DNA breaks generated by the bleomycin-iron III complex in the presence of KHSO5, a single oxygen donor.

[1]  J. Stubbe,et al.  Mechanism of bleomycin: evidence for 4'-ketone formation in poly(dA-dU) associated exclusively with free base release. , 1985, Biochemistry.

[2]  J. Stubbe,et al.  Mechanism of bleomycin: evidence for a rate-determining 4'-hydrogen abstraction from poly(dA-dU) associated with the formation of both free base and base propenal. , 1985, Biochemistry.

[3]  N. Murugesan,et al.  Analysis of products formed during bleomycin-mediated DNA degradation. , 1985, Biochemistry.

[4]  Y. Sugiura,et al.  Copper-bleomycin has no significant DNA cleavage activity. , 1985, Biochemistry.

[5]  N. Murugesan,et al.  Structure of the alkali-labile product formed during iron(II)-bleomycin-mediated DNA strand scission , 1985 .

[6]  N. Murugesan,et al.  Bleomycin as an oxene transferase. Catalytic oxygen transfer to olefins , 1985 .

[7]  R. Moriarty,et al.  Possible role of Lewis acid catalysis in the oxidation of alkenes and α,β-unsaturated ketones using bleomycin-zn(ii) and bleomycin-fe(iii)-iodosylbenzene in aqueous methanol , 1985 .

[8]  B. Meunier,et al.  Oxone as oxygen donor in the catalytic hydroxylation of saturated hydrocarbons , 1985 .

[9]  J. Stubbe,et al.  The mechanism of free base formation from DNA by bleomycin. A proposal based on site specific tritium release from Poly(dA.dU). , 1983, The Journal of biological chemistry.

[10]  O. Bortolini,et al.  Isolation of a high-valent ‘oxo-like’ manganese porphyrin complex obtained from NaOCl oxidation , 1983 .

[11]  N. Murugesan,et al.  Oxygen transfer from bleomycin-metal complexes. , 1982, The Journal of biological chemistry.

[12]  S. Hecht,et al.  Iron(II)-bleomycin. Biochemical and spectral properties in the presence of radical scavengers. , 1982, Biochemical and biophysical research communications.

[13]  S. Horwitz,et al.  Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA. , 1981, The Journal of biological chemistry.

[14]  C. Iden,et al.  Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage. , 1981, The Journal of biological chemistry.

[15]  R. Haushalter,et al.  High-valent iron-porphyrin complexes related to peroxidase and cytochrome P-450 , 1981 .

[16]  Y. Sugiura Bleomycin-iron complexes. Electron spin resonance study, ligand effect, and implication for action mechanism , 1980 .

[17]  M. J. Coon,et al.  Oxygen activation by cytochrome P-450. , 1980, Annual review of biochemistry.

[18]  V. Ullrich Cytochrome P450 and biological hydroxylation reactions. , 1979, Topics in current chemistry.

[19]  E. Sausville,et al.  Properties and products of the degradation of DNA by bleomycin and iron(II). , 1978, Biochemistry.

[20]  E. Sausville,et al.  Effect of chelating agents and metal ions on the degradation of DNA by bleomycin. , 1978, Biochemistry.

[21]  T. Beerman,et al.  Characterization of DNA strand breakage in vitro by the antitumor protein neocarzinostatin. , 1977, Biochemistry.