glycoprotein with homology to the LDL receptor. , 1989, Science.
[32] J. Schacht,et al. Kinetics of gentamicin uptake and release in the rat. Comparison of inner ear tissues and fluids with other organs. , 1986, The Journal of clinical investigation.
[33] W. Bennett,et al. Chronic gentamicin nephrotoxicity. Continued tubular injury with preserved glomerular filtration function. , 1986, The American journal of pathology.
[34] P. Verroust,et al. Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. II. Extrarenal distribution. , 1986, The American journal of pathology.
[35] J. Gliemann,et al. Characterization of receptors for α2-macroglobulin-trypsin complex in rat hepatocytes , 1986 .
[36] K. Kenyon,et al. Retinal toxicity of intravitreal gentamicin. An electron microscopic study. , 1984, Investigative ophthalmology & visual science.
[37] Ashutosh Kumar Singh,et al. Characterization of the antigen (gp600) of Heymann nephritis. , 1984, Laboratory investigation; a journal of technical methods and pathology.
[38] J. Weinberg,et al. Calcium is a competitive inhibitor of gentamicin-renal membrane binding interactions and dietary calcium supplementation protects against gentamicin nephrotoxicity. , 1984, The Journal of clinical investigation.
[39] H. Rennke,et al. Renal tubular uptake of protein: effect of molecular charge. , 1983, The American journal of physiology.
[40] V. Batuman,et al. Transport of gentamicin in rat proximal tubule. , 1983, Laboratory investigation; a journal of technical methods and pathology.
[41] D. Kerjaschki,et al. The pathogenic antigen of Heymann nephritis is a membrane glycoprotein of the renal proximal tubule brush border. , 1982, Proceedings of the National Academy of Sciences of the United States of America.
[42] J. Weinberg,et al. Identification of the aminoglycoside binding site in rat renal brush border membranes. , 1982, The Journal of pharmacology and experimental therapeutics.
[43] C. Jacobsen,et al. Determination of reserve albumin-equivalent for ligand binding, probing two distinct binding functions of the protein. , 1982, Analytical biochemistry.
[44] H. Rennke,et al. Effect of molecular charge on endocytic uptake of ferritin in renal proximal tubule cells. , 1981, Laboratory investigation; a journal of technical methods and pathology.
[45] P. Tulkens,et al. Gentamicin-induced nephrotoxicity: a cell biology approach. , 1980, Kidney international.
[46] F. van Leuven,et al. Demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines. , 1979, The Journal of biological chemistry.
[47] P. Tulkens,et al. Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Quantitative ultrastructural and biochemical study. , 1979, Laboratory investigation; a journal of technical methods and pathology.
[48] F. Silverblatt,et al. Autoradiography of gentamicin uptake by the rat proximal tubule cell. , 1979, Kidney international.
[49] D. Morrison,et al. Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. , 1976, Immunochemistry.
[50] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.
[51] D. Houghton,et al. A light and electron microscopic analysis of gentamicin nephrotoxicity in rats. , 1976, The American journal of pathology.
[52] T. Creighton,et al. The two-disulphide intermediates and the folding pathway of reduced pancreatic trypsin inhibitor. , 1975, Journal of molecular biology.