Elimination of synapses in the developing nervous system.

Reduction of the number of axons that contact target cells may be a general feature of neural development. This process may underlie the progressively restricted malleability of the maturing nervous system.

[1]  D. Hubel,et al.  RECEPTIVE FIELDS OF CELLS IN STRIATE CORTEX OF VERY YOUNG, VISUALLY INEXPERIENCED KITTENS. , 1963, Journal of neurophysiology.

[2]  D. Hubel,et al.  SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE. , 1963, Journal of neurophysiology.

[3]  D. Hubel,et al.  Extent of recovery from the effects of visual deprivation in kittens. , 1965, Journal of neurophysiology.

[4]  D. Hubel,et al.  Binocular interaction in striate cortex of kittens reared with artificial squint. , 1965, Journal of neurophysiology.

[5]  D. Hubel,et al.  Comparison of the effects of unilateral and bilateral eye closure on cortical unit responses in kittens. , 1965, Journal of neurophysiology.

[6]  Bo Nystroum POSTNATAL DEVELOPMENT OF MOTOR NERVE TERMINALS IN “SLOW‐RED” AND “FAST‐WHITE” CAT MUSCLES , 1968 .

[7]  B. Katz,et al.  Visual identification of synaptic boutons on living ganglion cells and of varicosities in postganglionic axons in the heart of the frog , 1971, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[8]  S. W. Kuffler,et al.  Synaptic transmission and its duplication by focally applied acetylcholine in parasympathetic neurons in the heart of the frog , 1971, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[9]  I. Black,et al.  Trans-synaptic regulation of growth and development of adrenergic neurones in a mouse sympathetic ganglion. , 1971, Brain research.

[10]  H. Thoenen,et al.  Time course of the development of enzymes involved in the synthesis of norepinephrine in the superior cervical ganglion of the rat from birth to adult life. , 1972, Brain research.

[11]  G. Stent A physiological mechanism for Hebb's postulate of learning. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[12]  J. Changeux,et al.  A theory of the epigenesis of neuronal networks by selective stabilization of synapses. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[13]  J. E. Vaughn,et al.  A morphological investigation of an early reflex pathway in developing rat spinal cord , 1973, The Journal of comparative neurology.

[14]  M. Letinsky The development of nerve-muscle junctions in Rana catesbeiana tadpoles. , 1974, Developmental biology.

[15]  Prestige Mc Axon and cell numbers in the developing nervous system. , 1974 .

[16]  L. Ronnevi,et al.  Ultrastructural evidence for spontaneous elimination of synaptic terminals on spinal motoneurons in the kitten. , 1974, Brain research.

[17]  B. Cragg,et al.  The development of synapses in the visual system of the cat , 1975, The Journal of comparative neurology.

[18]  J. Changeux,et al.  Consequences of tenotomy on the evolution of multiineervation in developing rat soleus muscle , 1975, Brain Research.

[19]  D. Hubel,et al.  Functional architecture of area 17 in normal and monocularly deprived macaque monkeys. , 1976, Cold Spring Harbor symposia on quantitative biology.

[20]  D. Riley Multiple axon branches innervating single endplates of kitten soleus myofibers , 1976, Brain Research.

[21]  R. Levi‐montalcini The nerve growth factor: its role in growth, differentiation and function of the sympathetic adrenergic neuron. , 1976, Progress in brain research.

[22]  J. Jansen,et al.  Morphological aspects of the elimination of polyneuronal innervation of skeletal muscle fibres in newborn rats , 1976, Journal of neurocytology.

[23]  P. Rakic Prenatal genesis of connections subserving ocular dominance in the rhesus monkey , 1976, Nature.

[24]  J. Changeux,et al.  Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks , 1976, Nature.

[25]  F. Crépel,et al.  Evidence for a multiple innervation of Purkinje cells by climbing fibers in the immature rat cerebellum. , 1976, Journal of neurobiology.

[26]  E. Shooter,et al.  Nerve growth factor (third of three parts). , 1977 .

[27]  D. Riley Spontaneous elimination of nerve terminals from the endplates of developing skeletal myofibers , 1977, Brain Research.

[28]  E. Shooter,et al.  Nerve growth factor (third of three parts). , 1977, The New England journal of medicine.

[29]  Ronnevi L-O Spontaneous phagocytosis of boutons on spinal motoneurons during early postnatal development. An electron microscopical study in the cat , 1977 .

[30]  E. Shooter,et al.  Nerve growth factor (second of three parts). , 1977, The New England journal of medicine.

[31]  L. Ronnevi,et al.  Ultrastructure and synaptology of the initial axon segment of cat spinal motoneurons during early postnatal development , 1977, Journal of neurocytology.

[32]  J. Jansen,et al.  The elimination of synapses in multiply-innervated skeletal muscle fibres of the rat: dependence on distance between end-plates , 1977, Brain Research.

[33]  D. K. Berg,et al.  Dissociated ciliary ganglion neurons in vitro: survival and synapse formation. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[34]  P. Rakić Prenatal development of the visual system in rhesus monkey. , 1977, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[35]  D. Hubel,et al.  Plasticity of ocular dominance columns in monkey striate cortex. , 1977, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[36]  J. Jansen,et al.  The extent of sprouting of remaining motor units in partly denervated immature and adult rat soleus muscle , 1977, Neuroscience.

[37]  Gerta Vrbová,et al.  The role of muscle activity in the differentiation of neuromuscular junctions in slow and fast chick muscles , 1978, Journal of neurocytology.

[38]  I. Black,et al.  Regulation of autonomic development. , 1978, Annual review of neuroscience.

[39]  D. Riley,et al.  Tenotomy delays the postnatal development of the motor innervation of the rat soleus , 1978, Brain Research.

[40]  J. Jansen,et al.  The formation and maintenance of synaptic connections as illustrated by studies of the neuromuscular junction. , 1978, Progress in brain research.

[41]  S. Levay,et al.  Ocular dominance columns and their development in layer IV of the cat's visual cortex: A quantitative study , 1978, The Journal of comparative neurology.

[42]  J. Changeux,et al.  Consequences of blocking the nerve with a local anaesthetic on the evolution of multiinnervation at the regenerating neuromuscular junction of the rat , 1978, Brain Research.

[43]  R. Oppenheim,et al.  Neuronal cell death in the brachial spinal cord of the chick is unrelated to the loss of polyneuronal innervation in wing muscle , 1978, Brain Research.

[44]  D. Purves,et al.  Formation and maintenance of synaptic connections in autonomic ganglia. , 1978, Physiological reviews.

[45]  I. Hendry,et al.  Parasympathetic neuronal survival induced by factors from muscle , 1978, Neuroscience Letters.

[46]  J. K. S. Jansen,et al.  The effect of prolonged, reversible block of nerve impulses on the elimination of polyneuronal innervation of new-born rat skeletal muscle fibers , 1979, Neuroscience.

[47]  J. Pettigrew,et al.  Degree of interocular synchrony required for maintenance of binocularity in kitten's visual cortex. , 1979, Journal of neurophysiology.

[48]  M. Bennett,et al.  The survival and development of cholinergic neurons in skeletal muscle conditioned media , 1979, Brain Research.

[49]  D. V. Essen,et al.  Regional differences in the timing of synapse elimination in skeletal muscles of the neonatal rabbit , 1979, Brain Research.

[50]  D. K. Berg,et al.  Survival and development of ciliary ganglion neurones grown alone in cell culture , 1979, Nature.

[51]  F. Vyskocil,et al.  The elimination of polyneuronal innervation of end-plates in developing rat muscles with altered function. , 1979, Progress in brain research.

[52]  G. Raisman,et al.  Synapse formation in the rat superior cervical ganglion during normal development and after neonatal deafferentation , 1980, Brain Research.

[53]  A. Lamb Motoneurone counts in Xenopus frogs reared with one bilaterally-innervated hindlimb , 1980, Nature.

[54]  K. Obata,et al.  Conditioned medium promotes neurite growth from both central and peripheral neurons , 1980, Neuroscience Letters.